Abstract: Provided herein are methods for preventing and/or reducing the severity of drug induced ototoxicity. Provided herein are methods for recovery from hearing loss due to drug-induced ototoxicity.

Abstract: Disclosed herein are otic formulations and compositions comprising growth factors. These otic formulations and compositions allow for the delivery of the growth factor to the outer, middle, and/or inner ear for the treatment of otic diseases and disorders.

Abstract: A multi layered wound dressing which comprises an adhesive layer, an absorbent layer overlying said adhesive layer on the surface furthest from the wound, and a moisture transmitting cover layer overlying the absorbent layer, the dressing having a total thickness of less than 1.5 mm.

Abstract: Methods of enhancing the photostabilizing of silver in medical materials are described. More particularly, the methods increase the photostabilization of silver in certain materials comprising hydrophilic, amphoteric and anionic polymers by subjecting the polymers to solutions containing an organic solvent and silver, during or after which one or more agents are added which facilitate the photostablization of the material.

Abstract: An iodine preparation composition suitable for use on wounds comprising an iodide source, an oxidant and a buffer characterized in that the iodide is held separately from the oxidant until the point of use, and that the buffer is capable of maintaining the pH of the composition at between pH 45 and pH 6 so that iodine is generated at a physiologically acceptable dose rate.

Abstract: A pharmaceutical foam formulation in a dosage form which comprises an active ingredient selected from the group consisting of minoxidil, minoxidil sulphate, other soluble minoxidil salts, and mixtures thereof. An embodiment also includes a surfactant, water, and optional further excipients. In an embodiment, the formulation is adapted to form a foam when administered by spraying.

Abstract: A multi layered wound dressing which comprises an adhesive layer, an absorbent layer overlying said adhesive layer on the surface furthest from the wound, and a moisture transmitting cover layer overlying the absorbent layer, the dressing having a total thickness of less than 1.5 mm.

Abstract: A multi layered wound dressing which comprises an adhesive layer, an absorbent layer overlying said adhesive layer on the surface furthest from the wound, and a moisture transmitting cover layer overlying the absorbent layer, the dressing having a total thickness of less than 1.5 mm.

Abstract: Methods of enhancing the photostabilizing of silver in medical materials are described. More particularly, the methods increase the photostabilization of silver in certain materials comprising hydrophilic, amphoteric and anionic polymers by subjecting the polymers to solutions containing an organic solvent and silver, during or after which one or more agents are added which facilitate the photostablization of the material.

Abstract: Methods of enhancing the photostabilizing of silver in medical materials are described. More particularly, the methods increase the photostabilization of silver in certain materials comprising hydrophilic, amphoteric and anionic polymers by subjecting the polymers to solutions containing an organic solvent and silver, during or after which one or more agents are added which facilitate the photostablization of the material.

Abstract: A multi layered wound dressing comprising: (a) an adsorbent layer having high absorbency but low lateral wicking rate, and (b) a transmission layer having a high moisture vapor transmission rate overlying the side of said absorbent layer furthest from the wound.

Abstract: A wound dressing comprises a blend of at least two types of discrete fibers wherein one discrete fiber is of a modified cellulose gel-forming material and a second discrete fiber is of another type of gel-forming material such as an alginate.

Abstract: A barrier aerosol vessel containing a wound gel for the treatment ol wounds. Wound gels packaged in this way have many advantages. Firstly, because there is positive pressure in the container, the vessel can be made to be self-sealing. This aids maintenance of product sterility. Secondly, it is possible to uise an aerosol using only one hand which makes application of the gel to the wound particularly easy. In the case of sinus wounds, where there is undermining of the tissue beneath the wound site and beyond its surface periphery, it is possible to insert the nozzle through the sinus to fill the cavity with gel. Thirdly, since the propellent is not mixed with the gel, the physical and chemical properties of the gel are not aflected by being dispensed in this manner.

Abstract: Methods of enhancing the photostabilizing of silver in medical materials are described. More particularly, the methods increase the photostabilization of silver in certain materials comprising hydrophilic, amphoteric and anionic polymers by subjecting the polymers to solutions containing an organic solvent and silver, during or after which one or more agents are added which facilitate the photostablization of the material.

Abstract: A multi layered wound dressing which comprises an adhesive layer, an absorbent layer overlying said adhesive layer on the surface furthest from the wound, and a moisture transmitting cover layer overlying the absorbent layer, the dressing having a total thickness of less than 1.5 mm.

Abstract: A novel wound dressing includes a fibrous absorbent layer for absorbing wound exudate, an odor layer for absorbing odor and a barrier layer interposed the fibrous absorbent and barrier layers. Preferably the barrier layer is vacuum perforated and the fibrous absorbent layer is of highly absorbent fibres capable of absorbing 25 grams of exudate per gram of dressing.

Abstract: A water soluble film having a thickness of from 0.03 mm to 0.5 mm comprising a water soluble polymer and an active substance.

Abstract: The present invention relates to a multi-layered wound dressing particularly for use as a dressing on highly exudating wounds.