Patents by Inventor Ellen Baxter

Ellen Baxter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-amino-quinazoline derivatives useful as inhibitors of ?-secretase (BACE)
    Patent number: 8426429
    Abstract: The present invention is directed to novel 2-amino-3,4-dihydro-quinazoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of ?-secretase, also known as ?-site cleaving enzyme and BACE.
    Type: Grant
    Filed: August 4, 2005
    Date of Patent: April 23, 2013
    Assignee: Jansssen Pharmaceutica N.V.
    Inventors: Ellen Baxter, Robert Boyd, Steven J. Coats, Alfonzo D. Jordan, Allen B. Reitz, Charles H. Reynolds, Mark Schulz, Malcolm Scott
  • 2-amino-quinazoline derivatives useful as inhibitors of ?-secretase (BACE)
    Patent number: 8383637
    Abstract: The present invention is directed to novel 2-amino-3,4-dihydro-quinazoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of ?-secretase, also known as ?-site cleaving enzyme and BACE.
    Type: Grant
    Filed: August 4, 2005
    Date of Patent: February 26, 2013
    Assignee: Jansssen Pharmaceutica N.V.
    Inventors: Ellen Baxter, Francois Paul Bischoff, Robert E. Boyd, Mirielle Braeken, Steve Coats, Yifang Huang, Alfonzo D. Jordan, Chi Luo, Marc Hubert Mercken, Serge Maria Aloysius Pieters, Allen B. Reitz, Charles H. Reynolds, Tina Morgan Ross, Brett A. Tounge, Mark J. Schulz, Hans Louis Jos De Winter
  • 6-substituted-thio-2-amino-quinoline derivatives useful as inhibitors of ?-secretase (BACE)
    Patent number: 8076358
    Abstract: The present invention is directed to 6-substituted-thio-2-amino-quinoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD), mild cognitive impairment, senility and/or dementia. The compounds of the present invention are inhibitors of ?-secretase, also known as ?-site amyloid cleaving enzyme, BACE, BACE1, Asp2, or memapsin2.
    Type: Grant
    Filed: January 27, 2009
    Date of Patent: December 13, 2011
    Assignee: Janssen Pharmaceutica NV
    Inventors: Ellen Baxter, Christopher J. Creighton, Tianbao Lu, Allen B. Reitz, Charles H. Reynolds, Tina Morgan Ross, Ellen Sieber-McMaster
  • 2-amino-quinoline derivatives useful as inhibitors of ?-secretase (BACE)
    Patent number: 7868022
    Abstract: The present invention is directed to 2-amino-quinoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of ?-secretase, also known as ?-site cleaving enzyme and BACE, BACE1, Asp2 and memapsin2.
    Type: Grant
    Filed: February 6, 2007
    Date of Patent: January 11, 2011
    Assignee: Janssen Pharmaceutica NV
    Inventors: Ellen Baxter, Allen B. Reitz, Umar Saibu Mohomed Maharoof, Yifang Huang, Christopher John Creighton, Charles H. Reynolds, Chi Luo, Brett A. Tounge, Tina Morgan Ross, Tianbao Lu
  • 2-amino-quinoline derivatives useful as inhibitors of ?-secretase (BACE)
    Patent number: 7786116
    Abstract: The present invention is directed to novel 2-amino-quinoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD), mild cognitive impairment, senility and/or dementia. The compounds of the present invention are inhibitors of ?-secretase, also known as ?-site amyloid cleaving enzyme, BACE, BACE1, Asp2, or memapsin2.
    Type: Grant
    Filed: January 29, 2009
    Date of Patent: August 31, 2010
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Ellen Baxter, Christopher J. Creighton, Chih Yung Ho, Yifang Huang, Tianbao Lu, Chi Luo, Allen B. Reitz, Charles H. Reynolds, Tina Morgan Ross, Ellen Sieber-McMaster
  • 6-SUBSTITUTED-THIO-2-AMINO-QUINOLINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE)
    Publication number: 20090227627
    Abstract: The present invention is directed to 6-substituted-thio-2-amino-quinoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD), mild cognitive impairment, senility and/or dementia. The compounds of the present invention are inhibitors of ?-secretase, also known as ?-site amyloid cleaving enzyme, BACE, BACE1, Asp2, or memapsin2.
    Type: Application
    Filed: January 27, 2009
    Publication date: September 10, 2009
    Inventors: Ellen Baxter, Christopher J. Creighton, Tianbao Lu, Allen B. Reitz, Charles H. Reynolds, Tina Morgan Ross, Ellen Sieber-McMaster
  • 2-AMINO-QUINOLINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE)
    Publication number: 20090227581
    Abstract: The present invention is directed to novel 2-amino-quinoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD), mild cognitive impairment, senility and/or dementia. The compounds of the present invention are inhibitors of ?-secretase, also known as ?-site amyloid cleaving enzyme, BACE, BACE1, Asp2, or memapsin2.
    Type: Application
    Filed: January 29, 2009
    Publication date: September 10, 2009
    Inventors: Ellen Baxter, Christopher J. Creighton, Chih Yung Ho, Yifang Huang, Tianbao Lu, Chi Luo, Allen B. Reitz, Charles H. Reynolds, Tina Morgan Ross, Ellen Siber-McMaster
  • 2-AMINO-QUINOLINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE)
    Publication number: 20080194624
    Abstract: The present invention is directed to 2-amino-quinoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of ?-secretase, also known as ?-site cleaving enzyme and BACE, BACE1, Asp2 and memapsin2.
    Type: Application
    Filed: February 6, 2007
    Publication date: August 14, 2008
    Inventors: Ellen Baxter, Allen B. Reitz, Umar Saibu Mohomed Maharoof, Yifang Huang, Christopher John Creighton, Charles H. Reynolds, Chi Luo, Brett A. Tounge, Tina Morgan Ross, Tianbao Lu
  • NOVEL 2-AMINO-3,4-DIHYDRO-PYRIDO[3,4-D]PYRIMIDINE DERIVATIVES USEFUL AS INHIBITORS OF beta-SECRETASE (BACE)
    Publication number: 20070259898
    Abstract: The present invention is directed to novel 2-amino-3,4-dihydro-pyrido[3,4-d]pyrimidine derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of ?-secretase, also known as ?-site cleaving enzyme and BACE, BACE1, Asp2 and memapsin2.
    Type: Application
    Filed: October 25, 2006
    Publication date: November 8, 2007
    Inventors: Ellen Baxter, Christopher Creighton, Yifang Huang, Chi Luo, Michael Parker, Allen Reitz, Charles Reynolds, Tina Ross, Eric Strobel, Brett Tounge
  • 2-AMINO-3,4-DIHYDRO-QUINOLINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE)
    Publication number: 20070232642
    Abstract: The present invention is directed to 2-amino-3,4-dihydro-quinoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of ?-secretase, also known as ?-site cleaving enzyme and BACE, BACE1, Asp2 and memapsin2.
    Type: Application
    Filed: February 6, 2007
    Publication date: October 4, 2007
    Inventors: Ellen Baxter, Allen Reitz, Christopher Crieghton
  • MACROCYCLE DERIVATIVES USEFUL AS INHIBITORS OF beta-SECRETASE (BACE)
    Publication number: 20070232630
    Abstract: The present invention is directed to macrocycle derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of ?-secretase, also known as ?-site cleaving enzyme and BACE, BACE1, Asp2 and memapsin2.
    Type: Application
    Filed: February 6, 2007
    Publication date: October 4, 2007
    Inventors: Ellen Baxter, Allen Reitz, Michael Parker, Yifang Huang, Chih Ho, Eric Strobel, Charles Reynolds
  • Dihydroindolyl methanones as alpha 1a/1d adrenoreceptor modulators for the treatment of benign prostatic hypertrophy and lower urinary tract symptoms
    Publication number: 20060183902
    Abstract: The present invention relates to new compounds of Formula (I): and pharmaceutically acceptable forms thereof, use of the compounds as ?1a and/or ?1d adrenoreceptor modulators, including use of a pharmaceutical composition, medicine or medicament comprising said compounds, a process to prepare said compounds and a method for treating an ?1a and/or ?1d adrenoreceptor mediated disorder.
    Type: Application
    Filed: February 14, 2006
    Publication date: August 17, 2006
    Inventors: Ellen Baxter, Samuel Nortey, Allen Reitz, Virginia Pulito, Steven Middleton
  • Benzyl substituted (piperidin-4-yl)aminobenzamido derivatives
    Publication number: 20060106066
    Abstract: The present invention is directed to N-benzyl substituted (piperidin-4-yl)aminobenzamido derivatives which are delta-opioid receptor modulators.
    Type: Application
    Filed: December 21, 2005
    Publication date: May 18, 2006
    Inventors: Ellen Baxter, Allen Reitz
  • Novel 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE)
    Publication number: 20060079687
    Abstract: The present invention is directed to novel 2-amino-3,4-dihydro-quinazoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of ?-secretase, also known as ?-site cleaving enzyme and BACE.
    Type: Application
    Filed: August 4, 2005
    Publication date: April 13, 2006
    Inventors: Ellen Baxter, Francois Bischoff, Robert Boyd, Mirielle Braeken, Steve Coats, Yifang Huang, Alfonzo Jordan, Chi Luo, Marc Mercken, Serge Maria Pieters, Allen Reitz, Charles Reynolds, Tina Ross, Brett Tounge, Mark Schulz, Hans De Winter
  • Novel 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE)
    Publication number: 20060079686
    Abstract: The present invention is directed to novel 2-amino-3,4-dihydro-quinazoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of ?-secretase, also known as ?-site cleaving enzyme and BACE.
    Type: Application
    Filed: August 4, 2005
    Publication date: April 13, 2006
    Inventors: Ellen Baxter, Robert Boyd, Steven Coats, Alfonzo Jordan, Allen Reitz, Charles Reynolds, Malcolm Scott
  • Tub with lid
    Patent number: D459225
    Type: Grant
    Filed: November 5, 1999
    Date of Patent: June 25, 2002
    Assignee: Kraft Foods, Inc.
    Inventors: Marcia Ellen Baxter, Laurence Lhommel