Patents by Inventor Elizabeth M. Horstman

Elizabeth M. Horstman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FXR (NR1H4) MODULATING COMPOUNDS
    Publication number: 20220204491
    Abstract: The present disclosure relates generally to compounds that bind to FXR and act as agonists of FXR. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.
    Type: Application
    Filed: November 24, 2021
    Publication date: June 30, 2022
    Inventors: Peter A. Blomgren, Kevin S. Currie, Morin Mae Frick, Elizabeth M. Horstman, Joshua A. Kaplan, Jeffrey E. Kropf, William J. Watkins
  • FXR (NR1H4) modulating compounds
    Patent number: 11225473
    Abstract: The present disclosure relates generally to compounds that bind to FXR and act as agonists of FXR. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.
    Type: Grant
    Filed: January 13, 2020
    Date of Patent: January 18, 2022
    Assignee: Gilead Sciences, Inc.
    Inventors: Peter A. Blomgren, Kevin S. Currie, Morin Mae Frick, Elizabeth M. Horstman, Joshua A. Kaplan, Jeffrey E. Kropf, William J. Watkins
  • FXR (NR1H4) MODULATING COMPOUNDS
    Publication number: 20200255418
    Abstract: The present disclosure relates generally to compounds that bind to FXR and act as agonists of FXR. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.
    Type: Application
    Filed: January 13, 2020
    Publication date: August 13, 2020
    Inventors: Peter A. Blomgren, Kevin S. Currie, Morin Mae Frick, Elizabeth M. Horstman, Joshua A. Kaplan, Jeffrey E. Kropf, William J. Watkins
  • DESIGN AND COMPOSITION OF CELL-STABILIZED PHARMACEUTICAL FORMULATIONS
    Publication number: 20190262453
    Abstract: Provided herein are physiologically insoluble insoluble forms of drugs. In particular, provided herein are physiologically insoluble insoluble salts of drugs (e.g., basic drugs) and their use in treatment of disease.
    Type: Application
    Filed: October 24, 2017
    Publication date: August 29, 2019
    Inventors: Gustavo Rosania, Paul J.A. Kenis, Tehetina Woldemichael, Mikhail M. Murashov, Phillip Rzeczycki, Rahul K. Keswani, Elizabeth M. Horstman