Patents by Inventor Ellen Jessouroun

Ellen Jessouroun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing polysaccharide-protein conjugate vaccines
    Patent number: 9173931
    Abstract: Methods for the manufacture of polysaccharide-protein conjugate vaccines at high yield are provided. The methods involve reaction of a hydrazide group on one reactant with an aldehyde group on the other reactant. The reaction proceeds rapidly with a high conjugation efficiency. Simplified purification processes can be employed to separate the conjugate product from the unconjugated protein and polysaccharide and other small molecule by-products.
    Type: Grant
    Filed: August 6, 2004
    Date of Patent: November 3, 2015
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, Fiocruz
    Inventors: Ellen Jessouroun, Ivna Alana Freitas Brasileiro Da Silveira, Renata Chagas Bastos, Carl E. Frasch, Che-Hung Robert Lee
  • Process for preparing polysaccharide-protein conjugate vaccines
    Publication number: 20070110762
    Abstract: Methods for the manufacture of polysaccharide-protein conjugate vaccines at high yield are provided. The methods involve reaction of a hydrazide group on one reactant with an aldehyde group on the other reactant. The reaction proceeds rapidly with a high conjugation efficiency. Simplified purification processes can be employed to separate the conjugate product from the unconjugated protein and polysaccharide and other small molecule by-products.
    Type: Application
    Filed: August 6, 2004
    Publication date: May 17, 2007
    Applicant: Department Of Health And Human Services, Govt. of the United States of America
    Inventors: Ellen Jessouroun, Ivna Brasileiro Da Silveira, Renata Bastos, Carl Frasch, Che-Hung Lee