Patents by Inventor Elizabeth Vera Ludmila Grgacic

Elizabeth Vera Ludmila Grgacic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Viral vectors expressing fusion of viral large envelope protein and protein of interest
    Patent number: 7678374
    Abstract: The present invention provides a virus-like particle (VLP) comprising i) a polypeptide comprising a polypeptide of interest (POI) and at least a particle-associating portion of a large envelope (L) polypeptide of an avian hepadnavirus or a functional derivative or homolog thereof, and ii) a small envelope (S) polypeptide of an avian hepadnavirus or a functional derivative or homolog thereof. By introducing one or more POIs into the L polypeptide, the POI is translocated along with L into a particle structure made up primarily of S polypeptide. The present invention furthermore provides methods for producing a recombinant virus-like particle.
    Type: Grant
    Filed: April 16, 2004
    Date of Patent: March 16, 2010
    Assignee: Hepgenics Pty Ltd
    Inventors: David Andrew Anderson, Elizabeth Vera Ludmila Grgacic