Patents by Inventor Elisabeth J. S. Meulenhoff

Elisabeth J. S. Meulenhoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transgenic fungal resistant plants expressing chitinase and glucanase, process for obtaining, and recombinant polynucleotides for uses therein
    Patent number: 6087560
    Abstract: Plants are provided with improved resistance against pathogenic fungi. They are genetically transformed with one or more polynucleotides which essentially comprise one or more genes encoding plant chitinases and .beta.-1,3-glucanases. Preferred are the intracellular forms of the said hydrolytic enzymes, especially preferred are those forms which are targeted to the apoplastic space of the plant by virtue of the modification of the genes encoding the said enzymes. Particularly preferred are plants exhibiting a relative overexpression of at least one gene encoding a chitinase and one gene encoding a .beta.-1,3-glucanase.
    Type: Grant
    Filed: February 18, 1997
    Date of Patent: July 11, 2000
    Assignees: Rijksuniversiteit te Leiden, Mogen International, N.V.
    Inventors: Bernardus J. C. Cornelissen, Leo Sjoerd Melchers, Elisabeth J. S. Meulenhoff, Jeroen S. C. van Roekel, Marianne Beatrix Sela-Buurlage, Alexandra Aleida Vloemans, Charles Peter Woloshuk, John Ferdinand Bol, Hubertus J. M. Linthorst
  • Fungal resistant plants, process for obtaining fungal resistant plants and recombinant polynucleotides for use therein
    Patent number: 5670706
    Abstract: Plants are provided with improved resistance against pathogenic fungi. They are genetically transformed with one or more polynucleotides which essentially comprise one or more genes encoding plant chitinases and .beta.-1,3-glucanases. Preferred are the intracellular forms of the said hydrolytic enzymes, especially preferred are those forms which are targeted to the apoplastic space of the plant by virtue of the modification of the genes encoding the said enzymes. Particularly preferred are plants exhibiting a relative overexpression of at least one gene encoding a chitinase and one gene encoding a .beta.-1,3-glucanase.
    Type: Grant
    Filed: April 19, 1993
    Date of Patent: September 23, 1997
    Assignees: MOGEN International, n.v., Rijksuniversiteit te Leiden
    Inventors: Bernardus J. C. Cornelissen, Leo Sjoerd Melchers, Elisabeth J. S. Meulenhoff, Jeroen S. C. van Roekel, Marianne Beatrix Sela-Buurlage, Alexandra Aleida Vloemans, Charles Peter Woloshuk, John Ferdinand Bol, Hubertus J. M. Linthorst
  • Antifungal preparations, and process for making such preparations
    Patent number: 5389609
    Abstract: New methods are provided for the identification and purification of proteins from plants with an inhibitory effect on pathogens and/or pests, such as insects, nematodes, fungi, and bacteria, using a combination of non-denaturing protein fractionation techniques on leaf-extracts of plants which were treated to develop induced resistance and an antipathogenic assay. Also provided are antifungal proteins obtained by the method, recombinant nucleotide sequences encoding the proteins, as well as plants with reduced susceptibility to fungi due to production and desired targeting of the proteins in the plant.
    Type: Grant
    Filed: April 6, 1992
    Date of Patent: February 14, 1995
    Assignee: Mogen International N.V.
    Inventors: Charles P. Woloshuk, Leo S. Melchers, Bernardus J. C. Cornelissen, Elisabeth J. S. Meulenhoff, Marianne B. Sela-Buurlage, Petrus J. M. Van Den Elzen