Patents by Inventor Elizabeth Stanley

Elizabeth Stanley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240124861
    Abstract: Compositions and methods are provided for modulating growth of a genetically modified bacterial cell present in a human organ, for modulating growth of a genetically modified bacterial cell in an organ (e.g., gut), for displacing at least a portion of a population of bacterial cells in an organ, and for facilitating gut colonization by a genetically modified bacterial cell. Also provided are genetically modified bacterial cells, e.g., cells that include a heterologous carbohydrate-utilization gene or gene set that provides for the ability to utilize as a carbon source a rare carbohydrate of interest that is utilized as a carbon source by less than 50% of bacterial cells present in a human microbiome.
    Type: Application
    Filed: December 20, 2023
    Publication date: April 18, 2024
    Inventors: Justin L. Sonnenburg, Weston R. Whitaker, Elizabeth Stanley, William C. DeLoache
  • Publication number: 20240076641
    Abstract: Compositions and methods are provided for modulating growth of a genetically modified bacterial cell present in a human organ, for modulating growth of a genetically modified bacterial cell in an organ (e.g., gut), for displacing at least a portion of a population of bacterial cells in an organ, and for facilitating gut colonization by a genetically modified bacterial cell. Also provided are genetically modified bacterial cells, e.g., cells that include a heterologous carbohydrate-utilization gene or gene set that provides for the ability to utilize as a carbon source a rare carbohydrate of interest that is utilized as a carbon source by less than 50% of bacterial cells present in a human microbiome.
    Type: Application
    Filed: November 3, 2023
    Publication date: March 7, 2024
    Inventors: Justin L. Sonnenburg, Weston R. Whitaker, Elizabeth Stanley, William C. DeLoache
  • Publication number: 20240016858
    Abstract: Provided are nucleic acids that include a promoter, where the promoter is operable in a Bacteroides cell and is operably linked to a heterologous nucleotide sequence of interest. Also provided are nucleic acids that include a promoter (operable in a prokaryotic cell such as a Bacteroides cell) operably linked to a sequence encoding a synthetic ribosomal binding site (RBS). Also provided are fusion proteins (and nucleic acids encoding them) in which a secreted Bacteroides polypeptide is fused to a heterologous polypeptide of interest. Also provided are prokaryotic cells (e.g., E. coli, a Bacteroides cell, and the like) that include one more nucleic acids such as those described above. Also provided are methods of expression in a prokaryotic cell, methods of detectably labeling a Bacteroides cell in an animal's gut, and methods of delivering a protein to an individual's gut.
    Type: Application
    Filed: August 10, 2023
    Publication date: January 18, 2024
    Inventors: Justin L. Sonnenburg, Weston R. Whitaker, Elizabeth Stanley
  • Patent number: 11766461
    Abstract: Provided are nucleic acids that include a promoter, where the promoter is operable in a Bacteroides cell and is operably linked to a heterologous nucleotide sequence of interest. Also provided are nucleic acids that include a promoter (operable in a prokaryotic cell such as a Bacteroides cell) operably linked to a sequence encoding a synthetic ribosomal binding site (RBS). Also provided are fusion proteins (and nucleic acids encoding them) in which a secreted Bacteroides polypeptide is fused to a heterologous polypeptide of interest. Also provided are prokaryotic cells (e.g., E. coli, a Bacteroides cell, and the like) that include one more nucleic acids such as those described above. Also provided are methods of expression in a prokaryotic cell, methods of detectably labeling a Bacteroides cell in an animal's gut, and methods of delivering a protein to an individual's gut.
    Type: Grant
    Filed: April 18, 2017
    Date of Patent: September 26, 2023
    Assignee: The Board of Trustees of the Stanford Junior
    Inventors: Justin L. Sonnenburg, Weston R. Whitaker, Elizabeth Stanley
  • Patent number: 11566238
    Abstract: Compositions and methods are provided for modulating growth of a genetically modified bacterial cell present in a human organ, for modulating growth of a genetically modified bacterial cell in an organ (e.g., gut), for displacing at least a portion of a population of bacterial cells in an organ, and for facilitating gut colonization by a genetically modified bacterial cell. Also provided are genetically modified bacterial cells, e.g., cells that include a heterologous carbohydrate-utilization gene or gene set that provides for the ability to utilize as a carbon source a rare carbohydrate of interest that is utilized as a carbon source by less than 50% of bacterial cells present in a human microbiome.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: January 31, 2023
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Novome Biotechnologies, Inc.
    Inventors: Justin L. Sonnenburg, Weston R. Whitaker, Elizabeth Stanley, William C. DeLoache
  • Publication number: 20220177866
    Abstract: Compositions and methods are provided for modulating growth of a genetically modified bacterial cell present in a human organ, for modulating growth of a genetically modified bacterial cell in an organ (e.g., gut), for displacing at least a portion of a population of bacterial cells in an organ, and for facilitating gut colonization by a genetically modified bacterial cell. Also provided are genetically modified bacterial cells, e.g., cells that include a heterologous carbohydrate-utilization gene or gene set that provides for the ability to utilize as a carbon source a rare carbohydrate of interest that is utilized as a carbon source by less than 50% of bacterial cells present in a human microbiome.
    Type: Application
    Filed: February 18, 2022
    Publication date: June 9, 2022
    Inventors: Justin L. Sonnenburg, Weston R. Whitaker, Elizabeth Stanley, William C. DeLoache
  • Publication number: 20220160791
    Abstract: Provided are nucleic acids that include a promoter, where the promoter is operable in a Bacteroides cell and is operably linked to a heterologous nucleotide sequence of interest. Also provided are nucleic acids that include a promoter (operable in a prokaryotic cell such as a Bacteroides cell) operably linked to a sequence encoding a synthetic ribosomal binding site (RBS). Also provided are fusion proteins (and nucleic acids encoding them) in which a secreted Bacteroides polypeptide is fused to a heterologous polypeptide of interest. Also provided are prokaryotic cells (e.g., E. coli, a Bacteroides cell, and the like) that include one more nucleic acids such as those described above. Also provided are methods of expression in a prokaryotic cell, methods of detectably labeling a Bacteroides cell in an animal's gut, and methods of delivering a protein to an individual's gut.
    Type: Application
    Filed: April 18, 2017
    Publication date: May 26, 2022
    Inventors: Justin L. Sonnenburg, Weston R. Whitaker, Elizabeth Stanley
  • Patent number: 11254918
    Abstract: Compositions and methods are provided for modulating growth of a genetically modified bacterial cell present in a human organ, for modulating growth of a genetically modified bacterial cell in an organ (e.g., gut), for displacing at least a portion of a population of bacterial cells in an organ, and for facilitating gut colonization by a genetically modified bacterial cell. Also provided are genetically modified bacterial cells, e.g., cells that include a heterologous carbohydrate-utilization gene or gene set that provides for the ability to utilize as a carbon source a rare carbohydrate of interest that is utilized as a carbon source by less than 50% of bacterial cells present in a human microbiome.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: February 22, 2022
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Novome Biotechnolooies, Inc.
    Inventors: Justin L. Sonnenburg, Weston R. Whitaker, Elizabeth Stanley, William C. DeLoache
  • Patent number: 11175725
    Abstract: A method, computer system, and a computer program product for power-efficient location tracking is provided. The present invention may include, storing, by a first device, a first set of location data associated with a first segment mapping of a route, wherein the stored first set of location data is collected according to a group processing task. The present invention may include, receiving, from at least one second device, at least one second set of location data associated with at least one second segment mapping of the route, wherein the received at least one second set of location data is collected according to the group processing task. The present invention may include, mapping, based on combining the first set of collected location data and the received at least one second set of location data, a complete route including the first segment mapping and the at least one second segment mapping.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: November 16, 2021
    Assignee: International Business Machines Corporation
    Inventors: Katherine Elizabeth Stanley, James Russell, Sophie D. Green, Stephen R. F. Head
  • Publication number: 20210304341
    Abstract: In an approach, a processor provides multiple defined categories of sensitive information. For each post associated with an entity, a processor extracts one or more information portions. A processor determines one or more categories to which each of the one or more information portions is relevant. A processor analyzes a category's respective information portions to combine the respective information portions determined to be relevant to the category to determine whether the combination of the respective information portions discloses sensitive information.
    Type: Application
    Filed: March 26, 2020
    Publication date: September 30, 2021
    Inventors: Sophie D. Green, Robert William John Parker, Stephen R.F. Head, Katherine Elizabeth Stanley
  • Publication number: 20210054356
    Abstract: Compositions and methods are provided for modulating growth of a genetically modified bacterial cell present in a human organ, for modulating growth of a genetically modified bacterial cell in an organ (e.g., gut), for displacing at least a portion of a population of bacterial cells in an organ, and for facilitating gut colonization by a genetically modified bacterial cell. Also provided are genetically modified bacterial cells, e.g., cells that include a heterologous carbohydrate-utilization gene or gene set that provides for the ability to utilize as a carbon source a rare carbohydrate of interest that is utilized as a carbon source by less than 50% of bacterial cells present in a human microbiome.
    Type: Application
    Filed: November 6, 2020
    Publication date: February 25, 2021
    Inventors: Justin L. Sonnenburg, Weston R. Whitaker, Elizabeth Stanley, William C. DeLoache
  • Publication number: 20200293103
    Abstract: A method, computer system, and a computer program product for power-efficient location tracking is provided. The present invention may include, storing, by a first device, a first set of location data associated with a first segment mapping of a route, wherein the stored first set of location data is collected according to a group processing task. The present invention may include, receiving, from at least one second device, at least one second set of location data associated with at least one second segment mapping of the route, wherein the received at least one second set of location data is collected according to the group processing task. The present invention may include, mapping, based on combining the first set of collected location data and the received at least one second set of location data, a complete route including the first segment mapping and the at least one second segment mapping.
    Type: Application
    Filed: March 15, 2019
    Publication date: September 17, 2020
    Inventors: Katherine Elizabeth Stanley, James Russell, Sophie D. Green, Stephen R. F. Head
  • Publication number: 20200085884
    Abstract: Compositions and methods are provided for modulating growth of a genetically modified bacterial cell present in a human organ, for modulating growth of a genetically modified bacterial cell in an organ (e.g., gut), for displacing at least a portion of a population of bacterial cells in an organ, and for facilitating gut colonization by a genetically modified bacterial cell. Also provided are genetically modified bacterial cells, e.g., cells that include a heterologous carbohydrate-utilization gene or gene set that provides for the ability to utilize as a carbon source a rare carbohydrate of interest that is utilized as a carbon source by less than 50% of bacterial cells present in a human microbiome.
    Type: Application
    Filed: December 14, 2017
    Publication date: March 19, 2020
    Inventors: Justin L. Sonnenburg, Weston R. Whitaker, Elizabeth Stanley, William C. DeLoache
  • Publication number: 20190055529
    Abstract: Compositions and methods are provided for modulating growth of a genetically modified bacterial cell present in a human organ, for modulating growth of a genetically modified bacterial cell in an organ (e.g., gut), for displacing at least a portion of a population of bacterial cells in an organ, and for facilitating gut colonization by a genetically modified bacterial cell. Also provided are genetically modified bacterial cells, e.g., cells that include a heterologous carbohydrate-utilization gene or gene set that provides for the ability to utilize as a carbon source a rare carbohydrate of interest that is utilized as a carbon source by less than 50% of bacterial cells present in a human microbiome.
    Type: Application
    Filed: July 27, 2018
    Publication date: February 21, 2019
    Inventors: Justin L. Sonnenburg, Weston R. Whitaker, Elizabeth Stanley, William C. DeLoache
  • Publication number: 20040200143
    Abstract: A plant collar support and containment system for the growing and supporting plants and preventing the onset of diseases and rotting by supporting a plant\.
    Type: Application
    Filed: February 24, 2004
    Publication date: October 14, 2004
    Inventor: Elizabeth Stanley