Patents by Inventor Elizabeth M. Murphy Topp

Elizabeth M. Murphy Topp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified glucagon molecules
    Patent number: 11472857
    Abstract: The invention generally relates to modified glucagon molecules. In certain embodiments, the invention provides a glucagon molecule that includes one or more modified amino acids to result in the glucagon molecule being soluble at a substantially neutral pH and resistant to fibrillation. Modifications may include, for example, phosphorylation or sulfation.
    Type: Grant
    Filed: February 17, 2021
    Date of Patent: October 18, 2022
    Assignee: Purdue Research Foundation
    Inventors: Elizabeth M. Murphy Topp, Hamed Tabatabaei Ghomi, Markus Lill, Shenbaga Moorthy Balakrishnan
  • MODIFIED GLUCAGON MOLECULES
    Publication number: 20210300982
    Abstract: The invention generally relates to modified glucagon molecules. In certain embodiments, the invention provides a glucagon molecule that includes one or more modified amino acids to result in the glucagon molecule being soluble at a substantially neutral pH and resistant to fibrillation. Modifications may include, for example, phosphorylation or sulfation.
    Type: Application
    Filed: February 17, 2021
    Publication date: September 30, 2021
    Inventors: Elizabeth M. Murphy Topp, Hamed Tabatabaei Ghomi, Markus Lill, Shenbaga Moorthy Balakrishnan
  • Modified glucagon molecules
    Patent number: 10954283
    Abstract: The invention generally relates to modified glucagon molecules. In certain embodiments, the invention provides a glucagon molecule that includes one or more modified amino acids to result in the glucagon molecule being soluble at a substantially neutral pH and resistant to fibrillation. Modifications may include, for example, phosphorylation or sulfation.
    Type: Grant
    Filed: February 19, 2019
    Date of Patent: March 23, 2021
    Assignee: Purdue Research Foundation
    Inventors: Elizabeth M. Murphy Topp, Hamed Tabatabaei Ghomi, Markus Lill, Shenbaga Moorthy Balakrishnan
  • MODIFIED GLUCAGON MOLECULES
    Publication number: 20190202884
    Abstract: The invention generally relates to modified glucagon molecules. In certain embodiments, the invention provides a glucagon molecule that includes one or more modified amino acids to result in the glucagon molecule being soluble at a substantially neutral pH and resistant to fibrillation.
    Type: Application
    Filed: February 19, 2019
    Publication date: July 4, 2019
    Inventors: Elizabeth M. Murphy Topp, Hamed Tabatabaei Ghomi, Markus Lill, Shenbaga Moorthy Balakrishnan
  • Modified glucagon molecules
    Patent number: 10308701
    Abstract: The invention generally relates to modified glucagon molecules. In certain embodiments, the invention provides a glucagon molecule that includes one or more modified amino acids, e.g., phosphorylation and/or sulfation, to result in the glucagon molecule being soluble at a substantially neutral pH and resistant to fibrillation.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: June 4, 2019
    Assignee: Purdue Research Foundation
    Inventors: Elizabeth M. Murphy Topp, Hamed Tabatabaei Ghomi, Markus Lill, Shenbaga Moorthy Balakrishnan
  • MODIFIED GLUCAGON MOLECULES
    Publication number: 20180298076
    Abstract: The invention generally relates to modified glucagon molecules. In certain embodiments, the invention provides a glucagon molecule that includes one or more modified amino acids to result in the glucagon molecule being soluble at a substantially neutral pH and resistant to fibrillation.
    Type: Application
    Filed: July 22, 2016
    Publication date: October 18, 2018
    Inventors: Elizabeth M. Murphy Topp, Hamed Tabatabaei Ghomi, Markus Lill, Shenbaga Moorthy Balakrishnan