Abstract: The presently disclosed subject matter relates to a method for finding and identifying sites or regions on cancer cells that are not possessed by normal cells (neoantigens). The method comprises creation of xenoantibodies which are able to specifically bind to cancer cell specific sites, and do not bind to, or cross react with normal cells. These neoantigens are used to plan and create cancer treatments.

Abstract: A method for performing enamel replacement on a tooth in the mouth of a person, the method including: beginning an arch reformulation therapy (ART) process, selecting a tooth for an enamel replacement process to be performed on, identifying a surface of the tooth to have a dental composite material adhered to as part of the enamel replacement process, discluding multiple teeth during the ART process including the selected tooth, preparing the identified surface of the selected tooth for adherence of a dental composite material, the preparation including application of a preparation material to the surface of the tooth, and applying the dental composite material to the prepared surface.

Abstract: A method for moving an existing implant along a jaw bone of a person, the method including positioning an abrasive bur between adjacent roots of the at least one tooth and existing implant in the jaw bone, rotating the abrasive bur, applying the rotating bur to penetrate the gingiva tissue covering the space between the adjacent roots of the at least one tooth and implant to remove a desired amount of gingival tissue and expose the underlying jaw bone, and contacting the bone with the rotating bur to abrasively vibrate the jaw bone adjacent to at least one tooth without drilling through the cortical bone.

Abstract: A method for performing enamel replacement on a tooth in the mouth of a person, the method including: beginning an arch reformulation therapy (ART) process, selecting a tooth for an enamel replacement process to be performed on, identifying a surface of the tooth to have a dental composite material adhered to as part of the enamel replacement process, discluding multiple teeth during the ART process including the selected tooth, preparing the identified surface of the selected tooth for adherence of a dental composite material, the preparation including application of a preparation material to the surface of the tooth, and applying the dental composite material to the prepared surface.

Abstract: A method for moving an existing implant along a jaw bone of a person, the method including positioning an abrasive bur between adjacent roots of the at least one tooth and existing implant in the jaw bone, rotating the abrasive bur, applying the rotating bur to penetrate the gingiva tissue covering the space between the adjacent roots of the at least one tooth and implant to remove a desired amount of gingival tissue and expose the underlying jaw bone, and contacting the bone with the rotating bur to abrasively vibrate the jaw bone adjacent to at least one tooth without drilling through the cortical bone.

Abstract: A method for increasing the velocity of at least one moving tooth along a jaw bone, the method including positioning an abrasive bur with a desired diameter between adjacent roots of the at least one tooth in the jaw bone, the abrasive bur being rotatable by a handheld device, rotating the abrasive bur with the handheld device, applying the rotating bur to penetrate the gingiva tissue covering the space between the adjacent roots of the at least one tooth in the jaw to remove a desired amount of gingival tissue and expose the underlying jaw bone, and contacting the bone with the rotating bur to abrasively vibrate the jaw bone adjacent to at least one tooth without drilling through the cortical bone.

Abstract: Inhibition of immune checkpoints in cancer patients may induce the patients B cells to generate antibodies against their cancer cells. The present disclosure provides methods for isolating, identifying, and characterizing these cancer-specific antibodies, and/or their antibodies/antigen binding sites. In particular, the presently disclosed methods relate to isolating, identifying, and characterizing cancer-specific antibodies from cancer patients in conjunction with an acute treatment of checkpoint inhibitor/s, and methods of generating cancer-specific medications thereof.

Abstract: A method for increasing the velocity of at least one moving tooth along a jaw bone, the method including positioning an abrasive bur with a desired diameter between adjacent roots of the at least one tooth in the jaw bone, the abrasive bur being rotatable by a handheld device, rotating the abrasive bur with the handheld device, applying the rotating bur to penetrate the gingiva tissue covering the space between the adjacent roots of the at least one tooth in the jaw to remove a desired amount of gingival tissue and expose the underlying jaw bone, and contacting the bone with the rotating bur to abrasively vibrate the jaw bone adjacent to at least one tooth without drilling through the cortical bone.

Abstract: The presently disclosed subject matter relates to a method for finding and identifying sites or regions on cancer cells that are not possessed by normal cells (neoantigens). The method comprises creation of xenoantibodies which are able to specifically bind to cancer cell specific sites, and do not bind to, or cross react with normal cells. These neoantigens are used to plan and create cancer treatments.

Abstract: The presently disclosed subject matter relates to a method for finding and identifying sites or regions on cancer cells that are not possessed by normal cells (neoantigens). The method comprises creation of xenoantibodies which are able to specifically bind to cancer cell specific sites, and do not bind to, or cross react with normal cells. These neoantigens are used to plan and create cancer treatments.

Abstract: Disclosed is a non-invasive method of realignment of maloccluded teeth of a patient suffering from a periodontal and/or an orthognathic condition that includes application of flexible aligners to induce the movement of the maloccluded teeth toward a realigned position along an ideal arch.

Abstract: A pattern recognition system and method wherein errors are reduced by creating independent error templates which correspond to patterns which tend to be erroneously matched and linked error templates which are linked to specified reference templates which are stored for comparison. Upon comparison with reference templates, independent error templates and linked error templates, the unknown pattern is identified as a match wherever its test template is most closely matched to a reference template, is identified as a non-match when its test template is most closely matched with an independent error template, and when most closely matched to a linked error template, the comparison criteria are revised and further comparison(s) are made.