Patents by Inventor Ellie CARRELL

Ellie CARRELL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINED TRANSGENE AND INTRON-DERIVED MIRNA THERAPY FOR TREATMENT OF SCA1
    Publication number: 20220288101
    Abstract: Provided herein are nucleic acids that comprise both an expression cassette for a therapeutic protein (e.g., Ataxin-1-like) and an expression cassette for a therapeutic inhibitory RNA (e.g., a miRNA that targets ataxin-1 mRNA). In some instances, the expression cassette for the therapeutic inhibitor RNA lies within an intron of the expression cassette for the therapeutic protein. Also provided are methods of using the nucleic acids to treat spinocerebellar.
    Type: Application
    Filed: August 14, 2020
    Publication date: September 15, 2022
    Applicant: THE CHILDREN'S HOSPITAL OF PHILADELPHIA
    Inventors: Beverly L. DAVIDSON, Ellie CARRELL, Alejandro Mas MONTEYS, Megan S. KEISER