Patents by Inventor Elizaveta LESHCHINER

Elizaveta LESHCHINER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11382908
    Abstract: Disclosed herein are compounds for the treatment of inflammatory bowel disease. Additionally, provided herein are compositions and methods for using these compounds and compositions in the treatment of inflammatory bowel disease in a subject.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: July 12, 2022
    Assignees: The Broad Institute, Inc., The General Hospital Corporation, President and Fellows of Harvard College
    Inventors: Elizaveta Leshchiner, Zhifang Cao, Jason Rush, Michael Durney, Alykhan Shamji, Daniel Graham, Stuart L. Schreiber, Ramnik Xavier
  • Publication number: 20200268736
    Abstract: Disclosed herein are compounds for the treatment of inflammatory bowel disease. Additionally, provided herein are compositions and methods for using these compounds and compositions in the treatment of inflammatory bowel disease in a subject.
    Type: Application
    Filed: September 26, 2018
    Publication date: August 27, 2020
    Inventors: Elizaveta Leshchiner, Zhifang Cao, Jason Rush, Michael Durney, Alykhan Shamji, Daniel Graham, Stuart L. Schreiber, Ramnik Xavier
  • Patent number: 10087215
    Abstract: Provided herein are polypeptides containing stabilized therapeutic peptides related to KRAS guanidine exchange factor (SOS1). Also provided are compositions containing these polypeptides and methods of using such peptides in the treatment of cancer that includes administering to a subject one of the polypeptides. This disclosure relates to structurally stabilized therapeutic peptides related to KRAS guanidine exchange factor (SOS1), and methods of using such peptides in the treatment of cancer.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: October 2, 2018
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Elizaveta Leshchiner, Loren D. Walensky
  • Publication number: 20160046671
    Abstract: Provided herein are polypeptides containing stabilized therapeutic peptides related to KRAS guanidine exchange factor (SOS1). Also provided are compositions containing these polypeptides and methods of using such peptides in the treatment of cancer that includes administering to a subject one of the polypeptides. This disclosure relates to structurally stabilized therapeutic peptides related to KRAS guanidine exchange factor (SOS1), and methods of using such peptides in the treatment of cancer.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 18, 2016
    Inventors: Elizaveta LESHCHINER, Loren D. WALENSKY