Patents by Inventor Elisabet Kaisheva

Elisabet Kaisheva has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stable liquid and lyophilized formulation of proteins
    Publication number: 20060008415
    Abstract: The present invention is directed to stable protein derivatives, e.g., antibodies, antibody fragments or peptides, with at least one free thiol group coupled to N-acetyl-L-cysteine, N-ethyl-maleimide, or cysteine and the methods of making such derivatives. In addition, stable liquid pharmaceutical formulations comprising such proteins or their derivatives and stable lyophilized pharmaceutical formulations comprising such proteins are provided. The present invention is also directed to a method of making a stable Fab? fragment of an antibody and a method of controlling vascularization in injured or cancerous tissue comprising applying to the injured tissue one or more doses of the pharmaceutical formulations.
    Type: Application
    Filed: June 24, 2005
    Publication date: January 12, 2006
    Applicant: Protein Design Labs, Inc.
    Inventors: Elisabet Kaisheva, Supriya Gupta, Weichang Zhou, Robert Weinkam, Patrick Powers, Naichi Liu, Vanitha Ramakrishnan