Abstract: The present invention relates to anti-IL-36R binding compounds, in particular new anti-IL-36R antibodies and therapeutic and diagnostic methods and compositions for using the same.

Abstract: This present invention relates to an illuminated source of light used for illuminating specific areas, such as door handles, door locks, door knobs and more. The source of light comprises an integrated light source, such as a plurality of LED lights, that can be turned ON manually or automatically based on motion detection of an approaching individual or object. Additionally, the source of light may be automatically turned OFF after a predetermined duration of time has elapsed in order to conserve battery life. The illuminated source of light offers a functional and decorative lighting solution for illuminating dark or dimly lit areas, such as dwelling entries.

Abstract: This present invention relates to an illuminated source of light used for illuminating specific areas, such as door handles, door locks, door knobs and more. The source of light comprises an integrated light source, such as a plurality of LED lights, that can be turned ON manually or automatically based on motion detection of an approaching individual or object. Additionally, the source of light may be automatically turned OFF after a predetermined duration of time has elapsed in order to conserve battery life. The illuminated source of light offers a functional and decorative lighting solution for illuminating dark or dimly lit areas, such as dwelling entries.

Abstract: The present invention relates to anti-IL-36R binding compounds, in particular new anti-IL-36R antibodies and therapeutic and diagnostic methods and compositions for using the same.

Abstract: The present invention relates to anti-interleukin-36R (anti-IL-36R) binding compounds, in particular new anti-IL-36R antibodies and therapeutic and diagnostic methods and compositions for using the same.

Abstract: An accessory device (20) for a stroller has a body (42) with a central portion (44) between opposed free ends (46) of the body and has an infant car seat mount (120) carried on the body (42) near at least one of the free ends of the body (42). The accessory device (20) is configured to at least partially widthwise traverse a frame assembly of a stroller (10) when installed on the frame assembly. The accessory device (20) is selectively removable from and attachable to the frame assembly, whereby the infant car seat mount (120) is also removable from and attachable relative to the frame assembly in concert with the accessory device.

Abstract: The present invention relates to anti-IL-36R binding compounds, in particular new anti-IL-36R antibodies and therapeutic and diagnostic methods and compositions for using the same.

Abstract: An accessory device (20) for a stroller has a body (42) with a central portion (44) between opposed free ends (46) of the body and has an infant car seat mount (120) carried on the body (42) near at least one of the free ends of the body (42). The accessory device (20) is configured to at least partially widthwise traverse a frame assembly of a stroller (10) when installed on the frame assembly. The accessory device (20) is selectively removable from and attachable to the frame assembly, whereby the infant car seat mount (120) is also removable from and attachable relative to the frame assembly in concert with the accessory device.

Abstract: The present invention relates to anti-IL-36R binding compounds, in particular new anti-IL-36R antibodies and therapeutic and diagnostic methods and compositions for using the same.

Abstract: The present invention relates to anti-interleukin-36R (anti-IL-36R) binding compounds, in particular new anti-IL-36R antibodies and therapeutic and diagnostic methods and compositions for using the same.

Abstract: A thermal measurement system that includes a light collection device and a detection system in communication with the device. The detection system includes two detection subsystems, wherein one subsystem is configured to detect light from a surface of an object, while the other subsystem is configured to detect light from the surface and a gas. The present invention has been described in terms of specific embodiment(s), and it is recognized that equivalents, alternatives, and modifications, aside from those expressly stated, are possible and within the scope of the appending claims.

Abstract: The present invention relates to anti-IL-36R binding compounds, in particular new anti-IL-36R antibodies and therapeutic and diagnostic methods and compositions for using the same.

Abstract: A thermal measurement system that includes a light collection device and a detection system in communication with the device. The detection system includes two detection subsystems, wherein one subsystem is configured to detect light from a surface of an object, while the other subsystem is configured to detect light from the surface and a gas. The present invention has been described in terms of specific embodiment(s), and it is recognized that equivalents, alternatives, and modifications, aside from those expressly stated, are possible and within the scope of the appending claims.

Abstract: This invention relates to a method for administering a pharmaceutically useful anticoagulant drug to certain suitable patients and a method for identifying those patients suitable for receiving the drug. In particular, the invention surrounds the identification of an association between certain SNPs in the apoB gene and susceptibility to increased levels of alanine aminotransferase (ALAT) following ximelagatran administration. Thus, this invention relates to methods for predicting susceptibility to elevated ALAT following ximelagatran administration and to methods for administering a pharmaceutically useful anticoagulant drug to certain suitable patients.

Abstract: This invention relates to a method for administering a pharmaceutically useful anticoagulant drug to certain suitable patients and a method for identifying those patients suitable for receiving the drug. In particular, the invention surrounds the identification of an association between certain SNPs in the MGST3 gene and susceptibility to increased levels of alanine aminotransferase (ALAT) following ximelagatran administration. Thus, this invention relates to methods for predicting susceptibility to elevated ALAT following ximelagatran administration and to methods for administering a pharmaceutically useful anticoagulant drug to certain suitable patients.

Abstract: This invention relates to a method for administering a pharmaceutically useful anticoagulant drug to certain suitable patients and a method for identifying those patients suitable for receiving the drug. In particular, the invention surrounds the identification of an association between HLA-DRB1*07 allele and susceptibility to increased levels of alanine aminotransferase (ALAT) following ximelagatran administration. Thus, this invention relates to methods for predicting susceptibility to elevated ALAT following ximelagatran administration and to methods for administering a pharmaceutically useful anticoagulant drug to certain suitable patients.

Abstract: This invention relates to a method for administering a pharmaceutically useful anticoagulant drug to certain suitable patients and a method for identifying those patients suitable for receiving the drug. In particular, the invention surrounds the identification of an association between certain SNPs in the PON1 gene and susceptibility to increased levels of alanine aminotransferase (ALAT) following ximelagatran or tacrine administration. Thus, this invention relates to methods for predicting susceptibility to elevated ALAT following ximelagatran or tacrine administration and to methods for administering a pharmaceutically useful anticoagulant drug to certain suitable patients.