Patents by Inventor Ellen YOUNG

Ellen YOUNG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for recombinant dengue viruses or vaccine and diagnostic development
    Patent number: 12600752
    Abstract: The present invention provides compositions and methods of use comprising a chimeric dengue virus E glycoprotein comprising a dengue virus E glycoprotein backbone, which comprises amino acid substitutions that may introduce an epitope that is recognized by an antibody from a dengue virus serotype that is different from the dengue virus serotype of the dengue virus E glycoprotein backbone.
    Type: Grant
    Filed: November 20, 2020
    Date of Patent: April 14, 2026
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Ralph Baric, Ellen Young, Jennifer Munt
  • METHODS AND COMPOSITIONS FOR RECOMBINANT DENGUE VIRUSES FOR VACCINE AND DIAGNOSTIC DEVELOPMENT
    Publication number: 20250127871
    Abstract: The present invention provides compositions and methods of use comprising a chimeric dengue virus E glycoprotein comprising a dengue virus E glycoprotein backbone, which comprises amino acid substitutions that may introduce a domain and/or an epitope that is recognized by an antibody from a dengue virus serotype that is different from the dengue virus serotype of the dengue virus E glycoprotein backbone.
    Type: Application
    Filed: September 29, 2022
    Publication date: April 24, 2025
    Inventors: Ralph Baric, Aravinda de Silva, Ellen Young, Jennifer Munt, Deanna Zhu
  • METHODS AND COMPOSITIONS FOR RECOMBINANT DENGUE VIRUSES OR VACCINE AND DIAGNOSTIC DEVELOPMENT
    Publication number: 20230018080
    Abstract: The present invention provides compositions and methods of use comprising a chimeric dengue virus E glycoprotein comprising a dengue virus E glycoprotein backbone, which comprises amino acid substitutions that may introduce an epitope that is recognized by an antibody from a dengue virus serotype that is different from the dengue virus serotype of the dengue virus E glycoprotein backbone.
    Type: Application
    Filed: November 20, 2020
    Publication date: January 19, 2023
    Inventors: Ralph Baric, Ellen Young, Jennifer Munt
  • Methods and compositions for dengue virus serotype 4 epitopes
    Patent number: 11241491
    Abstract: The present invention provides compositions and methods of use comprising a chimeric dengue virus E glycoprotein comprising a dengue virus E glycoprotein backbone, which comprises amino acid substitutions that introduce a dengue virus E glycoprotein epitope from a dengue virus serotype that is different from the dengue virus serotype of the dengue virus E glycoprotein backbone.
    Type: Grant
    Filed: May 23, 2018
    Date of Patent: February 8, 2022
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Ralph Baric, Matthew Begley, Douglas Widman, Aravinda Desilva, Usha Nivarthi, Boyd Yount, Ellen Young
  • METHODS AND COMPOSITIONS FOR DENGUE VIRUS SEROTYPE 4 EPITOPES
    Publication number: 20200155663
    Abstract: The present invention provides compositions and methods of use comprising a chimeric dengue virus E glycoprotein comprising a dengue virus E glycoprotein backbone, which comprises amino acid substitutions that introduce a dengue virus E glycoprotein epitope from a dengue virus serotype that is different from the dengue virus serotype of the dengue virus E glycoprotein backbone.
    Type: Application
    Filed: May 23, 2018
    Publication date: May 21, 2020
    Inventors: Ralph BARIC, Matthew BEGLEY, Douglas WIDMAN, Aravinda DESILVA, Usha NIVARTHI, Boyd YOUNT, Ellen YOUNG