Patents by Inventor Eliot R. Spindel

Eliot R. Spindel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • M3 MUSCARINIC RECEPTOR ANTAGONISTS FOR TREATMENT OF M3 MUSCARINIC RECEPTOR-EXPRESSING TUMORS
    Publication number: 20090062326
    Abstract: The present disclosure provides methods of treating a tumor using M3 muscarininc receptor antagonists, such as darifenacin. In some examples, the tumor expresses M3 muscarinic receptors, such as tumors associated with smoking. Also provided are compositions that can be used to practice such methods.
    Type: Application
    Filed: March 16, 2007
    Publication date: March 5, 2009
    Inventors: Eliot R. Spindel, Harmanjatinder Sekhon, Pingfang Song
  • NUCLEIC ACIDS ENCODING RECEPTORS FOR BOMBESIN-LIKE PEPTIDES
    Publication number: 20010014457
    Abstract: Pure nucleic acids encoding novel receptors for bombesin-like peptides, the novel receptors themselves, and their antibodies. Also disclosed is a method of screening for a compound capable of interacting with any of these novel receptors.
    Type: Application
    Filed: September 24, 1998
    Publication date: August 16, 2001
    Inventors: ELIOT R. SPINDEL, SRINIVASA NAGALLA, BRENDA BARRY
  • Screening assays using nucleic acids encoding receptors for bombesin-like peptides
    Patent number: 5814463
    Abstract: Pure nucleic acids encoding novel receptors for bombesin-like peptides, the novel receptors themselves, and their antibodies. Also disclosed is a method of screening for a compound capable of interacting with any of these novel receptors.
    Type: Grant
    Filed: August 12, 1997
    Date of Patent: September 29, 1998
    Assignee: The Medical Research Foundation of Oregon
    Inventors: Eliot R. Spindel, Srinivasa Nagalla, Brenda Barry
  • Nucleic acids encoding receptors for bombesin-like peptides
    Patent number: 5656749
    Abstract: Pure nucleic acids encoding novel receptors for bombesin-like peptides, the novel receptors themselves, and their antibodies. Also disclosed is a method of screening for a compound capable of interacting with any of these novel receptors.
    Type: Grant
    Filed: July 22, 1994
    Date of Patent: August 12, 1997
    Assignee: Oregon Regional Primate Research Center
    Inventors: Eliot R. Spindel, Srinivasa Nagalla, Brenda Barry
  • Method of controlling fertilization using bombesin or its agonist
    Patent number: 5439884
    Abstract: A method of promoting or blocking fertilization, which method includes the step of contacting sperm either at the time of sperm capacitation or at the time of egg fertilization with an effective amount of bombesin or its analog capable of stimulating or inhibiting the acrosome reaction.
    Type: Grant
    Filed: July 27, 1992
    Date of Patent: August 8, 1995
    Assignee: Oregon Regional Primate Research Center
    Inventors: Eliot R. Spindel, Srinivasa R. Nagalla, Srinivasan Vijayaraghavan, Anthony Archibong
  • DNA sequence which encodes a peptide capable of promoting acrosome reaction
    Patent number: 5436137
    Abstract: A pure DNA encoding a peptide which is capable of promoting acrosome reaction and the encoded peptide. Also disclosed are a vector and a cell containing such a DNA, a pharmaceutical composition which includes such a peptide, a method of promoting fertilization using such a peptide, and a method of preparing such a peptide by recombinant technology.
    Type: Grant
    Filed: March 23, 1993
    Date of Patent: July 25, 1995
    Assignee: Oregon Regional Primate Research Center
    Inventors: Eliot R. Spindel, Srinivasan Vijayaraghavan, Srinivasa R. Nagalla, Kang Li
  • Bombesin-related peptides
    Patent number: 5410018
    Abstract: A pure DNA encoding a peptide which encodes a novel bombesin-related peptide, i.e., H-pGlu-Gln-Ser-Leu-Gly-Asn-Gin-Trp-Ala-Arg-Gly-His-Phe-Met-NH.sub.2 or Gly-Asn-Gln-Trp-Ala-Arg-Gly-His-Phe-Met-NH.sub.2. Also disclosed are a vector and a cell containing such a DNA, a pharmaceutical composition which includes such a peptide, and a method of preparing such a peptide by recombinant technology.
    Type: Grant
    Filed: February 25, 1994
    Date of Patent: April 25, 1995
    Assignee: Oregon Regional Primate Research Center
    Inventors: Eliot R. Spindel, Srinivasa Nagalla, Brenda Barry