Patents by Inventor Elizabeth A. Jurica

Elizabeth A. Jurica has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrrolidine GPR40 modulators
    Patent number: 10301260
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, a tautomer, a pharmaceutically acceptable salt, a polymorph, or a solvate thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.
    Type: Grant
    Filed: May 6, 2015
    Date of Patent: May 28, 2019
    Assignee: Bristol-Myers Squibb Company
    Inventors: Xiang-Yang Ye, Bruce A. Ellsworth, Elizabeth A. Jurica
  • PYRROLIDINE GPR40 MODULATORS
    Publication number: 20180099949
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, a tautomer, a pharmaceutically acceptable salt, a polymorph, or a solvate thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.
    Type: Application
    Filed: December 13, 2017
    Publication date: April 12, 2018
    Inventors: Elizabeth A. Jurica, Zhenqiu Hong
  • Pyrrolidine GPR40 modulators
    Patent number: 9873679
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, a tautomer, a pharmaceutically acceptable salt, a polymorph, or a solvate thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.
    Type: Grant
    Filed: May 6, 2015
    Date of Patent: January 23, 2018
    Assignee: Bristol-Myers Squibb Company
    Inventors: Elizabeth A. Jurica, Zhenqiu Hong
  • Pyrrolidine GPR40 modulators
    Patent number: 9714231
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.
    Type: Grant
    Filed: November 15, 2013
    Date of Patent: July 25, 2017
    Assignee: Bristol-Myers Squibb Company
    Inventors: Bruce A. Ellsworth, Elizabeth A. Jurica, Jun Shi, William R. Ewing, Xiang-Yang Ye, Ximao Wu, Zhu Yeheng, Sun Chongqing
  • Dihydropyrazole GPR40 modulators
    Patent number: 9604964
    Abstract: The present invention provides compounds of Formula (I): (Formula (I), or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.
    Type: Grant
    Filed: November 15, 2013
    Date of Patent: March 28, 2017
    Assignee: Bristol-Myers Squibb Company
    Inventors: Bruce A. Ellsworth, Jun Shi, William R. Ewing, Elizabeth A. Jurica, Andres S. Hernandez, Ximao Wu, Zhengxiang Gu, Zhenqiu Hong, Stephen P. O'Connor
  • PYRROLIDINE GPR40 MODULATORS
    Publication number: 20170081282
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, a tautomer, a pharmaceutically acceptable salt, a polymorph, or a solvate thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.
    Type: Application
    Filed: May 6, 2015
    Publication date: March 23, 2017
    Inventors: Xiang-Yang Ye, Bruce A. Ellsworth, Elizabeth A. Jurica
  • DIHYDROPYRAZOLE GPR40 MODULATORS
    Publication number: 20160297797
    Abstract: The present invention provides compounds of Formula (I): (Formula (I), or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.
    Type: Application
    Filed: November 15, 2013
    Publication date: October 13, 2016
    Inventors: Bruce A. Ellsworth, Jun Shi, William R. Ewing, Elizabeth A. Jurica, Andres S. Hernandez, Ximao Wu, Zhengxiang Gu, Zhenqiu Hong, Stephen P. O'Connor
  • PYRROLIDINE GPR40 MODULATORS
    Publication number: 20160280680
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.
    Type: Application
    Filed: November 15, 2013
    Publication date: September 29, 2016
    Inventors: Bruce A. Ellsworth, Elizabeth A. Jurica, Jun Shi, William R. Ewing, Xiang-Yang Ye, Ximao Wu, Zhu Yeheng, Sun Chongqing
  • PYRROLIDINE GPR40 MODULATORS
    Publication number: 20150322044
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, a tautomer, a pharmaceutically acceptable salt, a polymorph, or a solvate thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.
    Type: Application
    Filed: May 6, 2015
    Publication date: November 12, 2015
    Inventors: Elizabeth A. Jurica, Zhenqiu Hong
  • Dihydropyrazole GPR40 modulators
    Patent number: 9133163
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.
    Type: Grant
    Filed: November 15, 2013
    Date of Patent: September 15, 2015
    Assignee: Bristol-Myers Squibb Company
    Inventors: Bruce A. Ellsworth, Jun Shi, William R. Ewing, Elizabeth A. Jurica, Andres S. Hernandez, Ximao Wu
  • DIHYDROPYRAZOLE GPR40 MODULATORS
    Publication number: 20140142139
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.
    Type: Application
    Filed: November 15, 2013
    Publication date: May 22, 2014
    Inventors: Bruce A. Ellsworth, Jun Shi, William R. Ewing, Elizabeth A. Jurica, Andres S. Hernandez, Ximao Wu
  • Pyrrolidine GPR40 modulators
    Patent number: 8288404
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.
    Type: Grant
    Filed: October 5, 2010
    Date of Patent: October 16, 2012
    Assignee: Bristol-Myers Squibb Company
    Inventors: Bruce A. Ellsworth, William R. Ewing, Elizabeth Jurica
  • PYRROLIDINE GPR40 MODULATORS
    Publication number: 20110082165
    Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.
    Type: Application
    Filed: October 5, 2010
    Publication date: April 7, 2011
    Inventors: Bruce A. Ellsworth, William R. Ewing, Elizabeth Jurica