Patents by Inventor Elke Jager

Elke Jager has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolated nucleic acid molecules encoding cancer associated antigens, the antigens per se, and uses thereof
    Patent number: 6448073
    Abstract: The invention relates to isolated, cancer associated antigens, nucleic acid molecules, and various uses thereof.
    Type: Grant
    Filed: January 28, 2000
    Date of Patent: September 10, 2002
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Dirk Jager, Elizabeth Stockert, Matthew Scanlan, Ali Gure, Elke Jager, Alexander Knuth, Lloyd Old, Yao-tseng Chen
  • Renal cancer associated antigens and uses therefor
    Patent number: 6440663
    Abstract: Cancer associated antigens have been identified by autologous antibody screening of libraries of nucleic acids expressed in renal cancer cells using antisera from cancer patients. The invention relates to nucleic acids and encoded polypeptides which are cancer associated antigens expressed in patients afflicted with renal cancer. The invention provides, inter alia, isolated nucleic acid molecules, expression vectors containing those molecules and host cells transfected with those molecules. The invention also provides isolated proteins and peptides, antibodies to those proteins and peptides and cytotoxic T lymphocytes which recognize the proteins and peptides. Fragments of the foregoing including functional fragments and variants also are provided. Kits containing the foregoing molecules additionally are provided. The molecules provided by the invention can be used in the diagnosis, monitoring, research, or treatment of conditions characterized by the expression of one or more cancer associated antigens.
    Type: Grant
    Filed: October 5, 1998
    Date of Patent: August 27, 2002
    Assignees: Ludwig Institute for Cancer Research, The New York Hospital-Cornell Medical Center
    Inventors: Matthew J. Scanlan, Elisabeth Stockert, Yao-Tseng Chen, Lloyd J. Old, Elke Jager, Alex Knuth
  • Isolated nucleic acid molecule encoding cancer associated antigen, the antigen itself, and uses thereof
    Publication number: 20020111470
    Abstract: The invention relates to the isolation of a nucleic acid molecule which encodes a cancer associated antigen. Also a part of the invention is the antigen itself, and the uses of the nucleic acid molecule and the antigen, and peptides derived from it.
    Type: Application
    Filed: July 6, 2001
    Publication date: August 15, 2002
    Inventors: Yao-Tseng Chen, Ali Gure, Solam Tsang, Elisabeth Stockert, Elke Jager, Knuth Alexander, Lloyd J. Old
  • Truncated forms of NY-ESO-1 protein
    Publication number: 20020010321
    Abstract: The invention relates to antibodies which bind to the cancer associated antigen NY-ESO-1. Both polyclonal and monoclonal antibodies are part of the invention, as are chimeric forms of the antibodies, and binding portions of antibodies. Uses of these antibodies are described. Also described are truncated, recombinant forms of the cancer associated antigen.
    Type: Application
    Filed: December 29, 2000
    Publication date: January 24, 2002
    Inventors: Yao-tseng Chen, Matthew Scanlan, Ali O. Gure, Lloyd J. Old, Ozlem Tureci, Ugur Sahin, Michael Pfreundschuh, Elisabeth Stockert, Elke Jager, Knuth Alexander
  • Isolated nucleic acid molecule encoding cancer associated antigen, the antigen itself, and uses thereof
    Patent number: 6297364
    Abstract: The invention relates to the isolation of a nucleic acid molecule which encodes a cancer associated antigen. Also a part of the invention is the antigen itself, and the uses of the nucleic acid molecule and the antigen, and peptides derived from it.
    Type: Grant
    Filed: April 17, 1998
    Date of Patent: October 2, 2001
    Assignees: Ludwig Institute For Cancer Research, Cornell Research Foundation, Inc., Memorial Sloan-Kettering Cancer Center
    Inventors: Yao-Tseng Chen, Ali Gure, Solam Tsang, Elisabeth Stockert, Elke Jäger, Knuth Alexander, Lloyd J. Old
  • Isolated nucleic acid molecule encoding cancer associated antigen, the antigen itself, and uses thereof
    Patent number: 6274145
    Abstract: The invention relates to the isolation of a nucleic acid molecule which encodes a cancer associated antigen. Also a part of the invention is the antigen itself, and the uses of the nucleic acid molecule and the antigen, and peptides derived from it.
    Type: Grant
    Filed: September 15, 1997
    Date of Patent: August 14, 2001
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Yao-tseng Chen, Matthew Scanlan, Ali Guré, Lloyd J. Old, Elke Jäger, Knuth Alexander, Jan W. Drijfhout, Ozlem Tureci, Ugur Sahin, Michael Pfreundschuh
  • Antibodies which bind to NY-ESO-1 cancer associated proteins, and hybridomas which produce these antibodies
    Patent number: 6252052
    Abstract: The invention relates to antibodies which bind to the cancer associated antigen NY-ESO-1. Both polyclonal and monoclonal antibodies are part of the invention, as are chimeric forms of the antibodies, and binding portions of antibodies. Uses of these antibodies are described. Also described are truncated, recombinant forms of the cancer associated antigen.
    Type: Grant
    Filed: April 17, 1998
    Date of Patent: June 26, 2001
    Assignees: Cornell Research Foundation, Inc, Ludwig Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center
    Inventors: Elisabeth Stockert, Elke Jäger, Yao-tseng Chen, Matthew Scanlan, Knuth Alexander, Lloyd J. Old
  • Method for determining status of a cancerous condition by determining antibodies to NY-ESO-1 in a patient sample
    Patent number: 6251603
    Abstract: The invention relates to methods for determining tumor status by determining antibodies specific to NY-ESO-1 in patient samples. One can determine whether a cancerous condition is progressing, regressing, or remaining stable by determining antibodies against NY-ESO-1 in a patient sample, and comparing the value obtained to a prior value. When the tumor in question expresses NY-ESO-1, a change in this value is indicative of a change in status of the cancerous condition.
    Type: Grant
    Filed: July 23, 1999
    Date of Patent: June 26, 2001
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Elke Jäger, Elisabeth Stockert, Lloyd J. Old, Alexander Knuth
  • Compositions containing immunogenic molecules and granulocyte-macrophage colony stimulating factor, as an adjuvant
    Patent number: 6096313
    Abstract: Granulocyte-macrophage colony stimulating factor ("GM-CSF") has been found to act as an adjuvant when administered to subjects. Compositions of GM-CSF and immunogenic compositions are presented, as is the use of GM-CSF alone and in these compositions.
    Type: Grant
    Filed: February 9, 1996
    Date of Patent: August 1, 2000
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Elke Jager, Alexander Knuth