Patents by Inventor Ellen J. Collarini

Ellen J. Collarini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-Kv1.3 antibodies, and methods of production and use thereof
    Patent number: 11597763
    Abstract: Anti-Kv1.3 antibodies (mAbs), particularly mAbs that specifically bind to Kv1.3 with high affinity and/or inhibit Kv1.3 function, are disclosed. The amino acid sequences of the CDRs of the light chains and the heavy chains, as well as consensus sequences for these CDRs, of these anti-Kv1.3 mAbs are provided. Additionally, canonical structures for CDRs in the VH and VL regions of anti-Kv1.3 antibodies are provided. The disclosure also provides nucleic acid molecules encoding the anti-Kv1.3 mAbs, expression vectors, host cells, methods for making the anti-Kv1.3 mAbs, and methods for expressing the anti-Kv1.3 mAbs. Finally, methods of using the anti-Kv1.3 mAbs as therapeutics, such as for preventing or treating an autoimmune disorder, are disclosed.
    Type: Grant
    Filed: May 2, 2017
    Date of Patent: March 7, 2023
    Assignee: Tetragenetics, Inc.
    Inventors: Paul A. Colussi, Janna Bednenko, Yelena Bisharyan, Ashot Papoyan, Joanna Cardarelli, Theodore G. Clark, Douglas Kahn, Lore Mariën, Bas Van Der Woning, Hans De Haard, William D. Harriman, Ellen J. Collarini, Alka Agrawal
  • ANTI-Kv1.3 ANTIBODIES, AND METHODS OF PRODUCTION AND USE THEREOF
    Publication number: 20190144538
    Abstract: Anti-Kv1.3 antibodies (mAbs), particularly mAbs that specifically bind to Kv1.3 with high affinity and/or inhibit Kv1.3 function, are disclosed. The amino acid sequences of the CDRs of the light chains and the heavy chains, as well as consensus sequences for these CDRs, of these anti-Kv1.3 mAbs are provided. Additionally, canonical structures for CDRs in the VH and VL regions of anti-Kv1.3 antibodies are provided. The disclosure also provides nucleic acid molecules encoding the anti-Kv1.3 mAbs, expression vectors, host cells, methods for making the anti-Kv1.3 mAbs, and methods for expressing the anti-Kv1.3 mAbs. Finally, methods of using the anti-Kv1.3 mAbs as therapeutics, such as for preventing or treating an autoimmune disorder, are disclosed.
    Type: Application
    Filed: May 2, 2017
    Publication date: May 16, 2019
    Applicant: Tetragenetics, Inc.
    Inventors: Paul A. Colussi, Janna Bednenko, Yelena Bisharyan, Ashot Papoyan, Joanna Cardarelli, Theodore G. Clark, Douglas Kahn, Lore Mariën, Bas Van Der Woning, Hans De Haard, William D. Harriman, Ellen J. Collarini
  • Anti-RSV G protein antibodies
    Patent number: 9321830
    Abstract: Individual monoclonal antibodies and fragments that bind a conserved epitope of the G protein of RSV and which are minimally immunogenic when administered to a human subject, are useful in treating RSV infections.
    Type: Grant
    Filed: September 25, 2012
    Date of Patent: April 26, 2016
    Assignee: Trellis RSV Holdings, Inc.
    Inventors: Lawrence M. Kauvar, Ellen J. Collarini, Bruce Keyt, Orit Foord
  • Antibodies immunoreactive with heregulin-coupled HER3
    Patent number: 9321839
    Abstract: Recombinant materials and methods for producing antibodies that specifically bind heregulin-coupled HER3, at a site distinct from the heregulin binding site, are described. These antibodies are particularly useful in treating cancer that expresses HER3.
    Type: Grant
    Filed: September 2, 2014
    Date of Patent: April 26, 2016
    Assignee: TRELLIS BIOSCIENCE, LLC
    Inventors: Bruce Keyt, Lawrence M. Kauvar, Ellen J. Collarini, Orit Foord, Gizette Sperinde, Marjan Fatholahi, Hung Nguyen
  • ANTIBODIES IMMUNOREACTIVE WITH HEREGULIN-COUPLED HER3
    Publication number: 20140370548
    Abstract: Recombinant materials and methods for producing antibodies that specifically bind heregulin-coupled HER3, at a site distinct from the heregulin binding site, are described. These antibodies are particularly useful in treating cancer that expresses HER3.
    Type: Application
    Filed: September 2, 2014
    Publication date: December 18, 2014
    Inventors: Bruce KEYT, Lawrence M. KAUVAR, Ellen J. COLLARINI, Orit FOORD, Gizette SPERINDE, Marjan FATHOLAHI, Hung NGUYEN
  • Antibodies immunoreactive with heregulin-coupled HER3
    Patent number: 8828388
    Abstract: Antibodies which specifically bind heregulin-coupled HER3, at a site distinct from the heregulin binding site, are described. These antibodies are particularly useful in treating cancer.
    Type: Grant
    Filed: January 17, 2013
    Date of Patent: September 9, 2014
    Assignee: Trellis Bioscience, LLC
    Inventors: Bruce Keyt, Lawrence M. Kauvar, Ellen J. Collarini, Orit Foord, Gizette Sperinde, Marjan Fatholahi, Hung Nguyen
  • ANTI-RSV G PROTEIN ANTIBODIES
    Publication number: 20130034564
    Abstract: Individual monoclonal antibodies and fragments that bind a conserved epitope of the G protein of RSV and which are minimally immunogenic when administered to a human subject, are useful in treating RSV infections.
    Type: Application
    Filed: September 25, 2012
    Publication date: February 7, 2013
    Inventors: Lawrence M. KAUVAR, Ellen J. Collarini, Bruce Keyt, Orit Foord
  • Antibodies immunoreactive with heregulin-coupled HER3
    Patent number: 8362215
    Abstract: Antibodies which specifically bind heregulin-coupled HER3, at a site distinct from the heregulin binding site, are described. These antibodies are particularly useful in treating cancer.
    Type: Grant
    Filed: April 29, 2010
    Date of Patent: January 29, 2013
    Assignee: Trellis Bioscience, LLC
    Inventors: Bruce Keyt, Lawrence M. Kauvar, Ellen J. Collarini, Orit Foord, Gizette Sperinde, Marjan Fatholahi, Hung Nguyen
  • Anti-RSV G protein antibodies
    Patent number: 8273354
    Abstract: Individual monoclonal antibodies and fragments that bind a conserved epitope of the G protein of RSV and which are minimally immunogenic when administered to a human subject, are useful in treating RSV infections.
    Type: Grant
    Filed: May 12, 2010
    Date of Patent: September 25, 2012
    Assignee: Trellis RSV Holdings, Inc.
    Inventors: Lawrence M. Kauvar, Ellen J. Collarini, Bruce Keyt, Orit Foord
  • Use of particulate labels in bioanalyte detection methods
    Patent number: 7939344
    Abstract: New applications for the use of distinguishable particulate labels available in a variety of hues and sized in the submicron range are described. These applications include profiling of cellular components, obtaining secretion patterns, identifying a multiplicity of components in chromatographic or electrophoretic techniques and identification of desired immunoglobulin secreting cells.
    Type: Grant
    Filed: August 8, 2008
    Date of Patent: May 10, 2011
    Assignee: Trellis Bioscience, Inc.
    Inventors: Lawrence M. Kauvar, Remy Cromer, William D. Harriman, Ellen J. Collarini
  • ANTIBODIES IMMUNOREACTIVE WITH HEREGULIN-COUPLED HER3
    Publication number: 20100310557
    Abstract: Antibodies which specifically bind heregulin-coupled HER3, at a site distinct from the heregulin binding site, are described. These antibodies are particularly useful in treating cancer.
    Type: Application
    Filed: April 29, 2010
    Publication date: December 9, 2010
    Inventors: Bruce KEYT, Lawrence M. KAUVAR, Ellen J. COLLARINI, Orit FOORD, Gizette SPERINDE, Marjan FATHOLAHI, Hung NGUYEN
  • ANTI-RSV G PROTEIN ANTIBODIES
    Publication number: 20100285022
    Abstract: Individual monoclonal antibodies and fragments that bind a conserved epitope of the G protein of RSV and which are minimally immunogenic when administered to a human subject, are useful in treating RSV infections.
    Type: Application
    Filed: May 12, 2010
    Publication date: November 11, 2010
    Inventors: Lawrence M. KAUVAR, Ellen J. Collarini, Bruce Keyt, Orit Foord
  • Anti-RSV G protein antibodies
    Patent number: 7736648
    Abstract: Individual monoclonal antibodies and fragments that bind a conserved epitope of the G protein of RSV and which are minimally immunogenic when administered to a human subject, are useful in treating RSV infections.
    Type: Grant
    Filed: October 24, 2008
    Date of Patent: June 15, 2010
    Assignee: Trellis Bioscience, Inc.
    Inventors: Lawrence M. Kauvar, Ellen J. Collarini, Bruce Keyt, Orit Foord
  • USE OF PARTICULATE LABELS IN BIOANALYTE DETECTION METHODS
    Publication number: 20090221434
    Abstract: New applications for the use of distinguishable particulate labels available in a variety of hues and sized in the submicron range are described. These applications include profiling of cellular components, obtaining secretion patterns, identifying a multiplicity of components in chromatographic or electrophoretic techniques and identification of desired immunoglobulin secreting cells.
    Type: Application
    Filed: August 8, 2008
    Publication date: September 3, 2009
    Inventors: Lawrence M. Kauvar, Remy Cromer, William D. Harriman, Ellen J. Collarini
  • ANTI-RSV G PROTEIN ANTIBODIES
    Publication number: 20090130120
    Abstract: Individual monoclonal antibodies and fragments that bind a conserved epitope of the G protein of RSV and which are minimally immunogenic when administered to a human subject, are useful in treating RSV infections.
    Type: Application
    Filed: October 24, 2008
    Publication date: May 21, 2009
    Inventors: Lawrence M. KAUVAR, Ellen J. Collarini, Bruce Keyt, Orit Foord
  • Use of particulate labels in bioanalyte detection methods
    Patent number: 7413868
    Abstract: New applications for the use of distinguishable particulate labels available in a variety of hues and sized in the submicron range are described. These applications include profiling of cellular components, obtaining secretion patterns, identifying a multiplicity of components in chromatographic or electrophoretic techniques and identification of desired immunoglobulin secreting cells.
    Type: Grant
    Filed: November 3, 2004
    Date of Patent: August 19, 2008
    Assignee: Trellis Bioscience, Inc.
    Inventors: Lawrence M. Kauvar, Remy Cromer, William D. Harriman, Ellen J. Collarini