Patents by Inventor Elliot Botvinick

Elliot Botvinick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220079474
    Abstract: Provided herein is a stabilized oxygen transport matrix that includes a reversible oxygen binding protein, such as hemoglobin, immobilized throughout the stabilized oxygen transport matrix. The stabilized oxygen transport matrix is used to transport oxygen and can be used as an oxygen transport region and a reaction region of an analyte sensor, such as an implantable glucose sensor. The reversible binding protein can also function as an oxygen probe within the analyte sensor.
    Type: Application
    Filed: September 28, 2021
    Publication date: March 17, 2022
    Inventors: Elliot Botvinick, Troy M. Bremer
  • Patent number: 11160474
    Abstract: Provided herein is a stabilized oxygen transport matrix that includes a reversible oxygen binding protein, such as hemoglobin, immobilized throughout the stabilized oxygen transport matrix. The stabilized oxygen transport matrix is used to transport oxygen and can be used as an oxygen transport region and a reaction region of an analyte sensor, such as an implantable glucose sensor. The reversible binding protein can also function as an oxygen probe within the analyte sensor.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: November 2, 2021
    Assignee: Metronom Health, Inc.
    Inventors: Elliot Botvinick, Troy M. Bremer
  • Patent number: 10149640
    Abstract: Disclosed herein are embodiments of methods and techniques for measuring oxygen levels of an implant. The implant can have a plurality of oxygen-sensitive microparticles incorporated throughout. The oxygen-sensitive microparticles can receive light and emit excitation light in response. The levels of excitation light emitted can be directly related to oxygen concentration in the implant.
    Type: Grant
    Filed: June 15, 2015
    Date of Patent: December 11, 2018
    Assignee: The Regents of the University of California
    Inventors: Elliot Botvinick, John Weidling
  • Publication number: 20160270703
    Abstract: Provided herein is a stabilized oxygen transport matrix that includes a reversible oxygen binding protein, such as hemoglobin, immobilized throughout the stabilized oxygen transport matrix. The stabilized oxygen transport matrix is used to transport oxygen and can be used as an oxygen transport region and a reaction region of an analyte sensor, such as an implantable glucose sensor. The reversible binding protein can also function as an oxygen probe within the analyte sensor.
    Type: Application
    Filed: May 27, 2016
    Publication date: September 22, 2016
    Inventors: Elliot Botvinick, Troy M. Bremer
  • Patent number: 9357952
    Abstract: Provided herein is a stabilized oxygen transport matrix that includes a reversible oxygen binding protein, such as hemoglobin, immobilized throughout the stabilized oxygen transport matrix. The stabilized oxygen transport matrix is used to transport oxygen and can be used as an oxygen transport region and a reaction region of an analyte sensor, such as an implantable glucose sensor. The reversible binding protein can also function as an oxygen probe within the analyte sensor.
    Type: Grant
    Filed: September 23, 2013
    Date of Patent: June 7, 2016
    Assignee: Metronom Health, Inc.
    Inventors: Elliot Botvinick, Troy M. Bremer
  • Patent number: 9321990
    Abstract: This invention relates to optomechanical systems and methods for altering, modifying or disrupting a target object. Such systems and methods are used for, for example, ablating the endogenous nucleus in a cell.
    Type: Grant
    Filed: September 16, 2011
    Date of Patent: April 26, 2016
    Assignees: The Regents of the University of California, University of Massachusetts
    Inventors: Michael W. Berns, Thoru Pederson, Elliot Botvinick, Linda Zhixia Shi
  • Publication number: 20150359472
    Abstract: Disclosed herein are embodiments of methods and techniques for measuring oxygen levels of an implant. The implant can have a plurality of oxygen-sensitive microparticles incorporated throughout. The oxygen-sensitive microparticles can receive light and emit excitation light in response. The levels of excitation light emitted can be directly related to oxygen concentration in the implant.
    Type: Application
    Filed: June 15, 2015
    Publication date: December 17, 2015
    Inventors: Elliot Botvinick, John Weidling
  • Patent number: 8844369
    Abstract: An apparatus and method for providing a gradient strain to an extracellular matrix to induce mechanotransduction. The gradient strain can be produced by adhering the extracellular matrix to a post and the walls of a sample holder, and then rotating the post and the sample holder. This strain can result in increased stiffness of the extracellular matrix with very little loss of pore size.
    Type: Grant
    Filed: April 26, 2012
    Date of Patent: September 30, 2014
    Assignee: The Regents of The University of California
    Inventors: Elliot Botvinick, Samir Shreim, Maxwell Kotlarchyk
  • Publication number: 20140163345
    Abstract: Provided herein is a stabilized oxygen transport matrix that includes a reversible oxygen binding protein, such as hemoglobin, immobilized throughout the stabilized oxygen transport matrix. The stabilized oxygen transport matrix is used to transport oxygen and can be used as an oxygen transport region and a reaction region of an analyte sensor, such as an implantable glucose sensor. The reversible binding protein can also function as an oxygen probe within the analyte sensor.
    Type: Application
    Filed: September 23, 2013
    Publication date: June 12, 2014
    Applicant: Metronom Health, Inc.
    Inventors: Elliot Botvinick, Troy M. Bremer
  • Patent number: 8543182
    Abstract: Provided herein is a stabilized oxygen transport matrix that includes a reversible oxygen binding protein, such as hemoglobin, immobilized throughout the stabilized oxygen transport matrix. The stabilized oxygen transport matrix is used to transport oxygen and can be used as an oxygen transport region and a reaction region of an analyte sensor, such as an implantable glucose sensor. The reversible binding protein can also function as an oxygen probe within the analyte sensor.
    Type: Grant
    Filed: June 29, 2006
    Date of Patent: September 24, 2013
    Assignee: Metronom Health, Inc.
    Inventors: Elliot Botvinick, Troy M. Bremer
  • Publication number: 20120272745
    Abstract: An apparatus and method for providing a gradient strain to an extracellular matrix to induce mechanotransduction. The gradient strain can be produced by adhering the extracellular matrix to a post and the walls of a sample holder, and then rotating the post and the sample holder. This strain can result in increased stiffness of the extracellular matrix with very little loss of pore size.
    Type: Application
    Filed: April 26, 2012
    Publication date: November 1, 2012
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Elliot Botvinick, Samir Shreim, Maxwell Kotlarchyk
  • Publication number: 20120129158
    Abstract: This invention relates to optomechanical systems and methods for altering, modifying or disrupting a target object. Such systems and methods are used for, for example, ablating the endogenous nucleus in a cell.
    Type: Application
    Filed: September 16, 2011
    Publication date: May 24, 2012
    Applicant: The Regents of the University of California
    Inventors: Michael W. Berns, Thoru Pederson, Elliot Botvinick, Linda Zhixia Shi
  • Publication number: 20060291041
    Abstract: A microscope fluid applicator includes an immersion fluid reservoir for storing immersion fluid and an applicator tip coupled to the immersion fluid reservoir. The microscope fluid applicator is releasably engaged to a moveable turret on a microscope. The microscope fluid applicator may be secured to an objective lens port on a turret of a microscope via threads. Immersion fluid is ejected from the applicator tip onto a sample holder. The turret may be rotated to place an immersion fluid objective into the immersion fluid. The sample may then be viewed through the immersion fluid. Any excess immersion fluid that is dispensed from the applicator tip may be collected in a fluid collector to prevent contamination of the microscope optics and other components.
    Type: Application
    Filed: June 20, 2006
    Publication date: December 28, 2006
    Applicant: The Regents of the University of California
    Inventors: Michael Berns, Elliot Botvinick, Craig Rappaport
  • Patent number: 7146203
    Abstract: Provided herein is a stabilized oxygen transport matrix that includes a reversible oxygen binding protein, such as hemoglobin, immobilized throughout the stabilized oxygen transport matrix. The stabilized oxygen transport matrix is used to transport oxygen and can be used as an oxygen transport region and a reaction region of an analyte sensor, such as an implantable glucose sensor. The reversible binding protein can also function as an oxygen probe within the analyte sensor.
    Type: Grant
    Filed: December 16, 2004
    Date of Patent: December 5, 2006
    Inventors: Elliot Botvinick, Troy M Bremer
  • Publication number: 20060241365
    Abstract: Provided herein is a stabilized oxygen transport matrix that includes a reversible oxygen binding protein, such as hemoglobin, immobilized throughout the stabilized oxygen transport matrix. The stabilized oxygen transport matrix is used to transport oxygen and can be used as an oxygen transport region and a reaction region of an analyte sensor, such as an implantable glucose sensor. The reversible binding protein can also function as an oxygen probe within the analyte sensor.
    Type: Application
    Filed: June 29, 2006
    Publication date: October 26, 2006
    Inventors: Elliot Botvinick, Troy Bremer
  • Publication number: 20050177035
    Abstract: Provided herein is a stabilized oxygen transport matrix that includes a reversible oxygen binding protein, such as hemoglobin, immobilized throughout the stabilized oxygen transport matrix. The stabilized oxygen transport matrix is used to transport oxygen and can be used as an oxygen transport region and a reaction region of an analyte sensor, such as an implantable glucose sensor. The reversible binding protein can also function as an oxygen probe within the analyte sensor.
    Type: Application
    Filed: December 16, 2004
    Publication date: August 11, 2005
    Inventors: Elliot Botvinick, Troy Bremer