Patents by Inventor Elisa Barile

Elisa Barile has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of Furin and other pro-protein convertases
    Patent number: 9266828
    Abstract: Disclosed herein are Furin/PC inhibitors for inhibiting Furin and other Propprotein Convertases. Method of making the Furin/PC inhibitors, chemical and biological characterization of the Furin/PC inhibitors, and the use of the Furin/PC inhibitors to treat infectious diseases, cancers, and inflammatory/autoimmune disorders, are also disclosed.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: February 23, 2016
    Assignee: SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
    Inventors: Alex Strongin, Maurizio Pellecchia, Elisa Barile
  • INHIBITORS OF FURIN AND OTHER PRO-PROTEIN CONVERTASES
    Publication number: 20150073054
    Abstract: Disclosed herein are Furin/PC inhibitors for inhibiting Furin and other Propprotein Convertases. Method of making the Furin/PC inhibitors, chemical and biological characterization of the Furin/PC inhibitors, and the use of the Furin/PC inhibitors to treat infectious diseases, cancers, and inflammatory/autoimmune disorders, are also disclosed.
    Type: Application
    Filed: March 14, 2013
    Publication date: March 12, 2015
    Inventors: Alex Strongin, Maurizio Pellecchia, Elisa Barile
  • INHIBITORS OF FURIN AND OTHER PRO-PROTEIN CONVERTASES
    Publication number: 20150051138
    Abstract: Disclosed herein are Furin/PC inhibitors for inhibiting Furin and other Propprotein Convertases. Method of making the Furin/PC inhibitors, chemical and biological characterization of the Furin/PC inhibitors, and the use of the Furin/PC inhibitors to treat infectious diseases, cancers, and inflammatory/autoimmune disorders, are also disclosed.
    Type: Application
    Filed: March 14, 2013
    Publication date: February 19, 2015
    Applicant: Sanford-Burnham Medical Research Institute
    Inventors: Alex Strongin, Maurizio Pellecchia, Elisa Barile
  • Pyrazole Derivatives as Kinase Inhibitors
    Publication number: 20110212961
    Abstract: The present invention provides compounds having the general structure I, or a pharmaceutically acceptable salt thereof: wherein X is a six-member ring selected from phenyl, pyridine, or pyrimidine; Y is H, an alkenyl, a substituted alkenyl, or alkynyl, and R is H or alkyl. Pharmaceutical compositions for treating various disorders such as cancers, the compositions including compound I are also provided.
    Type: Application
    Filed: May 9, 2011
    Publication date: September 1, 2011
    Inventors: Maurizio Pellecchia, Surya De, Elisa Barile
  • Pyrazole derivatives as kinase inhibitors
    Patent number: 7951832
    Abstract: The present invention provides compounds having the general structure I, or a pharmaceutically acceptable salt thereof: wherein X is a six-member ring selected from phenyl, pyridine, or pyrimidine; Y is H, an alkenyl, a substituted alkenyl, or alkynyl, and R is H or alkyl. Pharmaceutical compositions for treating various disorders such as cancers, the compositions including compound I are also provided.
    Type: Grant
    Filed: October 30, 2008
    Date of Patent: May 31, 2011
    Assignee: Burnham Institute for Medical Research
    Inventors: Maurizio Pellecchia, Surya De, Elisa Barile