Patents by Inventor Ella Li

Ella Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Albumin binding antibodies and use thereof
    Patent number: 12479909
    Abstract: The present disclosure provides anti-albumin constructs each comprising an antialbumin single-domain antibody (sdAb) moiety. The anti-albumin constructs can further comprise a therapeutic agent, such as an antigen binding moiety or a cytokine. The present disclosure also provides methods of making and using the anti-albumin constructs.
    Type: Grant
    Filed: February 21, 2020
    Date of Patent: November 25, 2025
    Assignee: ANWITA BIOSCIENCES, INC.
    Inventors: Ziyang Zhong, Fan Ye, Matthew Siegel, Jianing Huang, Eric Liao, Ella Li
  • Cytokine-albumin binding moiety fusion proteins and uses thereof
    Patent number: 12215130
    Abstract: The present application provides fusion proteins that comprise a cytokine fused to an albumin binding moiety. The fusion proteins may further comprise an antigen binding moiety such as a therapeutic antibody. The present application also provides methods of making and using the fusion proteins. The present application also provides methods of treatment comprises administering a fusion protein comprising a cytokine fused to a half-life extending domain and a second agent.
    Type: Grant
    Filed: June 17, 2019
    Date of Patent: February 4, 2025
    Assignee: ANWITA BIOSCIENCES, INC.
    Inventors: Ziyang Zhong, Fan Ye, Matthew Siegel, Jianing Huang, Eric Liao, Ella Li
  • Interleukin-2 polypeptides and fusion proteins thereof, and their pharmaceutical compositions and therapeutic applications
    Patent number: 11897930
    Abstract: Provided herein are an interleukin-2 polypeptide and a fusion protein thereof. Also provided herein are their pharmaceutical compositions and methods of use for treating, preventing, or ameliorating one or more symptoms of a proliferative disease.
    Type: Grant
    Filed: April 27, 2021
    Date of Patent: February 13, 2024
    Assignee: Anwita Biosciences, Inc.
    Inventors: Fan Ye, Eric Liao, Ella Li, Matthew Siegel, Jianing Huang, Ziyang Zhong
  • ALBUMIN BINDING ANTIBODIES AND USE THEREOF
    Publication number: 20220195021
    Abstract: The present disclosure provides anti-albumin constructs each comprising an antialbumin single-domain antibody (sdAb) moiety. The anti-albumin constructs can further comprise a therapeutic agent, such as an antigen binding moiety or a cytokine. The present disclosure also provides methods of making and using the anti-albumin constructs.
    Type: Application
    Filed: February 21, 2020
    Publication date: June 23, 2022
    Inventors: Ziyang Zhong, Fan Ye, Matthew Siegel, Jianing Huang, Eric Liao, Ella Li
  • INTERLEUKIN-2 POLYPEPTIDES AND FUSION PROTEINS THEREOF, AND THEIR PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC APPLICATIONS
    Publication number: 20210340208
    Abstract: Provided herein are an interleukin-2 polypeptide and a fusion protein thereof. Also provided herein are their pharmaceutical compositions and methods of use for treating, preventing, or ameliorating one or more symptoms of a proliferative disease.
    Type: Application
    Filed: April 27, 2021
    Publication date: November 4, 2021
    Inventors: Fan Ye, Eric Liao, Ella Li, Matthew Siegel, Jianing Huang, Ziyang Zhong
  • CYTOKINE FUSION PROTEINS AND USES THEREOF
    Publication number: 20210230242
    Abstract: The present application provides fusion proteins that comprise a cytokine fused to an albumin binding moiety. The fusion proteins may further comprise an antigen binding moiety such as a therapeutic antibody. The present application also provides methods of making and using the fusion proteins. The present application also provides methods of treatment comprises administering a fusion protein comprising a cytokine fused to a half-life extending domain and a second agent.
    Type: Application
    Filed: June 17, 2019
    Publication date: July 29, 2021
    Inventors: Ziyang Zhong, Fan Ye, Matthew Siegel, Jianing Huang, Eric Liao, Ella Li