Patents by Inventor Elizabeth A. Malloy

Elizabeth A. Malloy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Acetylenic compounds useful in treating inflammatory disorders
    Patent number: 7476672
    Abstract: This invention is directed to acetylenic compounds as inhibitors of a nicotinamide adenine dinucleotide oxidase hydride donor useful in treating or ameliorating a reactive oxygen species mediated inflammatory disorder.
    Type: Grant
    Filed: January 10, 2006
    Date of Patent: January 13, 2009
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Scott Beers, Elizabeth A. Malloy, Michael P. Wachter
  • Acetylenic compounds useful in treating inflammatory disorders
    Patent number: 7338952
    Abstract: This invention is directed to acetylenic compounds as inhibitors of a nicotinamide adenine dinucleotide oxidase hydride donor useful in treating or ameliorating a reactive oxygen species mediated inflammatory disorder.
    Type: Grant
    Filed: January 10, 2006
    Date of Patent: March 4, 2008
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Scott Beers, Elizabeth A. Malloy, Michael P. Wachter
  • Acetylenic compounds useful in treating inflammatory disorders
    Publication number: 20060111352
    Abstract: This invention is directed to acetylenic compounds as inhibitors of a nicotinamide adenine dinucleotide oxidase hydride donor useful in treating or ameliorating a reactive oxygen species mediated inflammatory disorder.
    Type: Application
    Filed: January 10, 2006
    Publication date: May 25, 2006
    Inventors: Scott Beers, Elizabeth Malloy, Michael Wachter
  • Acetylenic compounds useful in treating inflammatory disorders
    Publication number: 20060106018
    Abstract: This invention is directed to acetylenic compounds as inhibitors of a nicotinamide adenine dinucleotide oxidase hydride donor useful in treating or ameliorating a reactive oxygen species mediated inflammatory disorder.
    Type: Application
    Filed: January 10, 2006
    Publication date: May 18, 2006
    Inventors: Scott Beers, Elizabeth Malloy, Michael Wachter
  • Acetylenic compound useful in treating inflammatory disorders
    Patent number: 7022703
    Abstract: This invention is directed to acetylenic compounds as inhibitors of a nicotinamide adenine dinucleotide oxidase hydride donor useful in treating or ameliorating a reactive oxygen species mediated inflammatory disorder.
    Type: Grant
    Filed: July 24, 2003
    Date of Patent: April 4, 2006
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Scott Beers, Elizabeth A. Malloy, Michael P. Wachter
  • Acetylenic compound useful in treating inflammatory disorders
    Publication number: 20050020838
    Abstract: This invention is directed to acetylenic compounds as inhibitors of a nicotinamide adenine dinucleotide oxidase hydride donor useful in treating or ameliorating a reactive oxygen species mediated inflammatory disorder.
    Type: Application
    Filed: July 24, 2003
    Publication date: January 27, 2005
    Inventors: Scott Beers, Elizabeth Malloy, Michael Wachter
  • Substituted imidazoles useful in the treatment of inflammatory diseases
    Patent number: 6521655
    Abstract: This invention relates to a series of substituted imidazoles of Formula I pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention inhibit the production of a number of inflammatory cytokines, and are useful in the treatment of diseases associated with overproduction of inflammatory cytokines.
    Type: Grant
    Filed: November 3, 2000
    Date of Patent: February 18, 2003
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Scott A. Beers, Elizabeth A. Malloy, Michael P. Wachter, Wei Wu
  • Substituted imidazoles useful in the treatment of inflammatory diseases
    Patent number: 6214830
    Abstract: This invention relates to a series of substituted imidazoles of Formula I pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention inhibit the production of a number of inflammatory cytokines, and are useful in the treatment of diseases associated with overproduction of inflammatory cytokines.
    Type: Grant
    Filed: April 20, 1999
    Date of Patent: April 10, 2001
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Scott A. Beers, Elizabeth A. Malloy, Michael P. Wachter, Wei Wu
  • 2-substituted imidazoles useful in the treatment of inflammatory diseases
    Patent number: 6040320
    Abstract: This invention relates to substituted imidazoles of Formula I ##STR1## pharmaceutical compositions containing them, methods of using them and intermediates useful in their manufacture. The compounds of the invention modulate the production of a number of inflammatory cytokines, and are useful in the treatment of diseases associated with the production of inflammatory cytokines.
    Type: Grant
    Filed: June 29, 1998
    Date of Patent: March 21, 2000
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Scott A. Beers, Elizabeth A. Malloy, Michael P. Wachter, Wei Wu
  • Arylmethylphosphonic acid derivatives useful in treating bone wasting diseases
    Patent number: 5994563
    Abstract: Benzyl-phosphonate compounds represented by the formula I: ##STR1## are disclosed as useful in treating bone wasting diseases and as an immunosuppresant.
    Type: Grant
    Filed: January 19, 1999
    Date of Patent: November 30, 1999
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Scott Beers, Roger F. Frechette, Elizabeth A. Malloy, Charles Schwender, Wei Wu
  • Substituted imidazoles useful in the treatment of inflammatory disease
    Patent number: 5965583
    Abstract: This invention relates to a series of substituted imidazoles of Formula I ##STR1## pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention inhibit the production of a number of inflammatory cytokines, and are useful in the treatment of diseases associated with overproduction of inflammatory cytokines.
    Type: Grant
    Filed: April 17, 1998
    Date of Patent: October 12, 1999
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Scott A. Beers, Elizabeth A. Malloy, Michael P. Wachter, Wei Wu
  • Substituted phosphonic acids and derivatives useful in treating bone wasting diseases
    Patent number: 5508273
    Abstract: Compounds represented by the formula I: ##STR1## are disclosed as agents for use in treating bone wasting diseases.
    Type: Grant
    Filed: December 30, 1993
    Date of Patent: April 16, 1996
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Scott Beers, Elizabeth A. Malloy, Charles Schwender