Patents by Inventor Elizabeth J. Zaretsky

Elizabeth J. Zaretsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microbial Trypsin Mutants having Chymotrypsin Activity And Nucleic Acids Encoding Same
    Publication number: 20120142075
    Abstract: The present invention relates to microbial trypsin variants having chymotrypsin-like activity, comprising: (a) a one or more substitutions corresponding to positions 144, S193, 198, 201, 218, 223, 227, 228, 229, 230, and 231 of amino acids 25 to 248 of SEQ ID NO: 2, (b) one or more deletions corresponding to positions 192, 197, and 226 of amino acids 25 to 248 of SEQ ID NO: 2; and (c) an insertion between positions corresponding to positions 224 and 225 of amino acids 25 to 248 of SEQ ID NO: 2. The present invention further relates to nucleotide sequences encoding microbial trypsin variants having chymotrypsin-like activity; nucleic acid constructs, expression vectors, and recombinant host cells comprising such nucleotide sequences; and methods of producing microbial trypsin variants having chymotrypsin-like activity or a precursor thereof.
    Type: Application
    Filed: February 13, 2012
    Publication date: June 7, 2012
    Applicant: Novozymes, Inc.
    Inventors: Alan Klotz, Kimberly M. Brown, Elizabeth J. Zaretsky
  • Methods for obtaining microbial trypsin mutants having chymotrypsin activity
    Patent number: 8114635
    Abstract: The present invention relates to microbial trypsin variants having chymotrypsin-like activity, comprising: (a) a one or more substitutions corresponding to positions 144, 193, 198, 201, 218, 223, 227, 228, 229, 230, and 231 of amino acids 25 to 248 of SEQ ID NO: 2, (b) one or more deletions corresponding to positions 192, 197, and 226 of amino acids 25 to 248 of SEQ ID NO: 2; and (c) an insertion between positions corresponding to positions 224 and 225 of amino acids 25 to 248 of SEQ ID NO: 2. The present invention further relates to nucleotide sequences encoding microbial trypsin variants having chymotrypsin-like activity; nucleic acid constructs, expression vectors, and recombinant host cells comprising such nucleotide sequences; and methods of producing microbial trypsin variants having chymotrypsin-like activity or a precursor thereof.
    Type: Grant
    Filed: February 18, 2010
    Date of Patent: February 14, 2012
    Assignee: Novozymes, Inc.
    Inventors: Alan Klotz, Kimberly M. Brown, Elizabeth J. Zaretsky
  • Microbial trypsin mutants having chymotrypsin activity and nucleic acids encoding same
    Publication number: 20100151515
    Abstract: The present invention relates to microbial trypsin variants having chymotrypsin-like activity, comprising: (a) a one or more substitutions corresponding to positions 144, S193A, 198, 201, 218, 223, 227, 228, 229, 230, and 231 of amino acids 25 to 248 of SEQ ID NO: 2, (b) one or more deletions corresponding to positions 192, 197, and 226 of amino acids 25 to 248 of SEQ ID NO: 2; and (c) an insertion between positions corresponding to positions 224 and 225 of amino acids 25 to 248 of SEQ ID NO: 2. The present invention further relates to nucleotide sequences encoding microbial trypsin variants having chymotrypsin-like activity; nucleic acid constructs, expression vectors, and recombinant host cells comprising such nucleotide sequences; and methods of producing microbial trypsin variants having chymotrypsin-like activity or a precursor thereof.
    Type: Application
    Filed: February 18, 2010
    Publication date: June 17, 2010
    Applicant: Novozymes, Inc.
    Inventors: Alan Klotz, Kimberly M. Brown, Elizabeth J. Zaretsky
  • Microbial trypsin mutants having chymotrypsin activity and nucleic acids encoding same
    Patent number: 7705137
    Abstract: The present invention relates to microbial trypsin variants having chymotrypsin-like activity, comprising: (a) a one or more substitutions corresponding to positions 144, S193A, 198, 201, 218, 223, 227, 228, 229, 230, and 231 of amino acids 25 to 248 of SEQ ID NO: 2, (b) one or more deletions corresponding to positions 192, 197, and 226 of amino acids 25 to 248 of SEQ ID NO: 2; and (c) an insertion between positions corresponding to positions 224 and 225 of amino acids 25 to 248 of SEQ ID NO: 2. The present invention further relates to nucleotide sequences encoding microbial trypsin variants having chymotrypsin-like activity; nucleic acid constructs, expression vectors, and recombinant host cells comprising such nucleotide sequences; and methods of producing microbial trypsin variants having chymotrypsin-like activity or a precursor thereof.
    Type: Grant
    Filed: January 30, 2008
    Date of Patent: April 27, 2010
    Assignee: Novozymes, Inc.
    Inventors: Alan Klotz, Kimberly M. Brown, Elizabeth J. Zaretsky
  • Microbial Trypsin Mutants Having Chymotrypsin Activity And Nucleic Acids Encoding Same
    Publication number: 20090035820
    Abstract: The present invention relates to microbial trypsin variants having chymotrypsin-like activity, comprising: (a) a one or more substitutions corresponding to positions 144, S193A, 198, 201, 218, 223, 227, 228, 229, 230, and 231 of amino acids 25 to 248 of SEQ ID NO: 2, (b) one or more deletions corresponding to positions 192, 197, and 226 of amino acids 25 to 248 of SEQ ID NO: 2; and (c) an insertion between positions corresponding to positions 224 and 225 of amino acids 25 to 248 of SEQ ID NO: 2. The present invention further relates to nucleotide sequences encoding microbial trypsin variants having chymotrypsin-like activity; nucleic acid constructs, expression vectors, and recombinant host cells comprising such nucleotide sequences; and methods of producing microbial trypsin variants having chymotrypsin-like activity or a precursor thereof.
    Type: Application
    Filed: January 30, 2008
    Publication date: February 5, 2009
    Applicant: Novozymes, Inc.
    Inventors: Alan Klotz, Kimberly M. Brown, Elizabeth J. Zaretsky
  • Microbial trypsin mutants having chymotrypsin activity and nucleic acids encoding same
    Patent number: 7364892
    Abstract: The present invention relates to microbial trypsin variants having chymotrypsin-like activity, comprising: (a) a one or more substitutions corresponding to positions 144, 193, 198, 201, 218, 223, 227, 228, 229, 230, and 231 of amino acids 25 to 248 of SEQ ID NO: 2, (b) one or more deletions corresponding to positions 192, 197, and 226 of amino acids 25 to 248 of SEQ ID NO: 2; and (c) an insertion between positions corresponding to positions 224 and 225 of amino acids 25 to 248 of SEQ ID NO: 2. The present invention further relates to nucleotide sequences encoding microbial trypsin variants having chymotrypsin-like activity; nucleic acid constructs, expression vectors, and recombinant host cells comprising such nucleotide sequences; and methods of producing microbial trypsin variants having chymotrypsin-like activity or a precursor thereof.
    Type: Grant
    Filed: September 24, 2003
    Date of Patent: April 29, 2008
    Assignee: Novozymes, Inc.
    Inventors: Alan Klotz, Kimberly M. Brown, Elizabeth J. Zaretsky
  • Polypeptides having xyloglucanase activity and nucleic acids encoding same
    Patent number: 7172891
    Abstract: The present invention relates to isolated polypeptides having Family 74 xyloglucanase activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: December 6, 2005
    Date of Patent: February 6, 2007
    Assignee: Novozymes, Inc.
    Inventors: Michael W. Rey, Elizabeth J. Zaretsky, Jeffrey A. Haas
  • Polypeptides having xyloglucanase activity and nucleic acids encoding same
    Patent number: 7033811
    Abstract: The present invention relates to isolated polypeptides having Family 74 xyloglucanase activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: April 18, 2003
    Date of Patent: April 25, 2006
    Assignee: Novozymes, Inc.
    Inventors: Michael W. Rey, Elizabeth J. Zaretsky, Jeffrey A. Haas
  • Polypeptides having xyloglucanase activity and nucleic acids encoding same
    Publication number: 20040067569
    Abstract: The present invention relates to isolated polypeptides having Family 74 xyloglucanase activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: April 18, 2003
    Publication date: April 8, 2004
    Applicant: Novozymes Biotech, Inc.
    Inventors: Michael W. Rey, Elizabeth J. Zaretsky, Jeffrey A. Haas