Patents by Inventor Elizaveta SAVICHEVA

Elizaveta SAVICHEVA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12174197
    Abstract: Sulfonated 2(7)-aminoacridone and 1-aminopyrene dyes and their use as fluorescent tags, in particular for carbohydrate analysis The invention relates to fluorescent dyes with multiple negatively charged groups in their ionized form which are aminoacridone sulfonamides or 1-aminopyrenes having of one of the following general formulae A-D: Formula (A), Formula (B), Formula (C), Formula (D), wherein the ionizable groups X are typically selected from the following: SH, COOH, SO3H, OSO3H, OP(O)(OH)2, OP(O)(OH)Ra, P(O)(OH)2, P(O)(OH)Ra, where Ra?C1-C4alkyl or substituted C1-C4alkyl. The invention further relates to the use of these dyes as fluorescent tags, in particular for reducing sugars and glycans.
    Type: Grant
    Filed: January 21, 2019
    Date of Patent: December 24, 2024
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e. V.
    Inventors: Stefan W. Hell, Vladimir N. Belov, Matthias Bischoff, Dirk Meineke, Laura Thomas, Gyuzel Mitronova, Elizaveta Savicheva, Kirill Kolmakov, Marvin J. Boehm, Erdmann Rapp, René Hennig
  • Publication number: 20230040324
    Abstract: The invention relates to novel fluorescent dyes with multiple negatively charged groups in their ionized form which are 9-aminoacridines or 1-aminopyrene shaving of one of the following general formulae A-E: or salts or protonated forms thereof, wherein the ionizable groups are typically selected from the following: OH, SH, COOH, SO3H, OSO3H, SO2NHCN, P(O)(OH)2, P(O) (OH)2. The invention further relates to the use of these dyes as fluorescent tags, in particular for reducing sugars and glycans, and to carbohydrate-dye conjugates comprising these dyes as well as to methods for preparing the same.
    Type: Application
    Filed: December 6, 2019
    Publication date: February 9, 2023
    Inventors: Maksim A. FOMIN, Elizaveta SAVICHEVA, Jan SEIKOWSKI, Vladimir N. BELOV, Stefan W. HELL
  • Publication number: 20220107325
    Abstract: Sulfonated 2(7)-aminoacridone and 1-aminopyrene dyes and their use as fluorescent tags, in particular for carbohydrate analysis The invention relates to fluorescent dyes with multiple negatively charged groups in their ionized form which are aminoacridone sulfonamides or 1-aminopyrenes having of one of the following general formulae A-D: Formula (A), Formula (B), Formula (C), Formula (D), wherein the ionizable groups X are typically selected from the following: SH, COOH, SO3H, OSO3H, OP(O)(OH)2, OP(O)(OH)Ra, P(O)(OH)2, P(O)(OH)Ra, where Ra?C1-C4alkyl or substituted C1-C4alkyl. The invention further relates to the use of these dyes as fluorescent tags, in particular for reducing sugars and glycans.
    Type: Application
    Filed: January 21, 2019
    Publication date: April 7, 2022
    Inventors: Stefan W. HELL, Vladimir N. BELOV, Matthias BISCHOFF, Dirk MEINEKE, Laura THOMAS, Gyuzel MITRONOVA, Elizaveta SAVICHEVA, Kirill KOLMAKOV, Marvin J. BOEHM, Erdmann RAPP, René HENNIG
  • Publication number: 20220026434
    Abstract: The present invention relates to improved (simplified/easier, more robust and more reproducible) methods for identification of carbohydrates compositions, e.g. out of complex carbohydrate mixtures, as well as the determination of carbohydrate mixture composition patterns (e.g.: of glycosylation patterns) based on advanced internal standards to determine precise and highly reproducible migration and retention time indices using novel fluorescent dyes in combination with high performance separation technologies, like capillary (gel) electrophoresis (C(G)E) or (ultra)high performance liquid chromatography (U)HPLC with a highly sensitive detection like (laser induced) fluorescence detection.
    Type: Application
    Filed: January 21, 2019
    Publication date: January 27, 2022
    Inventors: Erdmann RAPP, René HENNIG, Udo REICHL, Stefan HELL, Vladimir BELOV, Matthias BISCHOFF, Dirk MEINEKE, Laura THOMAS, Kirill KOLMAKOV, Gyuzel MITRONOVA, Elizaveta SAVICHEVA