Patents by Inventor Elizabeth E. Murray

Elizabeth E. Murray has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8986982
    Abstract: A thermal cycle system and method suitable for mass production of DNA comprising a temperature control body having at least two sectors. Each sector has at least one heater, cooler, or other means for changing temperature. A path traverses the sectors in a cyclical fashion. In use, a piece of tubing or other means for conveying is placed along the path and a reaction mixture is pumped or otherwise moved along the path such that the reaction mixture is repetitively heated or cooled to varying temperatures as the reaction mixture cyclically traverses the sectors. The reaction mixture thereby reacts to form a product. In particular, polymerase chain reaction reactants may continuously be pumped through the tubing to amplify DNA. The temperature control body is preferably a single aluminum cylinder with a grooved channel circling around its exterior surface, and preferably has wedge-shaped or pie-shaped sectors separated by a thermal barrier.
    Type: Grant
    Filed: September 19, 2012
    Date of Patent: March 24, 2015
    Assignee: Marshall University Research Corporation
    Inventors: Derek A. Gregg, Elizabeth E. Murray, Michael L. Norton, Justin T. Swick, Herbert Tesser
  • Patent number: 8293471
    Abstract: A thermal cycle system and method suitable for mass production of DNA comprising a temperature control body having at least two sectors. Each sector has at least one heater, cooler, or other means for changing temperature. A path traverses the sectors in a cyclical fashion. In use, a piece of tubing or other means for conveying is placed along the path and a reaction mixture is pumped or otherwise moved along the path such that the reaction mixture is repetitively heated or cooled to varying temperatures as the reaction mixture cyclically traverses the sectors. The reaction mixture thereby reacts to form a product. In particular, polymerase chain reaction reactants may continuously be pumped through the tubing to amplify DNA. The temperature control body is preferably a single aluminum cylinder with a grooved channel circling around its exterior surface, and preferably has wedge-shaped or pie-shaped sectors separated by a thermal barrier.
    Type: Grant
    Filed: January 28, 2005
    Date of Patent: October 23, 2012
    Assignee: Marshall University Research Corporation
    Inventors: Derek A. Gregg, Elizabeth E. Murray, Michael L. Norton, Justin T. Swick, Herbert Tesser
  • Publication number: 20090325234
    Abstract: A thermal cycle system and method suitable for mass production of DNA comprising a temperature control body having at least two sectors. Each sector has at least one heater, cooler, or other means for changing temperature. A path traverses the sectors in a cyclical fashion. In use, a piece of tubing or other means for conveying is placed along the path and a reaction mixture is pumped or otherwise moved along the path such that the reaction mixture is repetitively heated or cooled to varying temperatures as the reaction mixture cyclically traverses the sectors. The reaction mixture thereby reacts to form a product. In particular, polymerase chain reaction reactants may continuously be pumped through the tubing to amplify DNA. The temperature control body is preferably a single aluminum cylinder with a grooved channel circling around its exterior surface, and preferably has wedge-shaped or pie-shaped sectors separated by a thermal barrier.
    Type: Application
    Filed: January 28, 2005
    Publication date: December 31, 2009
    Inventors: Derek A. Gregg, Elizabeth E. Murray, Michael L. Norton, Justin T. Swick, Herbert Tesser
  • Patent number: 6015891
    Abstract: Synthetic Baccilus thuringiensis toxin genes designed to be expressed in plants at a level higher than naturally-occurring Bt genes are provided. These genes utilize codons preferred in highly expressed monocot or dicot proteins.
    Type: Grant
    Filed: August 29, 1996
    Date of Patent: January 18, 2000
    Assignee: Mycogen Plant Science, Inc.
    Inventors: Michael J. Adang, Elizabeth E. Murray
  • Patent number: 6013523
    Abstract: Synthetic Baccilus thuringiensis toxin genes designed to be expressed in plants at a level higher than naturally-occurring Bt genes are provided. These genes utilize codons preferred in highly expressed monocot or dicot proteins.
    Type: Grant
    Filed: August 29, 1996
    Date of Patent: January 11, 2000
    Assignee: Mycogen Plant Science, Inc.
    Inventors: Michael J. Adang, Elizabeth E. Murray
  • Patent number: 5567600
    Abstract: Synthetic Baccilus thuringiensis toxin genes designed to be expressed in plants at a level higher than naturally-occurring Bt genes are provided. These genes utilize codons preferred in highly expressed monocot or dicot proteins.
    Type: Grant
    Filed: January 6, 1995
    Date of Patent: October 22, 1996
    Assignee: Mycogen Plant Sciences, Inc.
    Inventors: Michael J. Adang, Thomas A. Rocheleau, Donald J. Merlo, Elizabeth E. Murray
  • Patent number: 5567862
    Abstract: Synthetic Bacillus thuringiensis toxin genes designed to be expressed in plants at a level higher than naturally-occurring Bt genes are provided. These genes utilize codons preferred in highly expressed monocot or dicot proteins.
    Type: Grant
    Filed: January 6, 1995
    Date of Patent: October 22, 1996
    Assignee: Mycogen Plant Sciences, Inc.
    Inventors: Michael J. Adang, Thomas A. Rocheleau, Donald J. Merlo, Elizabeth E. Murray
  • Patent number: 5391487
    Abstract: A restriction endonuclease is provided. The enzyme, designated SgfI, recognizes the DNA sequence ##STR1## and cleaves the DNA sequence at a position indicated by the arrows and is preferably obtainable from microorganisms of the genus Streptomyces.
    Type: Grant
    Filed: August 13, 1993
    Date of Patent: February 21, 1995
    Assignee: Promega Corporation
    Inventors: James R. Kappelman, Raymond J. Williams, Elizabeth E. Murray, Nadia I. Vesselinova
  • Patent number: 5380831
    Abstract: Synthetic Bacillus thuringiensis toxin genes designed to be expressed in plants at a level higher than naturally-occurring Bt genes are provided. These genes utilize codons preferred in highly expressed monocot or dicot proteins.
    Type: Grant
    Filed: May 3, 1993
    Date of Patent: January 10, 1995
    Assignee: Mycogen Plant Science, Inc.
    Inventors: Michael J. Adang, Thomas A. Rocheleau, Donald J. Merlo, Elizabeth E. Murray