Abstract: A series of imidazo[1,2-a]pyridine derivatives of formula (I), being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.

Abstract: A series of imidazo[1,2-a]pyridine derivatives of formula (I), being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.

Abstract: A series of imidazo[1,2-?]pyrazine derivatives, being potent modulators of human TNF? activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorder; and oncological disorders.

Abstract: A trigger pump sprayer in combination with a liquid dispensed from the sprayer. The trigger sprayer provides for efficacious particle size distributions of the liquids, when sprayed under non-ideal conditions. Non-ideal conditions include only partial strokes of the trigger, rather than full strokes and relatively slow trigger strokes. A bimodal distribution of particle sizes is obtained under two different operating conditions. The sprayer/liquid combination according to the present invention compresses the difference between the two modes, without requiring undue work by the operator. The advantageous particle size distribution difference is accomplished by using a precompression piston which reciprocates in response to trigger strokes, and selecting a liquid having appropriate properties to correspond to the trigger pump operating characteristics.

Abstract: A trigger pump sprayer in combination with a liquid dispensed from the sprayer. The sprayer is suitable for dispensing liquid from a reservoir, through a nozzle into particles. The trigger sprayer provides for efficacious particle size distributions of the liquids, when sprayed under non-ideal conditions. Non-ideal conditions include only partial strokes of the trigger, rather than full strokes and relatively slow trigger strokes. The trigger sprayer advantageously delivers a particle size distribution suitable for liquids having particular rheological properties. The advantageous particle size distribution difference is accomplished by using a precompression piston which reciprocates in response to trigger strokes, and selecting a liquid having appropriate properties to correspond to the trigger pump operating characteristics.

Abstract: The present invention provides a natural wood, odor neutralizing, drying rack for sporting equipment, and other items to be dried. The wood which makes up the portion of the rack in contact with sporting equipment or other objects to be dried is not finished in any way, but is rather is left in its natural condition.

Abstract: A trigger pump sprayer in combination with a liquid dispensed from the sprayer. The sprayer is suitable for dispensing liquid from a reservoir, through a nozzle into particles. The trigger sprayer provides for efficacious particle size distributions of the liquids, when sprayed under non-ideal conditions. Non-ideal conditions include only partial strokes of the trigger, rather than full strokes and relatively slow trigger strokes. The trigger sprayer advantageously delivers a particle size distribution suitable for liquids having particular rheological properties. The advantageous particle size distribution difference is accomplished by using a precompression piston which reciprocates in response to trigger strokes, and selecting a liquid having appropriate properties to correspond to the trigger pump operating characteristics.

Abstract: A trigger pump sprayer in combination with a liquid dispensed from the sprayer. The trigger sprayer provides for efficacious particle size distributions of the liquids, when sprayed under non-ideal conditions. Non-ideal conditions include only partial strokes of the trigger, rather than full strokes and relatively slow trigger strokes. A bimodal distribution of particle sizes is obtained under two different operating conditions. The sprayer/liquid combination according to the present invention compresses the difference between the two modes, without requiring undue work by the operator. The advantageous particle size distribution difference is accomplished by using a precompression piston which reciprocates in response to trigger strokes, and selecting a liquid having appropriate properties to correspond to the trigger pump operating characteristics.

Abstract: A method is provided for analyzing operational risk associated with one or more organizations, comprising receiving operational loss data from a plurality of organizations at a third-party risk management entity that is a separate entity from the plurality of organizations. The operational loss data includes confidential information regarding one or more of the plurality of organizations. The data received from the plurality of organizations, including the confidential information, is pooled. The pooled data is used to generate an operational risk model for one of the plurality of organizations, and this operational risk model is transmitted to the organization. A system for modeling operational risk for a plurality of organizations is provided, comprising a first data store configured to collect data regarding operational losses from the plurality of organizations, whose data includes confidential information regarding one or more of the organizations.

Abstract: A system and method for generating and delivering an electronic form to a user. One embodiment of the disclosed system comprises a file management sub-system for receipt and management of at least one standard form in electronic format. The system also includes a user sub-system for selection of a desired form. In addition, the system includes a mapper sub-system for mapping each of the at least one standard forms into a form file identifying the graphical and/or textual elements of the standard form, at least one data field to placed on the form and an indication of where the at least one data field is to be placed based on the identified graphical and/or textual elements. Also, the system includes a delivery sub-system operably connected to the file management sub-system, the user sub-system and the mapping sub-system and capable delivering an electronic form comprising the desired form into which data retrieved from the user sub-system is inserted.

Abstract: Independently adjustable ladder extensions for use with folding, step, or extension ladders includes at least one pair of adjustable support legs slidably disposed within the channels of the side rails and having apertures that align with through holes on the side rails so that the support legs can be slidably adjusted within the channels and then locked in the desired position for stabilizing and leveling the ladder on an uneven surface. Locking pins insert into the through holes of the side rails and through the apertures of the support legs for locking the support legs in the position, and the locking pins include a flap member for holding the locking pins in position.

Abstract: A system and method for generating and delivering an electronic form to a user. One embodiment of the disclosed system comprises a file management sub-system for receipt and management of at least one standard form in electronic format. The system also includes a user sub-system for selection of a desired form. In addition, the system includes a mapper sub-system for mapping each of the at least one standard forms into a form file identifying the graphical and/or textual elements of the standard form, at least one data field to placed on the form and an indication of where the at least one data field is to be placed based on the identified graphical and/or textual elements. Also, the system includes a delivery sub-system operably connected to the file management sub-system, the user sub-system and the mapping sub-system and capable delivering an electronic form comprising the desired form into which data retrieved from the user sub-system is inserted.

Abstract: Independently adjustable ladder extensions for use with folding, step, or extension ladders includes at least one pair of ladder extensions with each ladder extension including an adjustable leg disposed within and encompassed by the lower end of the ladder side rail and having apertures that align with through holes of the side rail so that the leg can be slidably adjusted within the side rail and then locked in the desired position for stabilizing and leveling the ladder on an uneven surface. A locking pin inserts into the through holes of the side rail and through the apertures of the leg for locking the adjustable leg in the desired position, and the locking pin includes a flap member for holding the locking pin on the side rail. A traction foot is pivotally mounted to the bottom of each adjustable leg to facilitate the stabilization of the ladder on the uneven surface.