Patents by Inventor Ellen Strängberg

Ellen Strängberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ASBT INHIBITORS IN THE TREATMENT OF RENAL DISEASES
    Publication number: 20240207286
    Abstract: The invention relates to an apical sodium-dependent bile acid transport (ASBT) inhibitor for use in the treatment of renal diseases and disorders, such as cholemic nephropathy. Such treatment can include reducing serum bile acid concentrations, increasing urinary bile acids and improving liver as well as renal parameters.
    Type: Application
    Filed: December 11, 2023
    Publication date: June 27, 2024
    Inventors: Erik LINDSTRÖM, Ellen STRÄNGBERG, Jan HENGSTLER, Ahmed GHALLAB
  • BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS
    Publication number: 20240067617
    Abstract: The invention relates to 1,5-benzothiazepine and 1,2,5-benzothiadiazepine derivatives of formula (I). These compounds are bile acid modulators having apical sodium-dependent bile acid transporter (ASBT) and/or liver bile acid transport (LBAT) inhibitory activity. The invention also relates to pharmaceutical compositions comprising these compounds and to the use of these compounds in the treatment of cardiovascular diseases, fatty acid metabolism and glucose utilization disorders, gastrointestinal diseases and liver diseases.
    Type: Application
    Filed: July 5, 2023
    Publication date: February 29, 2024
    Inventors: Ingemar Starke, Per-Göran Gillberg, Santosh S. Kulkarni, Ellen Strängberg