Patents by Inventor Elishalom Yechiel

Elishalom Yechiel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for reversing age-related changes in heart muscle cells
    Patent number: 6348213
    Abstract: A method of-treating a relatively aged animal to reverse age-related changes in the lipid composition of organ and tissue cells, such as heart muscle cells, and the ability of the animal to withstand respiratory stress. A suspension of small unilamellar vesicles composed predominantly of egg phosphatidyl choline is administered parenterally to the animal, preferably over a period of several days and at a dose level of between about 0.1 and 1 grams lipid per kg body weight per day. Changes in the heart muscle cells are reflected in decreased levels of serum creatine phosphokinase. Liposome administration is continued until the serum creatine phosphokinase level drops at least about 50%. Also disclosed are liposome treatment methods for increasing longevity and male fertility.
    Type: Grant
    Filed: May 3, 1994
    Date of Patent: February 19, 2002
    Assignees: Yissum Research and Development Co. of The Hebrew University of Jerusalem, Hadassah Medical Organization
    Inventors: Yechezkel Barenholz, Elishalom Yechiel
  • Lipid replacement therapy
    Patent number: 4812314
    Abstract: A method of treating a relatively aged animal to reverse age-related changes in the lipid composition of organ and tissue cells, such as heart muscle cells, and the ability of the animal to withstand respiratory stress. A suspension of small unilamellar vesicles composed predominantly of egg phosphatidyl choline is administered parenterally to the animal, preferably over a period of several days and at a dose level of between about 0.1 and 1 grams lipid per kg body weight per day. Changes in the heart muscle cells are reflected in decreased levels of serum creatine phosphokinase. Liposome administration is continued until the serum creatine phosphokinase level drops at least about 50%. Also disclosed are liposome treatment methods for increasing longevity and male fertility.
    Type: Grant
    Filed: February 24, 1986
    Date of Patent: March 14, 1989
    Assignee: Yissum Research & Dev. Co. of the Hebrew Univ. of Jerusalem and Hadassah Medical Organization
    Inventors: Yechezkel Barenholz, Elishalom Yechiel