Abstract: This invention relates to a polyester composition comprising: (1) at least one polyester which comprises: (a) a dicarboxylic acid component comprising: (i) about 70 to about 100 mole % residues of terephthalic acid or esters thereof; (ii) about 0 to about 30 mole % of aromatic and/or aliphatic dicarboxylic acid residues having up to 20 carbon atoms; (b) a glycol component comprising: (i) about 10 to about 50 mole % of 2,2,4,4-tetramethyl-1,3-cyclobutanediol residues; (ii) about 50 to about 90 mole % residues of 1,4-cyclohexanedimethanol; wherein the total mole % of the dicarboxylic acid component is 100 mole %, wherein the total mole % of the diol component is 100 mole %; and (2) lithium atoms, gallium atoms, and less than 30 ppm, or less than 20 ppm, or less than 10 ppm, or less than 5 ppm, or less than 2 ppm, or from 0 to 30 ppm, or from 0 to 20 ppm, or from 0 to 10 ppm, or 0 ppm of tin atoms.

Abstract: A polyester composition comprising: (1) at least one polyester which comprises: (a) a dicarboxylic acid component comprising: (i) about 70 to about 100 mole % residues of terephthalic acid or esters thereof; (ii) about 0 to about 30 mole % of aromatic and/or aliphatic dicarboxylic acid residues having up to 20 carbon atoms; (b) a glycol component comprising: (i) about 10 to about 60 mole % of 2, 2,4,4-tetramethyl-1,3-cyclobutanediol residues; (ii) about 40 to about 90 mole % residues of 1,4-cyclohexanedimethanol; (iii) optionally, residues of at least one modifying glycol; wherein the total mole % of the dicarboxylic acid component of the final polyester is 100 mole %; wherein the total mole % of the glycol component of the final polyester is 100 mole %; and (2) residues comprising titanium atoms and zinc atoms, and less than 30 ppm, or less than 20 ppm, or less than 10 ppm, or less than 5 ppm, or less than 2 ppm, or from 0 to 30 ppm, or from 0 to 20 ppm, or from 0 to 10 ppm, or 0 ppm of tin atoms.

Abstract: This invention relates to a polyester composition comprising: (1) at least one polyester which comprises: (a) a dicarboxylic acid component comprising: (i) about 70 to about 100 mole % residues of terephthalic acid or esters thereof; (ii) about 0 to about 30 mole % of aromatic and/or aliphatic dicarboxylic acid residues having up to 20 carbon atoms; (b) a glycol component comprising: (i) about 10 to about 50 mole % of 2,2,4,4-tetramethyM,3-cyclobutanediol residues; (ii) about 50 to about 90 mole % residues of modifying glycols; wherein the total mole % of the dicarboxylic acid component is 100 mole %, wherein the total mole % of the diol component is 100 mole %; and (2) lithium atoms, gallium atoms; and, optionally, less than 30 ppm, or less than 20 ppm, or less than 10 ppm, or less than 5 ppm, or less than 2 ppm, or from 0 to 30 ppm, or from 0 to 20 ppm, or from 0 to 10 ppm, or 0 ppm of tin atoms.

Abstract: Sensors are disclosed that detect whether a cannula is properly inserted to its full depth in a subject's skin. The sensors may be used with a blood glucose monitor, or with a continuous insulin infusion pump, infusion set, or other system involving intermittent or continuous testing and/or drug delivery.

Abstract: An example of a system for monitoring and treating respiratory distress in a patient may include one or more non-invasive monitoring devices to acquire patient condition signals and a respiratory distress monitoring circuit to monitor a state of the respiratory distress using the patient condition signals. The respiratory distress monitoring circuit may include a signal processing circuit to generate patient condition parameters using the patient condition signals and a respiratory distress analyzer, which may include a parameter analysis circuit and a notification circuit. The parameter analysis circuit may be configured to produce a patient condition metric being a function of the patient condition parameters and to perform prediction and/or detection of an exacerbation of the respiratory distress based on the patient condition metric. The notification circuit may be configured to produce an alert notifying a result of the performance of the prediction and/or detection.

Abstract: The disclosure provides methods and systems for determining an emotional fitness metrics for users. A physiological parameter of the user is measured during a group activity using at least one biosensor to acquire a measured signal. The measured signal of the user is compared to a measured signal for the physiological parameter of one or more additional users as measured when the one or more additional users perform the group activity. An emotional connectivity may be calculated based on a synchronicity of the measured signal of the user with the measured signal of the one or more additional users, as well as a cognitive appraisal metric, a resilience metric and an emotional fitness metric. Connectivity values for user pairings for a group activity can be computed based a synchronicity in a time-series correlation for the physiological parameters for permutations of the user pairings for the group activity.

Abstract: This invention relates to a polyester composition comprising: (1) at least one polyester which comprises: (a) a dicarboxylic acid component comprising: (i) about 70 to about 100 mole % residues of terephthalic acid or esters thereof; (ii) about 0 to about 30 mole % of aromatic and/or aliphatic dicarboxylic acid residues having up to 20 carbon atoms; (b) a glycol component comprising: (i) about 10 to about 50 mole % of 2,2,4,4-tetramethyl-1,3-cyclobutanediol residues; (ii) about 50 to about 90 mole % residues of modifying glycols; wherein the total mole % of the dicarboxylic acid component is 100 mole %, wherein the total mole % of the diol component is 100 mole %; and (2) residues of a catalyst system comprising lithium atoms, aluminum atoms, and, optionally, less than 30 ppm, or less than 20 ppm, or less than 10 ppm, or less than 5 ppm, or from 0 to 30 ppm, or from 0 to 20 ppm, or from 0 to 10 ppm, or 0 ppm of tin atoms, relative to the mass of final polyester being prepared.

Abstract: This invention relates to a polyester composition comprising: (1) at least one polyester which comprises: (a) a dicarboxylic acid component comprising: (i) about 70 to about 100 mole % residues of terephthalic acid or esters thereof; (ii) about 0 to about 30 mole % of aromatic and/or aliphatic dicarboxylic acid residues having up to 20 carbon atoms; (b) a glycol component comprising: (i) about 10 to about 50 mole % of 2,2,4,4-tetramethyl-1,3-cyclobutanediol residues; (ii) about 50 to about 90 mole % residues of modifying glycols; wherein the total mole % of the dicarboxylic acid component of the final polyester is 100 mole %; wherein the total mole % of the glycol component of the final polyester is 100 mole %; and (2) residues comprising titanium atoms and zinc atoms, and less than 30 ppm, or less than 20 ppm, or less than 10 ppm, or less than 5 ppm, or less than 2 ppm, or from 0 to 30 ppm, or from 0 to 20 ppm, or from 0 to 10 ppm, or 0 ppm of tin atoms.

Abstract: This invention relates to a process for making at least one polyester comprising: (a) a dicarboxylic acid component comprising: (i) 70 to 100 mole % of terephthalic acid residues; (ii) 0 to 30 mole % of aromatic dicarboxylic acid residues having up to 20 carbon atoms; and (iii) 0 to 10 mole % of aliphatic dicarboxylic acid residues having up to 16 carbon atoms; (b) a glycol component comprising: (i) 10 to 50 mole % of 2,2,4,4-tetramethyl-1,3-cyclobutanediol residues, which is a combination of greater than 80 mole % of cis-2,2,4,4-tetramethyl-1,3-cyclobutanediol and less than 20 mole % of trans-2,2,4,4-tetramethyl-1,3-cyclobutanediol, or greater than 85 mole % of cis-2, 2,4,4-tetramethyl-1,3-cyclobutanediol and less than 15 mole % of trans-2,2,4,4-tetramethyl-1,3-cyclobutanediol, or greater than 90 mole % of cis-2,2,4,4-tetramethyl-1,3-cyclobutanediol and less than 10 mole % of trans-2,2,4,4-tetramethyl-1,3-cyclobutanediol, or greater than 95 mole % of cis-2, 2,4,4-tetramethyl-1,3-cyclobutanediol and less than

Abstract: The present invention relates to a combination comprising a Treg depletor and an LTBR agonist. Such a combination is particularly useful for use in the treatment of a cancer.

Abstract: This invention relates to a polyester composition comprising: (1) at least one polyester which comprises: (a) a dicarboxylic acid component comprising: (i) about 70 to about 100 mole % residues of terephthalic acid or esters thereof; (ii) about 0 to about 30 mole % of aromatic and/or aliphatic dicarboxylic acid residues having up to 20 carbon atoms; (b) a glycol component comprising: (i) about 10 to about 50 mole % of 2, 2,4,4-tetramethyl-1,3-cyclobutanediol residues; (ii) about 50 to about 90 mole % of 1,4-cyclohexanedimethanol residues; wherein the total mole % of the dicarboxylic acid component is 100 mole %, wherein the total mole % of the diol component is 100 mole %; and (2) residues of a catalyst system comprising lithium atoms, aluminum atoms, and less than 30 ppm, or less than 20 ppm, or less than 10 ppm, or less than 5 ppm, or less than 2 ppm, or from 0 to 30 ppm, or from 0 to 20 ppm, or from 0 to 10 ppm, or 0 ppm tin atoms.

Abstract: The window assembly of the present invention includes a window frame and window sash rotatable relative to the window frame between a closed position and an open position. In the closed position, the window sash is positioned parallel to the window frame. In the open position, a space is defined between the bottom edges of the window frame and the window sash, and the space defined between the side edges of the window frame and the window sash. A window screen is connected to the two side edges and the bottom edge of the window sash, the two side edges and the bottom edge of the window frame. The window screen is configured to extend in the space. The viewer can have a clear view out of the window assembly without the unsightliness, distortion, or sunlight blockage that is caused by conventional “always visible” window screens.

Abstract: Indole derivatives as alpha-1-antitrypsin modulators for treating alpha-1-antitrypsin deficiency (AATD).

Abstract: 1H-pyrazolo[4,3-g]isoquinoline and 1H-pyrazolo[4,3-g]quinoline derivatives as alpha-1-antitrypsin modulators for treating alpha-1-antitrypsin deficiency (AATD).

Abstract: Systems and methods for allocating resources. The system includes a communications module, a processor, and a memory. The memory stores a data record and instructions that, when executed, configure the processor to obtain a data record and transmit an existing score indication corresponding to the data record for display at the client device; receive a first time parameter and an action indicator associated with a shared resource and, in response, determine a first provisional score corresponding to the data record based on the existing score indication, the action indicator, and the first time parameter to provide a first provisional score indication; transmit the first provisional score indication and a selectable option associated with the action indicator for display at the client device while the first provisional score indication is displayed; and in response to receiving a resource transfer instruction, allocate the shared resource associated with the action indicator.

Abstract: The present invention relates to humanized antibodies that specifically bind to CXCR5 and can, for example, inhibit CXCR5 function. The invention also includes uses of the antibodies to treat or prevent CXCR5 related diseases or disorders.

Abstract: The present disclosure relates to articles for transmitting and/or receiving radio waves therethrough having a frequency in the range of 0.5 GHz to 81 GHz. The recyclable articles include a thermoplastic resin including a polyamide and provide low signal attenuation of the radio waves transmitted or received therethrough. The article can include a colorant dispersed in the thermoplastic resin, wherein the colorant is substantially free of metals and metal-containing compounds; the article can include a paint, ink, or colored coating on an exterior thereof, wherein the paint, ink, and colored coating are substantially free of metals and metal-containing compounds; or a combination thereof.

Abstract: Embodiments of the invention provide a method of processing colour image data comprising receiving image data corresponding to a first and a second region of an image having colour information represented in a first colour space; converting the colour information of the image data from the first colour space to a second colour space, the mapping being arranged to substantially maintain a perceived colour of the colour information and to select a meta-brightness of the first and second regions; and out putting the image data having colour information in the second colour space.

Abstract: Methods and devices for controlling display of a user interface. A computing device configured to enable data exchanges in connection with accounts, including a credit account, determines whether a requested data exchange with the credit account will result in the credit account exceeding a utilization threshold. If not, a standard interface for completing the data exchange is displayed. If the data exchange will result in exceeding the threshold, then a modified interface is displayed. The modified interface enables completion of the data exchange within a minimum time period longer than the minimum time period within which the data exchange may be completed through the standard interface. Example modifications include adding an input element or field, adding delay to display or rendering of graphics, adding pop-ups, or removing pre-populated selections or values, among others.

Abstract: Systems and methods for allocating resources. The system includes a communications module, a processor, and a memory. The memory stores a data record and instructions that, when executed, configure the processor to obtain a data record and transmit an existing score indication corresponding to the data record for display at the client device; receive a first time parameter and an action indicator associated with a shared resource and, in response, determine a first provisional score corresponding to the data record based on the existing score indication, the action indicator, and the first time parameter to provide a first provisional score indication; transmit the first provisional score indication and a selectable option associated with the action indicator for display at the client device while the first provisional score indication is displayed; and in response to receiving a resource transfer instruction, allocate the shared resource associated with the action indicator.