Patents by Inventor Elise Brownell

Elise Brownell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cancer Treatment Using Camptothecin Derivatives
    Publication number: 20220395497
    Abstract: A method of treating cancer in a patient by administering to a patient a composition comprising a therapeutically effective amount of AR-67, wherein the method is at least as effective as the administration of a dose of other camptothecins delivered alone or as a combination therapy, and wherein the method reduces the incidence of one or more adverse events.
    Type: Application
    Filed: November 19, 2020
    Publication date: December 15, 2022
    Applicant: Vivacitas Oncology, Inc.
    Inventor: Elise BROWNELL
  • A BIOMARKER FOR ALZHEIMER'S DISEASE USING BLOOD SAMPLES FROM CLINICALLY DIAGNOSED ALZHEIMER'S DISEASE SUBJECTS
    Publication number: 20220260595
    Abstract: The current invention discloses a method for diagnosing Alzheimer disease by using biomarkers, and multivariate analysis which gives a more reliable, minimally- or non-invasive method of detection. The invention discloses simultaneous detection of CD69 protein in mitogenic lymphocytes, tau and phosphorylated tau proteins, and amyloid-? peptides in cerebrospinal fluid, which can replace or supplement conventional methods of detection of Alzheimer's disease such as cognitive testing and amyloid-positron emission tomography.
    Type: Application
    Filed: July 10, 2020
    Publication date: August 18, 2022
    Inventors: Elise BROWNELL, Paula TRZEPACZ, Gerald COMMISSIONG, Herman WEISS, Thomas ARENDT
  • Cytotoxic T-lymphocyte antigen as cysteine protease inhibitor
    Patent number: 5973110
    Abstract: Disclosed are molecules which inhibit the proteolytic activity of cysteine proteases such as Cathepsin H, Cathepsin L and papain, and methods for using molecules which have the biological properties of cytotoxic T-lymphocyte antigen for inhibiting cysteine proteases and inhibiting proteoglycan degradation.
    Type: Grant
    Filed: May 18, 1995
    Date of Patent: October 26, 1999
    Assignee: Bayer Corporation
    Inventors: Daniel Muller, Katherine Delaria, Linda Wallace, Elise Brownell
  • Cytotoxic T-lymphocyte antigen as cysteine protease inhibitor
    Patent number: 5962633
    Abstract: Disclosed are molecules which inhibit the proteolytic activity of cysteine proteases such as Cathespin H, Cathespin L and papain, and methods for using molecules which have the biological properties of cytotoxic T-lymphoyte antigen for inhibiting cysteins proteases and inhibiting proteolglycan degradation.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: October 5, 1999
    Assignee: Bayer Corporation
    Inventors: Daniel Muller, Katherine Delaria, Linda Wallace, Elise Brownell
  • Method for treating asthma using SCF antibody
    Patent number: 5911988
    Abstract: This invention provides pharmaceutical compositions comprising anti-SCF antibodies for the reduction of eosinophila in the lungs of mammals. This invention also provides for methods of treating asthma and generating a murine model for asthma.
    Type: Grant
    Filed: August 18, 1997
    Date of Patent: June 15, 1999
    Assignees: Bayer Corporation, Univ. of Michigan
    Inventors: Elise Brownell, Nicholas Lukacs, Steven L. Kunkel, Robert M. Strieter
  • Secretory leukocyte protease inhibitor as an inhibitor of tryptase
    Patent number: 5633227
    Abstract: This invention concerns methods of treating mast-cell mediated conditions in mammals, the methods comprising administering to the mammals pharmacologically active fragments or muteins of SLPI; methods of treating asthma or allergic rhinitis in mammals, the methods comprising administering to the mammals SLPI or pharmacologically active fragments or muteins thereof; methods for inhibiting tryptase; methods for identifying inhibitors of tryptase; and certain fragments and muteins of SLPI.
    Type: Grant
    Filed: September 12, 1994
    Date of Patent: May 27, 1997
    Assignee: Miles, Inc.
    Inventors: Daniel K. Muller, Elise Brownell, Katherine A. Delaria