Abstract: Provided herein are materials and methods for detecting colorectal neoplasms and colon cancer based on the expression levels of stool-derived eukaryotic RNA biomarkers in eukaryotic nucleic acid present in a stool sample from a subject, for example, a patient. The methods can be used for the detection of high-risk adenomas and colorectal neoplasm molecular subtypes.

Abstract: Systems, methods, and computer program products for recommending ecosystem credit tokens based on modelled outcomes are provided. In various embodiments, field data comprising geospatial boundaries of one or more field are received. One or more methodology is accessed. For each of the one or more fields, one or more farming practice is accessed, wherein each farming practice comprises a location and time. For each of the one or more fields, for each crop production period, an ecosystem attribute is generated by applying one or more ecosystem attribute quantification methods to each spatially and temporally unique set of one or more farming practices. Selection of one or more program is optimized for each field based on the set of selected programs being compatible within the field and production period.

Abstract: Systems, methods, and computer program products for recommending farming practices based on modelled outcomes are provided. In various embodiments, field data comprising geospatial boundaries of one or more field are received. Management event data comprising one or more management events within the one or more fields is received. For each management event, a management event boundary defining geospatial boundaries is received, and one or more management zones is determined based on the management event boundaries. One or more ecosystem attribute quantification method is applied to each of the one or more management zones to generate one or more ecosystem attributes of the one or more management zones. One or more ecosystem attribute is selected for each management zone. An ecosystem credit token or portion thereof is generated for each selected ecosystem attribute. The ecosystem credit token is associated with a quantity of raw agricultural product.

Abstract: Systems, methods, and computer program products for maintaining a collection of ecosystem credit tokens based on modelled outcomes are provided. In various embodiments, an ecosystem attribute target profile for the collection of ecosystem credit tokens is accessed. The target profile comprises a set of ecosystem characteristics, quantities of one or more ecosystem characteristics, and permanence of one or more ecosystem characteristics. A set of ecosystem credit tokens is accessed, wherein each ecosystem credit token data record comprises one or more of: a validated and verified management event, a methodology, an ecosystem attribute, a boundary, an ecosystem impact, an ecosystem credit, and an ecosystem attribute quantification method. A current profile of the collection of ecosystem credit tokens is determined, wherein the profile comprises the set of ecosystem characteristics within the collection, quantities of ecosystem characteristics, and permanence of ecosystem characteristics.

Abstract: Systems, methods, and computer program products for recommending farming practices based on modelled outcomes are provided. In various embodiments, field data comprising geospatial boundaries of one or more field are received. Management event data comprising one or more management events within the one or more fields is received. For each management event, a management event boundary defining geospatial boundaries is received, and one or more management zones is determined based on the management event boundaries. The determination of one or more management zones comprises sequentially intersecting a geospatial boundary. Each sequential intersection operation creating two branches, one with the intersection of the geometries and one with the difference.

Abstract: Systems, methods, and computer program products for recommending farming practices based on modelled outcomes are provided. In various embodiments, field data comprising geospatial boundaries of one or more field are received. Management event data comprising one or more management events within the one or more fields is received. For each management event, a management event boundary defining geospatial boundaries is received, and one or more management zones is determined based on the management event boundaries. The determination of one or more management zones comprises sequentially intersecting a geospatial boundary. Each sequential intersection operation creating two branches, one with the intersection of the geometries and one with the difference.

Abstract: Systems, methods, and computer program products for maintaining a collection of ecosystem credit tokens based on modelled outcomes are provided. In various embodiments, an ecosystem attribute target profile for the collection of ecosystem credit tokens is accessed. The target profile comprises a set of ecosystem characteristics, quantities of one or more ecosystem characteristics, and permanence of one or more ecosystem characteristics. A set of ecosystem credit tokens is accessed, wherein each ecosystem credit token data record comprises one or more of: a validated and verified management event, a methodology, an ecosystem attribute, a boundary, an ecosystem impact, an ecosystem credit, and an ecosystem attribute quantification method. A current profile of the collection of ecosystem credit tokens is determined, wherein the profile comprises the set of ecosystem characteristics within the collection, quantities of ecosystem characteristics, and permanence of ecosystem characteristics.

Abstract: Systems, methods, and computer program products for recommending ecosystem credit tokens based on modelled outcomes are provided. In various embodiments, field data comprising geospatial boundaries of one or more field are received. One or more methodology is accessed. For each of the one or more fields, one or more farming practice is accessed, wherein each farming practice comprises a location and time. For each of the one or more fields, for each crop production period, an ecosystem attribute is generated by applying one or more ecosystem attribute quantification methods to each spatially and temporally unique set of one or more farming practices. Selection of one or more program is optimized for each field based on the set of selected programs being compatible within the field and production period.

Abstract: A mosquito agitator system and method to disrupt the development of mosquito larvae in bodies of water are disclosed. The mosquito agitator, in one embodiment, includes a motor coupled to a rotating shaft that is coupled to a non-symmetric mass; a hull coupled to the motor; one or more solar panels coupled to the hull for capturing solar energy into electricity; a plurality of sensors; and a controller coupled to at least the motor, wherein the controller is configured to receive sensor data from the plurality of sensors; select a first mosquito agitator algorithm for execution; and execute the first mosquito agitator algorithm to control activate the motor in accordance with the first mosquito agitator algorithm, wherein the activation causes the hull to create a plurality of water ripples in the body of water to disrupt the development of mosquito larvae.

Abstract: A mosquito agitator system and method to disrupt the development of mosquito larvae in bodies of water are disclosed. The mosquito agitator, in one embodiment, includes a motor coupled to a rotating shaft that is coupled to a non-symmetric mass; a hull coupled to the motor; one or more solar panels coupled to the hull for capturing solar energy into electricity; a plurality of sensors; and a controller coupled to at least the motor, wherein the controller is configured to receive sensor data from the plurality of sensors; select a first mosquito agitator algorithm for execution; and execute the first mosquito agitator algorithm to control activate the motor in accordance with the first mosquito agitator algorithm, wherein the activation causes the hull to create a plurality of water ripples in the body of water to disrupt the development of mosquito larvae.

Abstract: A method and system for the backup and recovery of a converged infrastructure computer system are provided with the ability to determine if the backup meets requirements of a disaster recovery plan. The method and system provide backup and recovery of the data and applications including backup and recovery of the configuration and mapping information of the converged infrastructure computer system. The backups are periodically tested to determine if they meet predetermined metrics that are specified in the disaster recovery plan.

Abstract: A method and system for the backup and recovery of a converged infrastructure computer system are provided with the ability to determine if the backup meets requirements of a disaster recovery plan. The method and system provide backup and recovery of the data and applications including backup and recovery of the configuration and mapping information of the converged infrastructure computer system. The backups are periodically tested to determine if they meet predetermined metrics that are specified in the disaster recovery plan.

Abstract: A heat diffuser for a teacup is provided. The diffuser is specific to traditional teacups that do not have handles and are made from cast-iron, bone, china, clay, ceramic, or similar materials. The diffuser includes multiple insulated fabric fingers that cradle the teacup to diffuse heat away from the individual holding the cup. The fingers are created by layering one or more fabric pieces and one or more insulating components. The diffuser lays flat on a surface, such as a saucer or table, until the individual engages the diffuser by lifting the diffuser and the cup causing the diffuser to cradle around the cup between the user's hand and the teacup. The diffuser is made to absorb some, but not all of the heat, so that it still allows the individual to feel some warmth.

Abstract: A method and apparatus is provided for the backup and immediate recovery of an application executing on a computer. The method and apparatus provides file level backup of a target computer executing the application. The file level backup is transformed into a bootable machine image that is accessible for immediate recovery of the application by either a virtual server executing on the apparatus or an external server or an external virtual server.

Abstract: A detailed three-dimensional structure for a bacterial core RNA polymerase is provided. Crystals of the bacterial core RNA polymerase are also included in the invention. The present invention further provides procedures for identifying agents that can inhibit bacterial proliferation through the use of rational drug design predicated on the crystals and crystallographic data disclosed.

Abstract: The present invention addresses the use of substituted thiophene derivatives, as well as compositions containing such compounds for treating type 2 diabetes mellitus. The compounds in the present invention are glucagon antagonists. The compounds block the action of glucagon at its receptor and thereby decrease the levels of plasma glucose providing a treatment of diabetes.

Abstract: Method and system for generating a report for use in buyer/supplier negotiations for purchasing a commodity. Embodiments include collecting data to define the technical capabilities of two or more suppliers to supply a commodity to a buyer, collecting data to define attributes of the commodity and the commodity market, and collecting data from the selected suppliers to identify their relative competitive position. Collected data is input into a computer configured to process at least a portion of the collected data and output a consolidated report for use in negotiations. Opportunities for improving supplier competitive position may be identified. During buyer/supplier negotiation, a supplier may be encouraged or required to (i) adopt one or more of the competitive opportunities identified in the strategy report or (ii) agree to adjusted contract terms in compensation for not adopting one or more of the competitive opportunities illustrated in the strategy report.

Abstract: The present invention addresses substituted thiophene derivatives, as well as compositions containing such compounds and methods of treatment. The compounds in the present invention are glucagon antagonists. The compounds block the action of glucagon at its receptor and thereby decrease the levels of plasma glucose providing a treatment of diabetes.

Abstract: A detailed three-dimensional structure of rifampicin bound to a core bacterial RNA polymerase (Rif-RNAP) is provided. Crystals of the Rif-RNAP are also included in the invention. The present invention further provides procedures for identifying agents that can inhibit bacterial proliferation through the use of rational drug design predicated on the crystals and crystallographic data disclosed.

Abstract: A detailed three-dimensional structure of rifampicin bound to a core bacterial RNA polymerase (Rif-RNAP) is provided. Crystals of the Rif-RNAP are also included in the invention. The present invention further provides procedures for identifying agents that can inhibit bacterial proliferation through the use of rational drug design predicated on the crystals and crystallographic data disclosed.