Patents by Inventor Elizabeth J Lawlor

Elizabeth J Lawlor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel tig
    Publication number: 20020150956
    Abstract: The invention provides tig polypeptides and polynucleotides encoding tig polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tig polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: April 6, 2001
    Publication date: October 17, 2002
    Inventors: Martin Karl Russel Burnham, Andrew Fosberry, John Edward Hodgson, Deborah Dee Jaworski, Elizabeth J. Lawlor, Martin Rosenberg, Christopher Michael Traini, Min Wang, Judith Ward, Richard Warren
  • Member of ATP dependent protease family, clpL
    Patent number: 6447773
    Abstract: The invention provides clpL polypeptides and DNA (RNA) encoding clpL polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: October 13, 1999
    Date of Patent: September 10, 2002
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard Oakley Nicholas, Martin Karl Russel Burnham, Julie M Pratt, Martin Rosenberg, Judith M Ward, Andrew Fosberry, Elizabeth J Lawlor
  • pth
    Publication number: 20020106776
    Abstract: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: June 8, 2001
    Publication date: August 8, 2002
    Inventors: Sanjoy Biswas, Martin K. Burnham, Andrew P. Fosberry, John E. Hodgson, Elizabeth J. Lawlor, Tong Li, Damien McDevitt, Christopher Michael Traini, Martin Rosenberg, Judith Ward, Richard Lloyd Warren, Magdalena Zalacain
  • IleS
    Patent number: 6361970
    Abstract: The invention provides ileS polypeptides and DNA (RNA) encoding ileS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ileS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 12, 1999
    Date of Patent: March 26, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: James N. Brown, Elizabeth J Lawlor, Raymond W Reichard
  • Streptococcus pneumoniae isoleucyl tRNA synthetase
    Patent number: 6329168
    Abstract: The invention provides ileS polypeptides and DNA (RNA) encoding ileS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ileS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: October 17, 1997
    Date of Patent: December 11, 2001
    Assignee: SmithKline Beecham Corp.
    Inventors: James R. Brown, Deborah D. Jaworski, Elizabeth J. Lawlor, Min Wang
  • SigB
    Patent number: 6310192
    Abstract: SigB polypeptides and DNA (RNA) encoding such SigB and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such SigB for the treatment of infection, particularly bacterial infections. Antagonists against such SigB and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of SigB nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding SigB operon and for detecting the polypeptide in a host.
    Type: Grant
    Filed: September 26, 1997
    Date of Patent: October 30, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham PLC
    Inventors: Andrew P Fosberry, Elizabeth J Lawlor, Richard O Nicholas
  • Stretococcal ERS
    Patent number: 6300119
    Abstract: The invention provides gluS polypeptides and DNA (RNA) encoding gluS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gluS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: March 19, 1999
    Date of Patent: October 9, 2001
    Inventors: Deborah D. Jaworski, Elizabeth J. Lawlor, Min Wang
  • RsbV-1 from staphylococcus aureus
    Patent number: 6297358
    Abstract: RsbV-1 polypeptides and DNA (RNA) encoding such RsbV-1 and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such RsbV-1 for the treatment of infection, particularly bacterial infections. Antagonists against such RsbV-1 and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of RsbV-1 nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding SigB operon and for detecting the polypeptide in a host.
    Type: Grant
    Filed: August 23, 1999
    Date of Patent: October 2, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Andrew P Fosberry, Elizabeth J Lawlor, Richard O Nicholas
  • CysS
    Patent number: 6277965
    Abstract: The invention provides cysS polypeptides and DNA (RNA) encoding cysS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing cysS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: March 27, 2000
    Date of Patent: August 21, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: James R Brown, Elizabeth J Lawlor, Raymond W Reichard
  • pth
    Patent number: 6274361
    Abstract: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: May 18, 1998
    Date of Patent: August 14, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Sanjoy Biswas, Martin K. R. Burnham, Andrew P. Fosberry, John E Hodgson, Elizabeth J Lawlor, Tong Li, Damien McDevitt, Christopher Michael Traini, Martin Rosenberg, Judith Ward, Richard Lloyd Warren, Magdalena Zalacain
  • ClpL
    Patent number: 6274376
    Abstract: The invention provides clpL polypeptides and DNA (RNA) encoding clpL polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing clpL polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: September 4, 1997
    Date of Patent: August 14, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Raymond Winfield Reichard, Richard Oakley Nicholas, Martin Karl Russel Burnham, Julie M Pratt, Martin Rosenberg, Judith M Ward, Andrew Fosberry, Elizabeth J Lawlor
  • aspS
    Patent number: 6265188
    Abstract: The invention provides aspS polypeptides and DNA (RNA) encoding aspS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing aspS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 11, 1999
    Date of Patent: July 24, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: James R. Brown, Elizabeth J Lawlor, Raymond W Reichard
  • Tig
    Patent number: 6242249
    Abstract: The invention provides tig polypeptides and polynucleotides encoding tig polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tig polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: October 7, 1999
    Date of Patent: June 5, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham, plc
    Inventors: Martin Karl Russel Burnham, Andrew Fosberry, John Edward Hodgson, Deborah Dee Jaworski, Elizabeth J Lawlor, Martin Rosenberg, Christopher Michael Traini, Min Wang, Judith Ward, Richard Warren
  • Tig
    Patent number: 6228617
    Abstract: The invention provides tig polypeptides and polynucleotides encoding tig polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tig polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: December 15, 1999
    Date of Patent: May 8, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Martin Karl Russel Burnham, Andrew Fosberry, John Edward Hodgson, Deborah Dee Jaworski, Elizabeth J Lawlor, Martin Rosenberg, Christopher Michael Traini, Min Wang, Judith Ward, Richard Warren
  • Phenylalanyl tRNA synthetase alpha sub-unit from Chlamydia trachomatis
    Patent number: 6214595
    Abstract: The invention provides phenylalanyl tRNA synthetase (pheS) pheS polypeptides and DNA (RNA) encoding phenylalanyl tRNA synthetase (pheS) pheS polypeptides and methods for producing such polypeptides from Chlamydia trachomatis by recombinant techniques. Also provided are methods for utilizing pheS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 13, 1999
    Date of Patent: April 10, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: James R Brown, Elizabeth J Lawlor, Raymond W Reichard
  • AspS from Chlamydia trachomatis
    Patent number: 6207162
    Abstract: The invention provides aspS polypeptides and DNA (RNA) encoding aspS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing aspS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 4, 1999
    Date of Patent: March 27, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham, plc.
    Inventors: James R. Brown, Elizabeth J Lawlor, Raymond W Reichard
  • HisS from Chlamydia trachomatis
    Patent number: 6187561
    Abstract: The invention provides hisS polynucleotides which encode hisS polypeptide, polynucleotides related thereto, and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing the hisS polynucleotides and polypeptides to screen for antibacterial compounds and for the detection of pathogens.
    Type: Grant
    Filed: December 11, 1998
    Date of Patent: February 13, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: James R Brown, Elizabeth J Lawlor, Raymond W Reichard
  • Lyss
    Patent number: 6174714
    Abstract: The invention provides lysS polypeptides and DNA (RNA) encoding lysS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing lysS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: March 16, 1999
    Date of Patent: January 16, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: James R Brown, Elizabeth J Lawlor, Raymond W Reichard
  • Streptococcal ERS
    Patent number: 6165760
    Abstract: The invention provides gluS polypeptides and DNA (RNA) encoding gluS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gluS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: March 31, 1999
    Date of Patent: December 26, 2000
    Assignee: SmithKline Beecham Corporation.
    Inventors: Deborah D. Jaworski, Elizabeth J. Lawlor, Min Wang
  • Staphylococcus aureus rsbU-1
    Patent number: 6111078
    Abstract: rsbU-1 polypeptides and DNA (RNA) encoding such rsbU-1 and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such rsbU-1 for the treatment of infection, particularly bacterial infections. Antagonists against such rsbU-1 and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of rsbU-1 nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding SigB operon and for detecting the polypeptide in a host.
    Type: Grant
    Filed: June 28, 1999
    Date of Patent: August 29, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Andrew P Fosberry, Elizabeth J Lawlor, Richard O Nicholas