Patents by Inventor Ellen M. Leahy

Ellen M. Leahy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FACTOR VIIA INHIBITORS
    Publication number: 20020037912
    Abstract: The present invention provides novel compounds of Formula I: 1
    Type: Application
    Filed: August 10, 2001
    Publication date: March 28, 2002
    Inventor: Ellen M. Leahy
  • Peptides and compounds that bind to the IL-1 receptor
    Patent number: 5861476
    Abstract: Peptides that bind to the interleukin-1 type I receptor (IL-1RtI) can be used to assay the amount of IL-1R, or an IL-1R agonist or antagonist, in a sample and comprise a sequence of amino acids selected from the group consisting of (1) WXXXGZ.sub.1 W where Z.sub.1 is L, I, A, or Q; (2) XXQZ.sub.5 YZ.sub.6 XX where Z.sub.5 is P or Aze where Aze is azetidine; and Z.sub.6 is S, A, V, or L; and (3) Z.sub.23 NZ.sub.24 SZ.sub.25 Z.sub.26 Z.sub.27 Z.sub.28 Z.sub.29 Z.sub.30 L where Z.sub.23 is D or Y; Z.sub.24 is D or S; Z.sub.25 is S or W; Z.sub.26 is S or Y; Z.sub.27 is D or V; Z.sub.28 is S or W; Z.sub.29 is F or L; and Z.sub.30 is D or L; and where each amino acid is indicated by standard one letter abbreviation; and each X can be selected from any one of the 20 genetically coded L-amino acids or the stereoisomeric D-amino acids. Also provided are peptides which bind to the IL-1RtI, which are 11 to 40 amino acids in length, which comprise the core sequence of amino acids:Z.sub.31 XWZ.sub.32 Z.sub.33 Z.sub.34 Z.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: January 19, 1999
    Assignees: Affymax Technologies N.V., Hoechst Marion Roussel, Inc.
    Inventors: Ronald W. Barrett, Stephen D. Yanofsky, David Baldwin, Jeff W. Jacobs, Phillipe R. Bovy, Ellen M. Leahy, Richard S. Pottorf
  • Peptides and compounds that bind to the IL-1 receptor
    Patent number: 5786331
    Abstract: Peptides that bind to the interleukin-1 type I receptor (IL-1RtI) can be used to assay the amount of IL-1R, or an IL-1R agonist or antagonist, in a sample and comprise a sequence of amino acids selected from the group consisting of (1) WXXXGZ.sub.1 W where Z.sub.1 is L, I, A, or Q; (2) XXQZ.sub.5 YZ.sub.6 XX where Z.sub.5 is P or Aze where Aze is azetidine; and Z.sub.6 is S, A, V, or L; and (3) Z.sub.23 NZ.sub.24 SZ.sub.25 Z.sub.26 Z.sub.27 Z.sub.28 Z.sub.29 Z.sub.30 L where Z.sub.23 is D or Y; Z.sub.24 is D or S; Z.sub.25 is S or W; Z.sub.26 is S or Y; Z.sub.27 is D or V; Z.sub.28 is S or W; Z.sub.29 is F or L; and Z.sub.30 is D or L; and where each amino acid is indicated by standard one letter abbreviation; and each X can be selected from any one of the 20 genetically coded L-amino acids or the stereoisomeric D-amino acids. Also provided are peptides which bind to the IL-1RtI, which are 11 to 40 amino acids in length, which comprise the core sequence of amino acids:Z.sub.31 XWZ.sub.32 Z.sub.33 Z.sub.34 Z.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: July 28, 1998
    Assignees: Affymax Technologies N.V., Hoechst Marion Roussel, Inc.
    Inventors: Ronald W. Barrett, Stephen D. Yanofsky, David Baldwin, Jeff W. Jacobs, Phillipe R. Bovy, Ellen M. Leahy, Richard S. Pottorf