Abstract: Compounds of Formula I or a stereoisomer, tautomer, prodrug or pharmaceutically acceptable salt thereof are provided, which are useful for the treatment of hyperproliferative diseases.

Abstract: Noninvasive, dynamic, multi-wavelength, multi-pulse, multi-node photobiomodulation methods can be used to treat complex diseases (CDs), including, but not limited to cancer, diseases of the eye or brain, and arterial disease. Light is non-invasively provided to the skin of a body proximal a plurality of arteries. In various implementations, the optical signals applied to the body and/or the parameters of the regimen for applying the optical signals to the body are fractal in nature and/or are similar to or match fractals or characteristics of fractals in one or more biological signals, system, structures or processes.

Abstract: A device for non-invasive light delivery to a subject. The device includes a controller disposed in the housing, the controller being electrically connected to the power source; at least one waveform electronics assembly; a plurality of laser diodes disposed in the housing, the plurality of laser diodes being configured to operate in a super-pulsed regime, the controller being configured to operate the plurality of laser diodes with a Megahertz (MHz) modulation and peak power in milliwatts (mW), the plurality of laser diodes including at least one near-infrared laser diode, at least one mid-infrared laser diode, at least one far-infrared laser diode, and at least one visible-range laser diode; a plurality of optical fibers bundled into at least one fiber bundle, a distal end of the at least one fiber bundle being arranged and configured for delivering light from the plurality of optical fibers to the subject.

Abstract: A device for preventing leaks is disclosed herein. The device for preventing leaks includes a cylindrical body that may have a top end and a bottom end, a spring being biased within a hollow portion of the cylindrical body, a plurality of ball bearings located on an inner lower portion of the cylindrical body, a plurality of O-rings being removably located within the hollow portion of the cylindrical body, a sleeve being movably coupled to the cylindrical body, and wherein the device may be configured to prevent leakage from a pressurized valve.

Abstract: A data storage system, device, and method are provided for replicating data between different data storage systems or appliances. More specifically, the present invention affords communications between heterogeneous data storage systems that potential employ different communication protocols. A bridging communication protocol is utilized by one or both storage systems in order to accommodate different communication protocols. Alternatively, a storage appliance connecting the data storage systems may employ the bridging communication protocol.

Abstract: A data storage system, device, and method are provided for replicating data between different data storage systems or appliances. More specifically, the present invention allows an initiating data storage device to pull data from a target data storage device. Thus, the storage device that is supplying the data can act as a target and does not require the additional software inherent in being an initiator.