Abstract: The present invention relates to compositions and methods to improve the microenvironments in and around the wound in an effort to enhance healing. Specifically, the present invention comprises application of tissue and cells culture nutrient media, such as minimum essential media, supplemented with insulin and/or with substances exhibiting insulin-like activity, such as cinnamon or cinnamon extracts including but not limited to MHCP. The media is applied to the wound to stimulate the viable cells in the wound bed and the adjacent cells in the periphery of the wound to proliferate and grow into the wound in order to achieve wound closure.

Abstract: The present invention realtes to compositions and methods to improve the microenvironments in and around the wound in an effort to enhance healing. Specifically, the present invention comprises application of tissue and cells culture nutrient media, such as minimum essential media, supplemented with insulin and/or with substances exhibiting insulin-like activity, such as cinnamon or cinnamon extracts including but not limited to MHCP. The media is applied to the wound to stimulate the viable cells in the wound bed and the adjacent cells in the periphery of the wound to proliferate and grow into the wound in order to achieve wound closure.

Abstract: The present invention is a method of dermal abrasion, that includes exposing a source of sterile liquid to a flow of pressurized gas, thereby causing a pumped supply thereof into a fluid delivery head (200); supplying the pressurized gas to the fluid delivery head; combining the gas, and liquid (204) supplied to the delivery head; this fluid delivery head having a fluid outlet (206) with a predetermined internal diameter (210), so as to provide a gas-liquid outflow in the form of a sterile liquid mist jet suspended in a high velocity gas stream; and exposing to the mist jet, at a preselected distance from the fluid outlet, a portion of the skin surface (224) sought to be abraded, thereby separating therefrom at least a portion of the epidermis (225), and removing therefrom the resulting tissue debris.

Abstract: The present invention relates to the treatment of keloid and hypertrophic scars by covering the scar with a gas-or gel-filled cushion made of smooth or textured silicone sheeting. It relates particularly to a cushion in the form of a hollow bag filled with completely dry air, inert gel or an inert gas. The invention also relates to a silicone sheeting cushion enclosing silicone beads, polymeric pieces or bodies made of polyfluoroethylene sheeting or a related polymer which produces a negative static charge or, preferably, a silicone sponge or hydrophobic gel, most preferably silicone gel.

Abstract: The present invention relates to compositions and methods for enhancing the success of autologous fat grafting in a patient. The compositions according to the present invention are useful for enhancing autologous fat grafting by improving the survival rate of lipocytes which are injected into a patient as part of a fat grafting procedure. These compositions comprise a fat grafting effective amount of autologous lipocytes in combination with a lipocyte growth effective amount of a non-steroidal anabolic hormone selected from insulin, triiodothyronine/thyroxine (T.sub.3 or T.sub.4), mixtures thereof, and optionally, growth hormone, most preferably a mixture of all three hormones because of the favorable effect these three hormones exhibit in combination to promote autologous fat grafting, the hormones being further combined with a lipocyte growth effective amount of a nutrient medium, preferably a serum free nutrient medium as at least a minimum essential medium.

Abstract: The present invention relates to wound treatment formulations and methods for treating wounds utilizing these formulations. The formulations according to the present invention are useful for treating wounds by accelerating wound healing. These formulations generally comprise an effective amount of a non-steroidal anabolic hormone such as insulin, growth hormone, triiodothyronine, thyroxine or mixtures thereof, in combination with a cellular nutrient medium, preferably MCDB 153.

Abstract: The present invention relates to formulations and methods for treating wounds utilizing these formulations. The formulations according to the present invention are useful for treating wounds by accelerating wound healing. These formulations comprise an effective amount of a serum free cellular nutrient medium in combination with an effective amount of at least one cellular growth stimulating compound, e.g. a natural anabolic hormone or transforming growth factor.