Patents by Inventor Elisabeth Tournier-Lasserve

Elisabeth Tournier-Lasserve has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of the gene in the field of angiogenesis
    Patent number: 7364844
    Abstract: The invention concerns a method for diagnosing cavernous angiomas for detecting mutations in the Krit1 gene. More particularly, said detection is performed by using nucleotide sequences. The invention further concerns the use of the Krit1 gene for therapeutic purposes in the field of angiogenesis.
    Type: Grant
    Filed: July 3, 2000
    Date of Patent: April 29, 2008
    Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Elisabeth Tournier-Lasserve, Sophie Laberge-Le-Couteulx, Pierre Labauge
  • Gene involved in CADASIL, method of diagnosis and therapeutic application
    Patent number: 7138234
    Abstract: The invention concerns the Notch3 gene and the corresponding protein, which are involved in CADASIL. The invention concerns, in particular, methods for demonstrating mutations in this gene, which are linked to the risk of developing CADASIL and related diseases.
    Type: Grant
    Filed: February 3, 2003
    Date of Patent: November 21, 2006
    Assignees: Institut National de la Sante et de la Recherche Medicale (INSERM), Assistance Publique-Hopitaux de Paris
    Inventors: Elisabeth Tournier-Lasserve, Anne Joutel, Marie-Germaine Bousser, Jean-François Bach
  • Gene involved in CADASIL, method of diagnosis and therapeutic application
    Patent number: 6995257
    Abstract: The invention concerns the Notch3 gene and the corresponding protein, which are involved in CADASIL. The invention concerns, in particular, methods for demonstrating mutations in this gene, which are linked to the risk of developing CADASIL. The invention also concerns models and products for treating CADASIL and related diseases.
    Type: Grant
    Filed: July 7, 2000
    Date of Patent: February 7, 2006
    Assignees: Institut National de la Santa et de la Recherche (INSERM), Assistance Publique - Hopitaux de Paris
    Inventors: Elisabeth Tournier-Lasserve, Anne Joutel, Marie-Germaine Bousser, Jean-François Bach
  • Gene involved in CADASIL, method of diagnosis and therapeutic application
    Publication number: 20030186290
    Abstract: The invention concerns the Notch3 gene and the corresponding protein, which are involved in CADASIL. The invention concerns, in particular, methods for demonstrating mutations in this gene, which are linked to the risk of developing CADASIL. The invention also concerns models and products for treating CADASIL and related diseases.
    Type: Application
    Filed: February 3, 2003
    Publication date: October 2, 2003
    Applicant: Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Elisabeth Tournier-Lasserve, Anne Joutel, Marie-Germaine Bousser, Jean-Francois Bach
  • Gene involved in cadasil, method of diagnosis and therapeutic application
    Patent number: 6537775
    Abstract: The invention concerns the Notch3 gene and the corresponding protein, which are involved in CADASIL. The invention concerns, in particular, methods for demonstrating mutations in this gene, which are linked to the risk of developing CADASIL. The invention also concerns models and products for treating CADASIL and related diseases.
    Type: Grant
    Filed: May 17, 1999
    Date of Patent: March 25, 2003
    Assignees: Institut National de la Sante et de la Recherche (INSERM), Assistance Publique - Hopitaux de Paris
    Inventors: Elisabeth Tournier-Lasserve, Anne Joutel, Marie-Germaine Bousser, Jean-François Bach
  • Method for the diagnosis of CADASIL
    Patent number: 5616462
    Abstract: Genotypic diagnosis of CADASIL for symptomatic or at risk individuals or fetuses belonging to a family suspected of being affected by CADASIL is carried out by detecting DNA polymorphisms genetically linked to the mutated gene responsible for CADASIL, these DNA polymorphisms being located in the genetic interval of the chromosome 19 flanked by the microsatellites D198221 and D19S215 and including these microsatellites.
    Type: Grant
    Filed: February 28, 1994
    Date of Patent: April 1, 1997
    Assignee: L'Assistance Publique--Hospitaux de Paris
    Inventors: Anne M. G. Joutel, Marie-Germaine M. Bousser, Elisabeth A. Tournier-Lasserve