Abstract: The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), cognitive impairment (e.g.

Abstract: The present disclosure generally relates to methods and systems for generating a void profile for user void events. The method includes receiving by a processing element a plurality of outputs from a fluid level sensor corresponding to a plurality of levels of fluid flowing through a voiding device during a flow event; determining by the processing element a beginning and an end time of the fluid flow into the voiding device during the flow event; analyzing the plurality of outputs of the fluid level sensor over a time interval defined by the beginning and end time of the fluid flow to determine at least one of a fluid flow rate data and an accumulated volume data for the fluid flowing through the voiding device; and storing the fluid flow rate data and the accumulated flow volume data in a memory.

Abstract: Uroflowmeters and methods for processing data generated therefrom are disclosed. In one aspect, the uroflowmeter is a handheld device. The uroflowmeter includes a handle, a flow chamber coupled to the handle, and a sensor associated with the flow chamber that detects a parameter of urine received in the flow chamber. The uroflowmeter may include both reusable and disposable components. As a uroflowmeter it can identify and record data corresponding to the rate of flow over the measured duration of a void of urine, but may also timestamp the voiding act and communicate the data to an external data collection center for additional analysis and incorporation into a comprehensive voiding report or voiding diary.

Abstract: Disclosed are various embodiments for customizing an item search and browsing experience based on a delivery speed preference. A request is received from a client device for a detail page regarding a particular item offered for order. A first delivery speed option associated with the client device is identified. It is determined that the particular item cannot be delivered to a particular address associated with the client device via the first delivery speed option. A user interface is generated that indicates a second delivery speed option via which the particular item is available for delivery to the particular address. Data encoding the user interface is sent to the client device for rendering on a display.

Abstract: Disclosed are various embodiments for customizing an item search and browsing experience based on a delivery speed preference. Multiple delivery speed options are generated for a client device, and a listing of the delivery speed options are sent to the client device. A user selection of a particular delivery speed option is then received from the client device. An item search criterion is received from the client device. A listing of items selected from an electronic item database is generated based at least in part on the item search criterion and item availability via the particular delivery speed option. Data encoding the listing of items is sent to the client device for rendering on a display.

Abstract: Methods and compositions for stimulating of the production of hydrocarbons (e.g., formation crude oil and/or formation gas) from subterranean formations, and methods of selecting a composition for treating an oil or gas well. In some embodiments, the compositions are emulsions or microemulsions, which may include water, a terpene, and a surfactant.

Abstract: A dual component insert for use with a spray actuator for dispensing a pressurized product. The dual component insert comprises a support insert and an insert disk. The support insert includes a base wall which has a support discharge orifice formed therein and a cylindrical wall is formed integral with and extends from the base wall so as to define an insert cavity. The insert disk has a disk discharge orifice, a diameter of the disk discharge orifice is smaller than a diameter of the support discharge orifice, and the insert disk is received and captively retained within the insert cavity so that the disk discharge orifice is axially aligned with the support discharge orifice. The insert disk is manufactured from a relatively thin durable material which facilitates fabrication of a consistent, accurate, uniform and well defined small diameter discharge orifice which results in dispensing a fine mist spray.

Abstract: Methods and compositions comprising an emulsion or a microemulsion for use in various aspects of the life cycle of an oil and/or gas well are provided. In some embodiments, the emulsion or the microemulsion comprises water, a solvent, and a surfactant, and optionally, one or more additives.

Abstract: An improved mounting cup and valve assembly combination for an aerosol container. The combination comprises a mounting cup which has a pedestal portion and a perimeter curl, a valve stem which has a product outlet and at least one radial orifice formed therein which communicates with the product outlet, an open ended valve body defining an interior chamber, the valve body has a dip tube coupling adjacent a partially closed base thereof, and the dip tube coupling facilitates conveying product to be dispensed into the interior chamber of the valve body, and a gasket is sandwiched between the mounting cup and the valve body. The base of the valve body forms a first seat while a surface of the valve stem, facing toward the dip tube coupling, forms a second seat. A rubber compressible member is captively retained between the first and the second seats.

Abstract: Methods and compositions for stimulating of the production of hydrocarbons (e.g., formation crude oil and/or formation gas) from subterranean formations, and methods of selecting a composition for treating an oil or gas well. In some embodiments, the compositions are emulsions or microemulsions, which may include water, a terpene, and a surfactant.

Abstract: A dispensing valve comprising a metering valve for a pressurized aerosol application. The dispensing valve comprises a mounting cup, a gasket, a valve body and a valve housing defining a cavity. The valve housing is captively retained by the mounting cup and a spring biasing the valve body against the gasket into a normally closed position. A lower portion of the valve housing communicating with the product to be dispensed. A valve stem is coupled to the valve body and an actuator is supported by the valve stem. The metering valve is delimited by a metering valve seat and a stop. A metering member is movable, within the metering chamber, to dispense a predetermined quantity of product. The metering valve seat comprising at least one micro vent which facilitates supplying air to the metering valve seat to break a seal formed by surface tension of the product to be dispensed.

Abstract: Methods and compositions for stimulating of the production of hydrocarbons (e.g., formation crude oil and/or formation gas) from subterranean formations are provided. In some embodiments, the compositions are emulsions or microemulsions, which may include water, a terpene, and a surfactant. In some embodiments, methods of selecting a composition for treating an oil or gas well are provided.

Abstract: Methods and compositions for stimulating of the production of hydrocarbons (e.g., formation crude oil and/or formation gas) from subterranean formations, and methods of selecting a composition for treating an oil or gas well. In some embodiments, the compositions are emulsions or microemulsions, which may include water, a terpene, and a surfactant.

Abstract: An improved mounting cup and valve assembly combination for an aerosol container. The combination comprises a mounting cup which has a pedestal portion and a perimeter curl, a valve stem which has a product outlet and at least one radial orifice formed therein which communicates with the product outlet, an open ended valve body defining an interior chamber, the valve body has a dip tube coupling adjacent a partially closed base thereof, and the dip tube coupling facilitates conveying product to be dispensed into the interior chamber of the valve body, and a gasket is sandwiched between the mounting cup and the valve body. The base of the valve body forms a first seat while a surface of the valve stem, facing toward the dip tube coupling, forms a second seat. A rubber compressible member is captively retained between the first and the second seats.

Abstract: Methods and compositions for stimulating of the production of hydrocarbons (e.g., formation crude oil and/or formation gas) from subterranean formations are provided. In some embodiments, the compositions are emulsions or microemulsions, which may include water, a terpene, and a surfactant. In some embodiments, methods of selecting a composition for treating an oil or gas well are provided.

Abstract: A dual component insert for use with a spray actuator for dispensing a pressurized product. The dual component insert comprises a support insert and an insert disk. The support insert includes a base wall which has a support discharge orifice formed therein and a cylindrical wall is formed integral with and extends from the base wall so as to define an insert cavity. The insert disk has a disk discharge orifice, a diameter of the disk discharge orifice is smaller than a diameter of the support discharge orifice, and the insert disk is received and captively retained within the insert cavity so that the disk discharge orifice is axially aligned with the support discharge orifice. The insert disk is manufactured from a relatively thin durable material which facilitates fabrication of a consistent, accurate, uniform and well defined small diameter discharge orifice which results in dispensing a fine mist spray.

Abstract: Methods and compositions for stimulating of the production of hydrocarbons (e.g., formation crude oil and/or formation gas) from subterranean formations, and methods of selecting a composition for treating an oil or gas well. In some embodiments, the compositions are emulsions or microemulsions, which may include water, a terpene, and a surfactant.

Abstract: Methods and compositions comprising an emulsion or a microemulsion for use in various aspects of the life cycle of an oil and/or gas well are provided. In some embodiments, the emulsion or the microemulsion comprises water, a solvent, and a surfactant, and optionally, one or more additives.

Abstract: Methods and compositions for stimulating of the production of hydrocarbons (e.g., formation crude oil and/or formation gas) from subterranean formations, and methods of selecting a composition for treating an oil or gas well. In some embodiments, the compositions are emulsions or microemulsions, which may include water, a terpene, and a surfactant.

Abstract: Disclosed are various embodiments for customizing an item search and browsing experience based on a delivery speed preference. Multiple delivery speed options are generated for a client device, and a listing of the delivery speed options are sent to the client device. A user selection of a particular delivery speed option is then received from the client device. An item search criterion is received from the client device. A listing of items selected from an electronic item database is generated based at least in part on the item search criterion and item availability via the particular delivery speed option. Data encoding the listing of items is sent to the client device for rendering on a display.