Patents by Inventor Elizabeth Chu

Elizabeth Chu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MicroRNA and inhibitors thereof and methods of treatment
    Patent number: 11965162
    Abstract: In one aspect, compositions are provided for the early diagnosis and treatment of pancreatic ductal adenocarcinoma and include microRNAs, e.g. miR-21 and inhibitors thereof. The treatment compositions can be useful for early detection, and for intercepting developing premalignant pancreatic lesions and other KRAS-driven premalignancies.
    Type: Grant
    Filed: April 16, 2021
    Date of Patent: April 23, 2024
    Assignee: The Johns Hopkins University
    Inventors: Elizabeth A. Jaffee, Nina Chu, Jacquelyn Winifred Zimmerman
  • SPRAY-DRIED FORMULATION OF A PYRIDAZINONE TRPC5 INHIBITOR
    Publication number: 20220183981
    Abstract: Disclosed are spray-dried formulations of 4-chloro-5-(4-(4-fluoro-2-(trifluoromethyl)phenoxy)-5,8-dihydropyrido[3,4-d]pyrimidin-7(6H)-yl)pyridazin-3(2H)-one, methods and compositions for making the same, and solid dosage forms comprising the same. The dosage forms described herein are useful in methods of treating kidney diseases or neuropathies associated with diseases or conditions, and in methods of treating pain, anxiety, or depression.
    Type: Application
    Filed: April 10, 2020
    Publication date: June 16, 2022
    Inventors: Donald T. Corson, Elizabeth Chu Kwong, Thomas E. Stumpfig, Daniel T. Smithey, Erica B. Schlesinger
  • Thermal insulation assemblies and methods for fabricating the same
    Patent number: 8357258
    Abstract: Thermal insulation assemblies, methods for fabricating thermal insulation assemblies, and thermally insulated structures are provided. In an exemplary embodiment, a thermally insulated structure is disclosed that includes a thermal insulation assembly comprises a ceramic tile having a surface coated with an alumina-mullite slurry. A ceramic matrix composite is disposed on the coated surface. The ceramic matrix composite comprises a first ply of a ceramic fiber impregnated with a ceramic matrix.
    Type: Grant
    Filed: January 4, 2011
    Date of Patent: January 22, 2013
    Assignee: The Boeing Company
    Inventors: Vann Heng, Robert A. DiChiara, Jr., Elizabeth Chu, Dave Zorger
  • Reworking ceramic structures
    Patent number: 8252131
    Abstract: A method for reworking a ceramic structure. A number of holes are formed in a portion of the ceramic structure in which a rework of the ceramic structure is desired. The ceramic structure has a plurality of layers in the portion in which the rework is desired. A ceramic bonding material is introduced into the number of holes formed in the portion of the ceramic structure. The ceramic bonding material is cured in the portion of the ceramic structure.
    Type: Grant
    Filed: July 2, 2009
    Date of Patent: August 28, 2012
    Assignee: The Boeing Company
    Inventors: Vann Heng, Elizabeth Chu, Van H. Ngo, Larry D. King
  • THERMAL INSULATION ASSEMBLIES AND METHODS FOR FABRICATING THE SAME
    Publication number: 20110171442
    Abstract: Thermal insulation assemblies, methods for fabricating thermal insulation assemblies, and thermally insulated structures are provided. In an exemplary embodiment, a thermally insulated structure is disclosed that includes a thermal insulation assembly comprises a ceramic tile having a surface coated with an alumina-mullite slurry. A ceramic matrix composite is disposed on the coated surface. The ceramic matrix composite comprises a first ply of a ceramic fiber impregnated with a ceramic matrix.
    Type: Application
    Filed: January 4, 2011
    Publication date: July 14, 2011
    Applicant: THE BOEING COMPANY
    Inventors: Vann HENG, Robert A. DiChiara, JR., Elizabeth CHU, Dave ZORGER
  • Thermal insulation assemblies and methods for fabricating the same
    Patent number: 7887937
    Abstract: Thermal insulation assemblies and methods for fabricating thermal insulation assemblies are provided. In an exemplary embodiment, a thermal insulation assembly comprises a ceramic tile having a surface coated with an alumina-mullite slurry. A ceramic matrix composite is disposed on the coated surface. The ceramic matrix composite comprises a first ply of a ceramic fiber impregnated with a ceramic matrix.
    Type: Grant
    Filed: April 18, 2007
    Date of Patent: February 15, 2011
    Assignee: The Boeing Company
    Inventors: Vann Heng, Robert A. DiChiara, Jr., Elizabeth Chu, Dave Zorger
  • Reworking Ceramic Structures
    Publication number: 20110003077
    Abstract: A method for reworking a ceramic structure. A number of holes are formed in a portion of the ceramic structure in which a rework of the ceramic structure is desired. The ceramic structure has a plurality of layers in the portion in which the rework is desired. A ceramic bonding material is introduced into the number of holes formed in the portion of the ceramic structure. The ceramic bonding material is cured in the portion of the ceramic structure.
    Type: Application
    Filed: July 2, 2009
    Publication date: January 6, 2011
    Applicant: THE BOEING COMPANY
    Inventors: Vann Heng, Elizabeth Chu, Van H. Ngo, Larry D. King
  • Oxide-based ceramic matrix composites
    Publication number: 20100081556
    Abstract: An oxide-based ceramic matrix composite and a method of making oxide-based ceramic composite are provided. The oxide-based ceramic matrix composite comprises a ceramic fiber and a mullite-alumina impregnating the ceramic fiber, wherein the mullite-alumina ceramic matrix comprises of 10-70 wt % mullite-alumina mixture.
    Type: Application
    Filed: July 21, 2006
    Publication date: April 1, 2010
    Inventors: Vann Heng, Robert A. DiChiara, JR., Susan Saragosa, Elizabeth Chu, Carlos G. Levi, Frank W. Zok
  • THERMAL INSULATION ASSEMBLIES AND METHODS FOR FABRICATING THE SAME
    Publication number: 20080176020
    Abstract: Thermal insulation assemblies and methods for fabricating thermal insulation assemblies are provided. In an exemplary embodiment, a thermal insulation assembly comprises a ceramic tile having a surface coated with an alumina-mullite slurry. A ceramic matrix composite is disposed on the coated surface. The ceramic matrix composite comprises a first ply of a ceramic fiber impregnated with a ceramic matrix.
    Type: Application
    Filed: April 18, 2007
    Publication date: July 24, 2008
    Inventors: Vann Heng, Robert A. DiChiara, Elizabeth Chu, Dave Zorger