Abstract: The present invention relates to a monoclonal antibody platform designed to be coupled to therapeutic peptides to increase the half-life of the therapeutic peptide in a subject. The invention also relates to pharmaceutical compositions and methods for use thereof.

Abstract: Provided herein are, inter alia, compositions (e.g., vaccine compositions (e.g., vaccine booster compositions)) comprising a hIL-10R binding agent (e.g., a hIL-10R binding protein (or a nucleic acid molecule comprising the same)) and optionally an immunogen (e.g., an immunogenic protein (or a nucleic acid molecule encoding the same)). Further provided herein are methods of utilizing hIL-10R binding agents (e.g., hIL-10R binding proteins (or nucleic acid molecules comprising the same)), including, e.g., in methods of vaccination, e.g., as vaccine boosters.

Abstract: The reclining child car seat with adjustable head support is a child safety seat. The reclining child car seat with adjustable head support comprises a seat structure, a harness, a locking hinge, and a rack and pinion structure. The seat structure further comprises a bench, a backrest, and a headrest. The reclining child car seat with adjustable head support is a reclining structure that is further defined with a cant. The reclining child car seat with adjustable head support is further configured such that the protective structure of the headrest automatically adjusts as a function of the cant of the reclining structure of the reclining child car seat with adjustable head support. The locking hinge attaches the backrest to the bench such that the backrest rotates relative to the bench. The rack and pinion structure forms a mechanical linkage that adjusts the headrest as a function of the cant. The harness secures the client in the seat structure.