Patents by Inventor Ellen Filvaroff

Ellen Filvaroff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20060073552
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: September 12, 2002
    Publication date: April 6, 2006
    Inventors: Kevin Baker, Dan Eaton, Ellen Filvaroff, Audrey Goddard, J. Grimaldi, Austin Gurney, Victoria Smith, Jean Stephan, Colin Watanabe, William Wood, Zemin Zhang, Sherman Fong
  • Methods and compositions for modulating and detecting wisp activity
    Publication number: 20060073135
    Abstract: Methods and compositions for use in modulating the activity(s) of WISP-1 polypeptide are pronided. WISP-1 antagonists inlcude anti-WISP-1 antiboties, WISP-1 immunoadhesins and WISP-1 variants (and fusion proteins thereof) which inhibit or neutralize induction or secretion of IIAS2, IIA, CD4 or RIIAMM by native human WISP-1 polypeptide in at least one type of cells or pathological conditions associated with native WISP-1 polypeptides.
    Type: Application
    Filed: June 28, 2003
    Publication date: April 6, 2006
    Applicant: Genentech, Inc.
    Inventors: Luc Desnoyers, Ellen Filvaroff
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20060073554
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: September 12, 2002
    Publication date: April 6, 2006
    Inventors: Kevin Baker, Dan Eaton, Ellen Filvaroff, Audrey Goddard, J. Grimaldi, Austin Gurney, Victoria Smith, Jean Stephan, Colin Watanabe, William Wood, Zemin Zhang, Sherman Fong
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20060073548
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: September 11, 2002
    Publication date: April 6, 2006
    Inventors: Kevin Baker, Dan Eaton, Ellen Filvaroff, Audrey Goddard, J. Grimaldi, Austin Gurney, Victoria Smith, Jean Stephan, Colin Watanabe, William Wood, Zemin Zhang, Sherman Fong
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20060073555
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: September 12, 2002
    Publication date: April 6, 2006
    Inventors: Kevin Baker, Dan Eaton, Ellen Filvaroff, Audrey Goddard, J. Grimaldi, Austin Gurney, Victoria Smith, Jean Stephan, Colin Watanabe, William Wood, Zemin Zhang, Sherman Fong
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20060074033
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: September 12, 2002
    Publication date: April 6, 2006
    Inventors: Kevin Baker, Dan Eaton, Ellen Filvaroff, Audrey Goddard, J. Grimaldi, Austin Gurney, Victoria Smith, Jean-Philippe Stephan, Colin Watanabe, William Wood, Zemin Zhang, Sherman Fong
  • Nucleic acids encoding secreted polypeptides that stimulate release of proteoglycans from cartilage
    Patent number: 7018837
    Abstract: The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: March 28, 2006
    Assignee: Genentech, Inc.
    Inventors: Kevin P. Baker, David Botstein, Dan L. Eaton, Napoleone Ferrara, Ellen Filvaroff, Mary E. Gerritsen, Audrey Goddard, Paul J. Godowski, J. Christopher Grimaldi, Austin L. Gurney, Kenneth J. Hillan, Ivar J. Kljavin, Mary A. Napier, Margaret Ann Roy, Daniel Tumas, William I. Wood
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20060051779
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: April 11, 2005
    Publication date: March 9, 2006
    Inventors: Dan Eaton, Ellen Filvaroff, Mary Gerritsen, Audrey Goddard, Paul Godowski, J. Grimaldi, Austin Gurney, Colin Watanabe, William Wood
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20060051792
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: July 15, 2005
    Publication date: March 9, 2006
    Inventors: Kevin Baker, Dan Eaton, Ellen Filvaroff, Audrey Goddard, J. Grimaldi, Austin Gurney, Victoria Smith, Jean Stephan, Colin Watanabe, William Wood, Zemin Zhang, Sherman Fong
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20060040351
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: October 22, 2004
    Publication date: February 23, 2006
    Inventors: Kevin Baker, Maureen Beresini, Laura DeForge, Luc Desnoyers, Ellen Filvaroff, Wei-Qiang Gao, Mary Gerritsen, Audrey Goddard, Paul Godowski, Austin Gurney, Steven Sherwood, Victoria Smith, Timothy Stewart, Daniel Tumas, Colin Watanabe, William Wood, Zemin Zhang
  • Screening assays and methods of tumor treatment
    Publication number: 20060015952
    Abstract: The invention relates generally to the screening of candidate molecules for the treatment of tumor metastasis, and treatment methods using such molecules. Thus, the invention includes a method of screening comprising the steps of: (1) administering a plurality of test substances to a non-human syngeneic immunocompetent animal model bearing at least one soft tissue or bone metastasis, in the presence or absence of a primary tumor; (2) determining the effects of the test substances on the soft tissue or bone metastasis and growth of the primary tumor, if present; and (3) identifying a test substance that inhibits the growth of a soft tissue or bone metastasis, without adverse effect on the status of the primary tumor, if present.
    Type: Application
    Filed: November 4, 2004
    Publication date: January 19, 2006
    Inventor: Ellen Filvaroff
  • SECRETED AND TRANSMEMBRANE POLYPEPTIDES AND NUCLEIC ACIDS ENCODING THE SAME
    Publication number: 20060008901
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: May 8, 2002
    Publication date: January 12, 2006
    Applicant: Genentech, Inc.
    Inventors: Dan Eaton, Ellen Filvaroff, Mary Gerritsen, Audrey Goddard, Paul Godowski, J. Grimaldi, Austin Gurney, Colin Watanabe, William Wood
  • Humanized anti-TGF-beta antibodies
    Publication number: 20050276802
    Abstract: Humanized anti-TGF-beta antibodies are provided, as well as methods for their preparation and use, including methods for treating TGF-beta disorders, for example, cancer. Also provided are articles of manufacture designed for various uses that contain the humanized antibodies.
    Type: Application
    Filed: March 31, 2005
    Publication date: December 15, 2005
    Applicant: Genentech, Inc.
    Inventors: Camellia Adams, Napoleone Ferrara, Ellen Filvaroff, Weiguang Mao, Leonard Presta, Max Tejada
  • Nucleic acid encoding PRO211 polypeptides
    Patent number: 6974689
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: December 13, 2005
    Assignee: Genentech, Inc.
    Inventors: Avi Ashkenazi, David Botstein, Luc Desnoyers, Dan L. Eaton, Napoleone Ferrara, Ellen Filvaroff, Sherman Fong, Wei-Qiang Gao, Hanspeter Gerber, Mary E. Gerritsen, Audrey Goddard, Paul J. Godowski, J. Christopher Grimaldi, Austin L. Gurney, Kenneth J. Hillan, Ivar J. Kljavin, Jennie P. Mather, James Pan, Nicholas F. Paoni, Margaret Ann Roy, Timothy A. Stewart, Daniel Tumas, P. Mickey Williams, William I. Wood
  • Antibodies to polypeptides encoded by a nucleic acid underexpressed in esophageal tumor
    Publication number: 20050260647
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: April 8, 2005
    Publication date: November 24, 2005
    Inventors: Dan Eaton, Ellen Filvaroff, Mary Gerritsen, Audrey Goddard, Paul Godowski, J. Grimaldi, Austin Gurney, Colin Watanabe, William Wood
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20050227328
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: May 13, 2005
    Publication date: October 13, 2005
    Applicant: Genentech, Inc.
    Inventors: Avi Ashkenazi, Kevin Baker, David Botstein, Luc Desnoyers, Dan Eaton, Napoleone Ferrara, Ellen Filvaroff, Sherman Fong, Wei-Qiang Gao, Hanspeter Gerber, Mary Gerritsen, Audrey Goddard, Paul Godowski, J. Grimaldi, Austin Gurney, Kenneth Hillan, Ivar Kljavin, Sophia Kuo, Mary Napier, James Pan, Nicholas Paoni, Margaret Roy, David Shelton, Timothy Stewart, Daniel Tumas, P. Williams, William Wood
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20050227342
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: October 19, 2001
    Publication date: October 13, 2005
    Inventors: Avi Ashkenazi, Kevin Baker, David Botstein, Luc Desnoyers, Dan Eaton, Napoleone Ferrara, Ellen Filvaroff, Sherman Fong, Wei-Qiang Gao, Hanspeter Gerber, Mary Gerritsen, Audrey Goddard, Paul Godowski, J. Grimaldi, Austin Gurney, Kenneth Hillan, Ivar Kljavin, Sophia Kuo, Mary Napier, James Pan, Nicholas Paoni, Margaret Roy, David Shelton, Timothy Stewart, Daniel Tumas, P. Williams, William Wood
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20050214904
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: October 20, 2004
    Publication date: September 29, 2005
    Applicant: GENENTECH, INC.
    Inventors: Avi Ashkenazi, David Botstein, Luc Desnoyers, Dan Eaton, Napoleone Ferrara, Ellen Filvaroff, Sherman Fong, Wei-Qiang Gao, Hanspeter Gerber, Mary Gerritsen, Audrey Goddard, Paul Godowski, Christopher Grimaldi, Austin Gurney, Kenneth Hillan, Ivar Kljavin, Jennie Mather, James Pan, Nicholas Paoni, Margaret Roy, Timothy Stewart, Daniel Tumas, P. Williams, William Wood
  • Method of inducing fetal hemoglobin synthesis
    Patent number: 6936254
    Abstract: The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: August 30, 2005
    Assignee: Genentech, Inc.
    Inventors: Kevin P. Baker, David Botstein, Dan L. Eaton, Napoleone Ferrara, Ellen Filvaroff, Mary E. Gerritsen, Audrey Goddard, Paul J. Godowski, J. Christopher Grimaldi, Austin L. Gurney, Kenneth J. Hillan, Ivar J. Kljavin, Mary A. Napier, Margaret Ann Roy, Daniel Tumas, William I. Wood
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20050153396
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention used to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: September 29, 2004
    Publication date: July 14, 2005
    Inventors: Kevin Baker, Maureen Beresini, Laura DeForge, Luc Desnoyers, Ellen Filvaroff, Wei-Qiang Gao, Mary Gerritsen, Audrey Goddard, Paul Godowski, Austin Gurney, Steven Sherwood, Victoria Smith, Timothy Stewart, Daniel Tumas, Colin Watanabe, William Wood, Zemin Zhang