Patents by Inventor Elizabeth ZIEMKE

Elizabeth ZIEMKE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION WITH CHECKPOINT INHIBITORS TO TREAT CANCER
    Publication number: 20220202818
    Abstract: A combination comprising a compound of Formula (I) and/or Formula (Ia), or a pharmaceutically acceptable salt thereof, and at least one immune checkpoint modulator. Methods for the prevention and treatment of a cancer comprises administering to a subject in need thereof, a therapeutically effective amount of a combination, the combination comprising: a compound of Formula (I) and/or Formula (Ia), or a pharmaceutically acceptable salt thereof, and at least one immune checkpoint modulator.
    Type: Application
    Filed: April 18, 2020
    Publication date: June 30, 2022
    Inventors: Christopher E. Whitehead, Judith S. Leopold, Elizabeth Ziemke
  • SMALL MOLECULE DUAL INHIBITORS OF EGFR/PI3K AND USES THEREOF
    Publication number: 20200078360
    Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to anew class of small-molecules having a quinazoline structure which function as dual inhibitors EGFR and PI3K, and their use as therapeutics for the treatment of cancer (e.g., cancers associated with mutated KRAS and BRAF) (e.g., in combination with MAPK pathway inhibitors (e.g., BRAF inhibitors, MEK inhibitors, ERK inhibitors).
    Type: Application
    Filed: November 3, 2017
    Publication date: March 12, 2020
    Inventors: Christopher Emil WHITEHEAD, Elizabeth ZIEMKE, Judith SEBOLT-LEOPOLD