Abstract: A method and system for managing and organizing objects in a virtual workspace is disclosed. The method and system display a plurality of objects and containers on the virtual workspace. The objects and containers are assigned to corresponding layers. The method and system receive user input for changing the corresponding layer of one or more of the objects and containers, recursively fit test each of the layers for an overlap between the one or more of the objects and containers and each container assigned to each layer based on the user input, incorporate the one or more objects and containers into a target container assigned to a target layer when the overlap exceeds a predetermined threshold, and assigns the one or more of the objects and containers to a background layer when the overlap fails to exceed the predetermined threshold in the fit testing.

Abstract: Described herein are methods for identifying and nominating on- and off-target CRISPR editing sites with improved accuracy and sensitivity.

Abstract: Method and system for managing and organizing objects in a virtual workspace including displaying a plurality of objects and containers on the virtual workspace, the objects and containers being assigned to corresponding layers; receiving user input for changing the corresponding layer of one or more of the objects and containers; recursively fit testing each of the layers for an overlap between the one or more of the objects and containers and each container assigned to each layer based on the user input; incorporating the one or more of the objects and containers into a target container assigned to a target layer when the overlap exceeds a predetermined threshold; and assigning the one or more of the objects and containers to a background layer when the overlap fails to exceed the predetermined threshold in the fit testing.

Abstract: The present invention is an article of manufacture comprising a dish and a marker moveably affixed upon or within the dish, wherein the marker can be moved with a utensil. In a preferred embodiment, a dish is constructed that has an inner section and an outer section, and a space between the two sections. The space is filled with a fluid in which markers that appeal to children, such as brightly colored fish. The markers contain a magnet which can be activated using flatware. The child uses his or her spoon to move the fish marker up the side of the dish. This teaches the child how to use a utensil and provides entertainment during mealtimes.