Patents by Inventor Elizabeth Strychalski

Elizabeth Strychalski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gradient elution isotachophoretic apparatus for separating, purifying, concentrating, quantifying, and/or extracting charged analytes and methods thereof
    Patent number: 10067088
    Abstract: Gradient elution isotachophoretic apparatus, and systems for performing gradient elution isotachophoresis to separate, purify, concentrate, quantify, and/or extract charged analytes from a sample. The isotachophoretic apparatus include an electrophoretic assembly, a sampling assembly connected to the electrophoretic assembly, and/or a support structure connected to the electrophoretic assembly and/or to the sampling assembly. The system includes an isotachophoretic apparatus, and a controller communicatively coupled to the isotachophoretic apparatus. The controller includes a storage medium and a processor for executing computer readable and executable instructions.
    Type: Grant
    Filed: June 22, 2015
    Date of Patent: September 4, 2018
    Assignees: Applied Research Associates, Inc., The United States of America, as Represented by the Secretary of Commerce National Institute of Standards and Technology
    Inventors: Alyssa Henry, Christopher Konek, David Ross, Elizabeth Strychalski
  • Methods and apparatus for transplantation of nucleic acid molecules
    Patent number: 9834747
    Abstract: In exemplary implementations, transplantation of nucleic acids into cells occurs in microfluidic chambers. The nucleic acids may be large nucleic acid molecules with more than 100 kbp. In some cases, the microfluidic chambers have only one orifice that opens to a flow channel. In some cases, flow through a microfluidic chamber temporarily ceases due to closing one or more valves. Transplantation occurs during a period in which the contents of the chambers are shielded from shear forces. Diffusion, centrifugation, suction from a vacuum channel, or dead-end loading may be used to move cells or buffers into the chambers.
    Type: Grant
    Filed: July 31, 2014
    Date of Patent: December 5, 2017
    Assignee: Massachusetts Institute of Technology
    Inventors: Andreas Mershin, James Pelletier, Neil Gershenfeld, John Glass, Elizabeth Strychalski
  • GRADIENT ELUTION ISOTACHOPHORETIC APPARATUS FOR SEPARATING, PURIFYING, CONCENTRATING, QUANTIFYING, AND/OR EXTRACTING CHARGED ANALYTES AND METHODS THEREOF
    Publication number: 20160139078
    Abstract: Gradient elution isotachophoretic apparatus, and systems for performing gradient elution isotachophoresis to separate, purify, concentrate, quantify, and/or extract charged analytes from a sample. The isotachophoretic apparatus include an electrophoretic assembly, a sampling assembly connected to the electrophoretic assembly, and/or a support structure connected to the electrophoretic assembly and/or to the sampling assembly. The system includes an isotachophoretic apparatus, and a controller communicatively coupled to the isotachophoretic apparatus. The controller includes a storage medium and a processor for executing computer readable and executable instructions.
    Type: Application
    Filed: June 22, 2015
    Publication date: May 19, 2016
    Inventors: Alyssa Henry, Christopher Konek, David Ross, Elizabeth Strychalski
  • Methods and Apparatus for Transplantation of Nucleic Acid Molecules
    Publication number: 20150037890
    Abstract: In exemplary implementations, transplantation of nucleic acids into cells occurs in microfluidic chambers. The nucleic acids may be large nucleic acid molecules with more than 100 kbp. In some cases, the microfluidic chambers have only one orifice that opens to a flow channel. In some cases, flow through a microfluidic chamber temporarily ceases due to closing one or more valves. Transplantation occurs during a period in which the contents of the chambers are shielded from shear forces. Diffusion, centrifugation, suction from a vacuum channel, or dead-end loading may be used to move cells or buffers into the chambers.
    Type: Application
    Filed: July 31, 2014
    Publication date: February 5, 2015
    Applicant: Massacusetts Institute of Technology
    Inventors: Andreas Mershin, James Pelletier, Neil Gershenfeld, John Glass, Elizabeth Strychalski
  • Channel and method of forming channels
    Patent number: 8486348
    Abstract: A device is made by forming sacrificial fibers on a substrate mold. The fibers and mold are covered with a first material. The substrate mold is removed, and the covered fibers are then removed to form channels in the first material.
    Type: Grant
    Filed: October 28, 2010
    Date of Patent: July 16, 2013
    Assignee: Cornell University
    Inventors: Leon M. Bellan, Harold G. Craighead, Elizabeth A. Strychalski
  • CHANNEL AND METHOD OF FORMING CHANNELS
    Publication number: 20120107194
    Abstract: A device is made by forming sacrificial fibers on a substrate mold. The fibers and mold are covered with a first material. The substrate mold is removed, and the covered fibers are then removed to form channels in the first material.
    Type: Application
    Filed: October 28, 2010
    Publication date: May 3, 2012
    Applicant: Cornell University
    Inventors: Leon M. Bellan, Harold G. Craighead, Elizabeth A. Strychalski