Patents by Inventor Ella Y. Fung

Ella Y. Fung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monocyclic functional dyes for contrast enhancement in optical imaging
    Patent number: 5723104
    Abstract: This invention provides functional dyes of the general formula: ##STR1## wherein R.sup.1, R.sup.2, and R.sup.5 may be the same or different and are selected from the group consisting of hydrogen, C.sub.1 -C.sub.10 alkyl, C.sub.1 -C.sub.10 alkoxyl, hydroxyl, C.sub.1 -C.sub.10 hydroxyalkyl, C.sub.1 -C.sub.10 alkoxyalkyl, C.sub.1 -C.sub.10 aryl, carboxyl, C.sub.1 -C.sub.10 carboxylalkyl, halogen, nitro, C.sub.1 -C.sub.10 alkoxycarbonyl, mercapto, C.sub.1 -C.sub.10 mercaptoalkyl, C.sub.1 -C.sub.10 alkylthio, sulfonate, and --(CH.sub.2).sub.m --N(R.sup.6)(R.sup.7) wherein R.sup.6 and R.sup.7 are independently hydrogen or C.sub.1 -C.sub.10 alkyl, C.sub.1 -C.sub.10 acyl, and R.sup.6 and R.sup.7 are capable of forming 5, 6, or 7 membered rings which may optionally be substituted with --O--, --NR.sup.8, or --S--; R.sup.3 and R.sup.4 may be the same or different and are selected from the group consisting of C.sub.1 -C.sub.10 alkyl, C.sub.1 -C.sub.10 hydroxyalkyl, C.sub.1 -C.sub.10 alkoxyalkyl, C.sub.1 -C.sub.
    Type: Grant
    Filed: May 13, 1996
    Date of Patent: March 3, 1998
    Inventors: Ella Y. Fung, Raghavan Rajagopalan
  • Tricyclic functional dyes for contrast enhancement in optical imaging
    Patent number: 5709845
    Abstract: This invention provides functional dyes of the general formula: ##STR1## wherein R.sup.1, R.sup.2, and R.sup.5 may be the same or different and are selected from the group consisting of hydrogen, C.sub.1 -C.sub.10 alkyl, C.sub.1 -C.sub.10 alkoxyl, hydroxyl, C.sub.1 -C.sub.10 hydroxyalkyl, C.sub.1 -C.sub.10 alkoxyalkyl, C.sub.1 -C.sub.10 aryl, carboxyl, C.sub.1 -C.sub.10 carboxylalkyl, halogen, nitro, C.sub.1 -C.sub.10 alkoxycarbonyl, mercapto, C.sub.1 -C.sub.10 mercaptoalkyl, C.sub.1 -C.sub.10 alkylthio, sulfonate, and --(CH.sub.2).sub.m --N(R.sup.6)(R.sup.7) wherein R.sup.6 and R.sup.7 are independently hydrogen or C.sub.1 -C.sub.10 alkyl, C.sub.1 -C.sub.10 acyl, and R.sup.6 and R.sup.7 are capable of forming 5, 6, or 7 membered rings which may optionally be substituted with --O--, --NR.sup.8, or --S--; R.sup.3 and R.sup.4 may be the same or different and are selected from the group consisting of C.sub.1 -C.sub.10 alkyl, C.sub.1 -C.sub.10 hydroxyalkyl, C.sub.1 -C.sub.10 alkoxyalkyl, C.sub.1-C.sub.10 aryl, C.
    Type: Grant
    Filed: May 13, 1996
    Date of Patent: January 20, 1998
    Inventors: Raghavan Rajagopalan, Ella Y. Fung
  • Delta.sup.1,6 bicyclo ?4,4,0! functional dyes for contrast enhancement in optical imaging
    Patent number: 5672333
    Abstract: This invention provides functional dyes of the general formula: ##STR1## wherein R1, R2, and R.sup.5 may be the same or different and are selected from the group consisting of hydrogen, C.sub.1 -C.sub.10 alkyl, C.sub.1 -C.sub.10 alkoxyl, hydroxyl, C.sub.1 -C.sub.10 hydroxyalkyl, C.sub.1 -C.sub.10 alkoxyalkyl, C.sub.1 -C.sub.10 aryl, carboxyl, C.sub.1 -C.sub.10 carboxylalkyl, halogen, nitro, C.sub.1 -C.sub.10 alkoxycarbonyl, mercapto, C.sub.1 -C.sub.10 mercaptoalkyl, C.sub.1 -C.sub.10 alkylthio, sulfonate, and --(CH.sub.2).sub.m --N(R.sup.6)(R.sup.7) wherein R.sup.6 and R.sup.7 are independently hydrogen or C.sub.1 -C.sub.10 alkyl, C.sub.1 -C.sub.10 acyl, and R.sup.6 and R.sup.7 are capable of forming 5, 6, or 7 membered rings which may optionally be substituted with --O--, --NR.sup.8, or --S--; R.sup.3 and R.sup.4 may be the same or different and are selected from the group consisting of C.sub.1 -C.sub.10 alkyl, C.sub.1 -C.sub.10 hydroxyalkyl, C.sub.1 -C.sub.10 alkoxyalkyl, C.sub.1 -C.sub.10 aryl, C.sub.1 -C.
    Type: Grant
    Filed: May 13, 1996
    Date of Patent: September 30, 1997
    Assignee: Mallinckrodt Medical, Inc.
    Inventors: Raghavan Rajagopalan, Ella Y. Fung
  • Delta 1,2 bicyclo?4,4,0! functional dyes for contrast enhancement in optical imaging
    Patent number: 5672332
    Abstract: This invention provides functional dyes of the general formula: ##STR1## wherein R.sup.1, R.sup.2, and R.sup.5 may be the same or different and are selected from the group consisting of hydrogen, C.sub.1 -C.sub.10 allkyl, C.sub.1 -C.sub.10 alkoxyl, hydroxyl, C.sub.1 -C.sub.10 hydroxyalkyl, C.sub.1 -C.sub.10 alkoxyalkyl, C.sub.1 -C.sub.10 aryl, carboxyl, C.sub.1 -C.sub.10 carboxylalkyl, halogen, nitro, C.sub.1 -C.sub.10 alkoxycarbonyl, mercapto, C.sub.1 -C.sub.10 mercaptoalkyl, C.sub.1 -C.sub.10 alkylthio, sulfonate, and --(CH.sub.2).sub.m --N(R.sup.6)(R.sup.7) wherein R.sup.6 and R.sup.7 are independently hydrogen or C.sub.1 -C.sub.10 alkyl, C.sub.1 -C.sub.10 acyl, and R.sup.6 and R.sup.7 are capable of forming 5, 6, or 7 membered rings which may optionally be substituted with --O--, --NR.sup.8, or --S--; R.sup.3 and R.sup.4 may be the same or different and are selected from the group consisting of C.sub.1 -C.sub.10 alkyl, C.sub.1 -C.sub.10 hydroxyalkyl, C.sub.1 -C.sub.10 alkoxyalkyl, C.sub.1 -C.sub.
    Type: Grant
    Filed: May 13, 1996
    Date of Patent: September 30, 1997
    Assignee: Mallinckrodt Medical, Inc.
    Inventors: Ella Y. Fung, Raghavan Rajagopalan
  • Tungsten clusters
    Patent number: 5641472
    Abstract: The present invention provides new tri-tungsten compounds of the general structure: ##STR1## wherein R.sup.1 is --C.sub.k H.sub.1 Z.sub.m or --(C.sub.k H.sub.1 Z.sub.n) (C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; R.sup.2 is --C.sub.k H.sub.1 Z.sub.m or --(C.sub.k H.sub.1 Z.sub.n) (C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; R.sup.3 is --C.sub.k H.sub.1 Z.sub.m or --(C.sub.k H.sub.1 Z.sub.n) (C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; R.sup.4 is --(C.sub.k H.sub.1 Z.sub.m) or --(C.sub.k H.sub.1 Z.sub.n) (C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; R.sup.5 is --C.sub.k H.sub.1 Z.sub.m or --(C.sub.k H.sub.1 Z.sub.n) (C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; R.sup.6 is --C.sub.k H.sub.1 Z.sub.m or --(C.sub.k H.sub.1 Z.sub.n) (C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; Z is a functional group attachable on aliphatic chains or aromatic rings; R.sup.7 is an anionic molecule, neutral molecule, --C.sub.k H.sub.1 Z.sub.m or --(C.sub.k H.sub.1 Z.sub.n) (C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; R.sup.8 is an anionic molecule, neutral molecule, --C.sub.k H.sub.
    Type: Grant
    Filed: July 20, 1995
    Date of Patent: June 24, 1997
    Inventors: Ella Y. Fung, Stephen R. Cooper
  • Process for producing tungsten clusters
    Patent number: 5602268
    Abstract: The present invention provides a process for producing compounds of the general formula: ##STR1## wherein R.sup.1 is --C.sub.k H.sub.l Z.sub.m or --(C.sub.k H.sub.l Z.sub.n)(C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; R.sup.2 is --C.sub.k H.sub.l Z.sub.m or --(C.sub.k H.sub.l Z.sub.n)(C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; R.sup.3 is --C.sub.k H.sub.l Z.sub.m or --(C.sub.k H.sub.l Z.sub.n)(C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; R.sup.4 is --(C.sub.k H.sub.l Z.sub.m) or --(C.sub.k H.sub.l Z.sub.n)(C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; R.sup.5 is --C.sub.k H.sub.l Z.sub.m or --(C.sub.k H.sub.l Z.sub.n)(C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; R.sup.6 is --C.sub.k H.sub.l Z.sub.m or --(C.sub.k H.sub.l Z.sub.n)(C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; Z is a functional group attachable on aliphatic chains or aromatic rings; R.sup.7 is an anionic molecule, neutral molecule, --C.sub.k H.sub.l Z.sub.m or --(C.sub.k H.sub.l Z.sub.n)(C.sub.6 H.sub.(5-q) Z.sub.q).sub.p ; R.sup.8 is an anionic molecule, neutral molecule, --C.sub.k H.sub.
    Type: Grant
    Filed: July 20, 1995
    Date of Patent: February 11, 1997
    Assignee: Mallinckrodt Medical, Inc.
    Inventor: Ella Y. Fung