Abstract: A wearable assembly is configured to generate electrical pulses for transmission to an implanted tissue stimulator. The wearable assembly includes a wearable docking device, a plug-in device configured to mate with the wearable docking device, and a pulse generation module. The pulse generation module includes first internal electronics configured to generate the electrical pulses and located within the wearable docking device or within the plug-in device and second internal electronics providing a power source for the first internal electronics and located within the wearable docking device or within the plug-in device. The wearable assembly further includes a pulse transmission cable for transmitting the electrical pulses to a transmission antenna positioned adjacent the implanted tissue stimulator.

Abstract: A wearable device for facilitating neurophysiological treatment of a patient harboring an implanted neural stimulator is provided. The wearable device includes a transmitting antenna configured to accept one or more input signals and to transmit one or more electromagnetic signals to a neural stimulator that is implanted in a patient's body. The wearable device further includes a control circuitry configured to provide the one or more input signals to the transmitting antenna. The wearable device further includes a battery that provides electrical power to at least the control circuitry. The wearable device is configured to be worn outside the patient's body.

Abstract: A wearable assembly is configured to generate electrical pulses for transmission to an implanted tissue stimulator. The wearable assembly includes a wearable docking device, a plug-in device configured to mate with the wearable docking device, and a pulse generation module. The pulse generation module includes first internal electronics configured to generate the electrical pulses and located within the wearable docking device or within the plug-in device and second internal electronics providing a power source for the first internal electronics and located within the wearable docking device or within the plug-in device. The wearable assembly further includes a pulse transmission cable for transmitting the electrical pulses to a transmission antenna positioned adjacent the implanted tissue stimulator.

Abstract: Described herein are cassettes and methods for using these cassettes for cryopreserving biomaterials (e.g., a bioengineered construct or natural tissue sample) by vitrification while reducing or preventing the loss of viability associated with conventional preservation methods.

Abstract: A wearable device for facilitating neurophysiological treatment of a patient harboring an implanted neural stimulator is provided. The wearable device includes a transmitting antenna configured to accept one or more input signals and to transmit one or more electromagnetic signals to a neural stimulator that is implanted in a patients body. The wearable device further includes a control circuitry configured to provide the one or more input signals to the transmitting antenna. The wearable device further includes a battery that provides electrical power to at least the control circuitry. The wearable device is configured to be worn outside the patient's body.

Abstract: A wearable assembly is configured to generate electrical pulses for transmission to an implanted tissue stimulator. The wearable assembly includes a wearable docking device, a plug-in device configured to mate with the wearable docking device, and a pulse generation module. The pulse generation module includes first internal electronics configured to generate the electrical pulses and located within the wearable docking device or within the plug-in device and second internal electronics providing a power source for the first internal electronics and located within the wearable docking device or within the plug-in device. The wearable assembly further includes a pulse transmission cable for transmitting the electrical pulses to a transmission antenna positioned adjacent the implanted tissue stimulator.

Abstract: A wearable device for facilitating neurophysiological treatment of a patient harboring an implanted neural stimulator is provided. The wearable device includes a transmitting antenna configured to accept one or more input signals and to transmit one or more electromagnetic signals to a neural stimulator that is implanted in a patients body. The wearable device further includes a control circuitry configured to provide the one or more input signals to the transmitting antenna. The wearable device further includes a battery that provides electrical power to at least the control circuitry. The wearable device is configured to be worn outside the patient's body.

Abstract: A wearable device for facilitating neurophysiological treatment of a patient harboring an implanted neural stimulator is provided. The wearable device includes a transmitting antenna configured to accept one or more input signals and to transmit one or more electromagnetic signals to a neural stimulator that is implanted in a patient's body. The wearable device further includes a control circuitry configured to provide the one or more input signals to the transmitting antenna. The wearable device further includes a battery that provides electrical power to at least the control circuitry. The wearable device is configured to be worn outside the patient's body.

Abstract: A wearable device for facilitating neurophysiological treatment of a patient harboring an implanted neural stimulator is provided. The wearable device includes a transmitting antenna configured to accept one or more input signals and to transmit one or more electromagnetic signals to a neural stimulator that is implanted in a patient's body. The wearable device further includes a control circuitry configured to provide the one or more input signals to the transmitting antenna. The wearable device further includes a battery that provides electrical power to at least the control circuitry. The wearable device is configured to be worn outside the patient's body.

Abstract: A wearable device for facilitating neurophysiological treatment of a patient harboring an implanted neural stimulator is provided. The wearable device includes a transmitting antenna configured to accept one or more input signals and to transmit one or more electromagnetic signals to a neural stimulator that is implanted in a patient's body. The wearable device further includes a control circuitry configured to provide the one or more input signals to the transmitting antenna. The wearable device further includes a battery that provides electrical power to at least the control circuitry. The wearable device is configured to be worn outside the patient's body.

Abstract: A wearable device for facilitating neurophysiological treatment of a patient harboring an implanted neural stimulator is provided. The wearable device includes a transmitting antenna configured to accept one or more input signals and to transmit one or more electromagnetic signals to a neural stimulator that is implanted in a patient's body. The wearable device further includes a control circuitry configured to provide the one or more input signals to the transmitting antenna. The wearable device further includes a battery that provides electrical power to at least the control circuitry. The wearable device is configured to be worn outside the patient's body.

Abstract: A system and method for administering the grant accountability process in which decisions are informed by objective indicators that are scaleable to the community, foundation and grantee levels. Indicator data is entered into a grant management database and objectively analyzed to inform future grant making decisions. Drillable gauges provide a visual representation of the status of each indicator. The gauges are organized into community, foundation and grantee levels to provide a snapshot of the community as a whole, the foundation, and each grantee as in various leadership agenda and priority areas.

Abstract: Polynucleotide sequences encoding eukaryotic Rrn3 polypeptides are provided. Rrn3 is a eukaryotic RNA polymerase I transcription factor. The Rrn3 polypeptides, and antibodies thereto, can be used as diagnostic tools, as therapeutic agents and to identify agonist and antagonists of Rrn3.

Abstract: Polynucleotide sequences encoding eukaryotic Rrn3 polypeptides are provided. Rrn3 is a eukaryotic RNA polymerase I transcription factor. The Rrn3 polypeptides, and antibodies thereto, can be used as diagnostic tools, as therapeutic agents and to identify agonist and antagonists of Rrn3.