Patents by Inventor Ellen T. O'Connor

Ellen T. O'Connor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODY PURIFICATION
    Publication number: 20160251441
    Abstract: Described herein is a method for separating antibody fragment impurities from target antibodies or desired fragments thereof.
    Type: Application
    Filed: October 23, 2014
    Publication date: September 1, 2016
    Applicant: MedImmune, LLC
    Inventors: Ellen T. O'CONNOR, Mutsa Y. KAMBARAMI, Matthew T. ASPELUND, Frank L. BARTNIK, Mark BERGE, Thoa BUI, Methal ALBARGHOUTHI, Jihong WANG, Jun KIM
  • METHODS FOR PROCESSING INCLUSION BODIES
    Publication number: 20130273607
    Abstract: The present application relates to methods for purifying recombinant proteins, including antibodies and antibody fragments. Suitably, the methods utilize depth filtration to clarify the desired proteins from a solubilized mixture, and provide refolding methods and refolding buffers to allow for refolding of the recombinant proteins into functional and active proteins. Exemplary antibody fragments include anti-CD22 antibody fragments that comprise VH and VL chains refolded into a functional and active fragment.
    Type: Application
    Filed: October 20, 2011
    Publication date: October 17, 2013
    Applicant: MEDIMMUNE, LLC
    Inventor: Ellen T. O'Connor