Abstract: A method for hierarchical clustering includes receiving a large set of data, training an algorithm to find patterns in the received data that most accurately predict the outcomes, and generating a multi-output model to maximize the cluster quality of a set of features. The data include at least two binary drivers and one binary need, the drivers predict the value of the need, and the data include at least two outcomes.

Abstract: A method of forming an implantable biomaterial comprising the steps of providing a polyether-diisocyanate prepolymer, reacting the prepolymer with one or more chain extender molecules typically including benzene 1,4-diol to form a mouldable polymer selected from a polyurethane or polyurethane-urea polymer or a polyurethane-urea block copolymer; placing the mouldable polymer into an implantable biomaterial shaped mould, and shaping and curing the mouldable polymer in the implantable biomaterial shaped mould to form the implantable biomaterial. An implantable biomaterial such as a heart valve leaflet is also disclosed.

Abstract: A toe bone implant for correction of toe bone deformities is provided. The toe bone implant includes a first portion having a socket portion. The toe bone implant also includes a second portion having a ball portion operatively connected to the socket portion. The toe bone implant is implanted in a joint such that the ball portion is configured to rotate a predetermined amount respective to the socket portion.

Abstract: In some embodiments, a surgical method includes creating an incision in a patient, exposing a multi-component prosthesis implanted in a patient, disassembling at least one component of the multi-component prosthesis, and coupling a first revision implant component to a first component of the multi-component prosthesis. The revision implant component has a body including at least one of a projection or an opening that is complementary to a feature of the first component of the multi-component prosthesis for coupling the revision implant component to the first component of the multi-component prosthesis.

Abstract: A toe bone implant for correction of toe bone deformities is provided. The toe bone implant includes a first portion having a socket portion. The toe bone implant also includes a second portion having a ball portion operatively connected to the socket portion. The toe bone implant is implanted in a joint such that the ball portion is configured to rotate a predetermined amount respective to the socket portion.

Abstract: A toe bone implant for correction of toe bone deformities is provided. The toe bone implant includes a first portion having a socket portion. The toe bone implant also includes a second portion having a ball portion operatively connected to the socket portion. The toe bone implant is implanted in a joint such that the ball portion is configured to rotate a predetermined amount respective to the socket portion.

Abstract: A toe bone implant for correction of toe bone deformities is provided. The toe bone implant includes a first portion having a socket portion. The toe bone implant also includes a second portion having a ball portion operatively connected to the socket portion. The toe bone implant is implanted in a joint such that the ball portion is configured to rotate a predetermined amount respective to the socket portion.

Abstract: A toe bone implant for correction of toe bone deformities is provided. The toe bone implant includes a first portion having a socket portion. The toe bone implant also includes a second portion having a ball portion operatively connected to the socket portion. The toe bone implant is implanted in a joint such that the ball portion is configured to rotate a predetermined amount respective to the socket portion.

Abstract: In some embodiments, a surgical method includes creating an incision in a patient, exposing a multi-component prosthesis implanted in a patient, disassembling at least one component of the multi-component prosthesis, and coupling a first revision implant component to a first component of the multi-component prosthesis. The revision implant component has a body including at least one of a projection or an opening that is complementary to a feature of the first component of the multi-component prosthesis for coupling the revision implant component to the first component of the multi-component prosthesis.

Abstract: A toe bone implant for correction of toe bone deformities is provided. The toe bone implant includes a first portion having a socket portion. The toe bone implant also includes a second portion having a ball portion operatively connected to the socket portion. The toe bone implant is implanted in a joint such that the ball portion is configured to rotate a predetermined amount respective to the socket portion.