Patents by Inventor Elisabeth Davioud-Charvet

Elisabeth Davioud-Charvet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PREPARATION OF 6-SUBSTITUTED MENADIONES
    Publication number: 20240327328
    Abstract: A process for the preparation of a compound having the following formula (I): wherein R is selected from the group consisting of: halogen, (C1-C6)alkoxy, (C1-C6)alkyl, halo(C1-C6)alkyl, and halo(C1-C6)alkoxy, said process including a step of intramolecular cyclisation, a step of bromination, a step of aromatization and a step of oxidation.
    Type: Application
    Filed: July 13, 2022
    Publication date: October 3, 2024
    Inventors: Elisabeth DAVIOUD-CHARVET, Nathan TROMETER, Maxime DONZEL, Matthieu ROIGNANT
  • HETEROAROMATIC ANALOGUES OF 3-BENZYLMENADIONE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION
    Publication number: 20240279184
    Abstract: A compound having the formula (I): wherein: R1 is selected from the group consisting of: H, F, (C1-C6)alkoxy, and halo(C1-C6)alkyl; and R2 is an optionally substituted heteroaryl group, as well as processes for the preparation of the compound, and intermediate compounds.
    Type: Application
    Filed: June 3, 2022
    Publication date: August 22, 2024
    Inventors: Elisabeth DAVIOUD-CHARVET, Maxime DONZEL, Matthieu ROIGNANT, Mourad ELHABIRI
  • PHOTOREDOX RADICAL BENZYLATION PROCESS
    Publication number: 20240174589
    Abstract: The present invention relates to a method for the preparation of a compound having the formula (I): wherein: R1, R2, R3, and R4 are in particular H or halogen, R5 is in particular (C1-C6)alkyl, R6 is a group of formula —CH?CH2 or a group having the below formula (II): said method comprising a reacting step carried out under light irradiation in the presence of an iron catalyst, a heteroatomic base, and a HAT agent.
    Type: Application
    Filed: March 4, 2022
    Publication date: May 30, 2024
    Inventors: Elisabeth DAVIOUD-CHARVET, Maxime DONZEL, Mourad ELHABIRI
  • Total synthesis of redox-active 1.4-naphthoquinones and their metabolites and their therapeutic use as antimalarial and schistomicidal agents
    Patent number: 9409879
    Abstract: Naphthoquinones, azanaphthoquinones and benxanthones, their process of synthesis and methods of their use as antimalarial or antischistosomal agents.
    Type: Grant
    Filed: March 29, 2012
    Date of Patent: August 9, 2016
    Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Elisabeth Davioud-Charvet, Don Antoine Lanfranchi, Laure Johann, David Lee Williams, Elena Cesar Rodo
  • Compounds useful against kinetoplastideae parasites
    Patent number: 9174960
    Abstract: Dibenzylidene and heterobenzylideneacetone derivatives, related 4-piperidones, related 4-thiopyranones and the corresponding sulfinyl- and sulfonyl-analogues for their use for prophylaxis or treatment of trypanosomiasis and leishmaniasis.
    Type: Grant
    Filed: September 20, 2010
    Date of Patent: November 3, 2015
    Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Elisabeth Davioud-Charvet, Ingrid Nicole Wenzel, Thomas J. J. Müller, Gilles Hanquet, Don Antoine Lanfranchi, Frédéric Leroux, Thibault Gendron
  • 1,4-naphthoquinones derivatives and therapeutic use thereof
    Patent number: 9090549
    Abstract: 1,4 naphthoquinones derivatives, of formula (I) wherein A is selected from the following rings: their preparation and their application as antimalarial agents
    Type: Grant
    Filed: March 25, 2009
    Date of Patent: July 28, 2015
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), REPRECHT-KARLS-UNIVERSITAT HEIDELBERG
    Inventors: Elisabeth Davioud-Charvet, Tobias Muller, Holger Bauer, R. Heiner Schirmer
  • FLAVONE DERIVATIVES AND THEIR USE
    Publication number: 20150056166
    Abstract: The present invention relates to flavone derivatives and to compositions containing one or more of these flavone derivatives. The present invention further relates to flavone derivatives or compositions for use in the treatment and/or prevention of a viral infection, and to a method of preventing or treating these infections.
    Type: Application
    Filed: March 22, 2013
    Publication date: February 26, 2015
    Inventors: Thomas Pietschmann, Sibylle Haid, Juliane Gentzsch, Christina Grethe, Elisabeth Davioud-Charvet, Don Antoine Lanfranchi, Mourad Elhabiri, Xavier Benlloch-Martin
  • TOTAL SYNTHESIS OF REDOX-ACTIVE 1.4-NAPHTHOQUINONES AND THEIR METABOLITES AND THEIR THERAPEUTIC USE AS ANTIMALARIAL AND SCHISTOMICIDAL AGENTS
    Publication number: 20140121238
    Abstract: Naphthoquinones, azanaphthoquinones and benxanthones, their process of synthesis and methods of their use as antimalarial or antischistosomal agents.
    Type: Application
    Filed: March 29, 2012
    Publication date: May 1, 2014
    Applicant: Centre National De La Recherche Scientifique
    Inventors: Elisabeth Davioud-Charvet, Don Antoine Lanfranchi, Laure Johann, David Lee Williams, Elena Cesar Rodo
  • COMPOUNDS USEFUL AGAINST KINETOPLASTIDEAE PARASITES
    Publication number: 20120214996
    Abstract: Dibenzylidene and heterobenzylideneacetone derivatives, related 4-piperidones, related 4-thiopyranones and the corresponding sulfinyl- and sulfonyl-analogues for their use for prophylaxis or treatment of trypanosomiasis and leishmaniasis.
    Type: Application
    Filed: September 20, 2010
    Publication date: August 23, 2012
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Elisabeth Davioud-Charvet, Ingrid Nicole Wenzel, Thomas J.J. Muller, Gilles Hanquet, Don Antoine Lanfranchi, Frederic Leroux, Thibault Gendron
  • Phosphole derivatives complexed with metals, and pharmaceutical uses thereof
    Patent number: 7923434
    Abstract: The invention concerns pharmaceutical compositions comprising as active compound at least one compound of general formula (A), wherein: M represents a metal atom, and their uses in particular for preventing or treating pathologies associated with an excess activity of glutathion reductase and/or thioredoxin reductase.
    Type: Grant
    Filed: July 29, 2005
    Date of Patent: April 12, 2011
    Assignee: Centre National de la Recherche Scientifique
    Inventors: Elisabeth Davioud-Charvet, Katja Becker-Brandenburg, Valérie Deborde, Régis Reau, R. Heiner Schirmer, Christel Herold-Mende
  • 1,4-NAPHTHOQUINONES DERIVATIVES AND THERAPEUTIC USE THEREOF
    Publication number: 20110059972
    Abstract: 1,4 naphthoquinones derivatives, of formula (I) wherein A is selected from the following rings: their preparation and their application as antimalarial agents
    Type: Application
    Filed: March 25, 2009
    Publication date: March 10, 2011
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Elisabeth Davioud-Charvet, Tobias Muller, Holger Bauer, R. Heiner Schirmer
  • Phosphole Derivatives Complexed with Metals, and Pharmaceutical Uses Thereof
    Publication number: 20080045465
    Abstract: The invention concerns pharmaceutical compositions comprising as active compound at least one compound of general formula (A), wherein: M represents a metal atom, and their uses in particular for preventing or treating pathologies associated with an excess activity of glutathion reductase and/or thioredoxin reductase.
    Type: Application
    Filed: July 29, 2005
    Publication date: February 21, 2008
    Inventors: Elisabeth Davioud-Charvet, Katja Becker-Brandenburg, Valerie Deborde, Regis Reau, R. Heiner Schirmer, Christel Herold-Mende
  • Substituted dithiobisnitrobenzenes and their applications
    Publication number: 20030175848
    Abstract: The invention concerns substituted dithio-bis-nitrobenzenes (dithio-bis-nitrobenzylamines, dithio-bis-nitrobenzamides or dithio-bis-nitrophenacyls) and their uses as alternative substrates for NAD(P)H-dependent disulphide-reductase enzymes, such as trypanothion reductase and thioredoxine reductase and as a means for screening inhibitors of said enzymes. The invention also concerns an enzymatic test using said substrates and assay kits containing them. Said dithio-bis-nitrobenzenes correspond to general formula (I).
    Type: Application
    Filed: January 22, 2003
    Publication date: September 18, 2003
    Applicant: Institut Pasteur De Lille
    Inventors: Elisabeth Davioud-Charvet, Christian Sergheraert, Katja Becker-Brandenburg, Heiner Schirmer