Patents by Inventor Elliot S. Barnathan

Elliot S. Barnathan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunotargeting of plasminogen activators to the pulmonary endothelium
    Patent number: 5653979
    Abstract: A multimolecular complex made up of a plasminogen activator conjugated to anti-ACE Mab 9B9 capable of delivering the plasminogen activator to the pulmonary endothelium is provided. Methods of using this complex to selectively deliver the plasminogen activator to the pulmonary endothelium to enhance fibrinolysis in the lungs of an animal are also provided. In addition, a method of prolonging the time a plasminogen activator is present in the circulation of an animal by conjugating the plasminogen activator to anti-ACE Mab 9B9 is also provided.
    Type: Grant
    Filed: March 30, 1995
    Date of Patent: August 5, 1997
    Assignee: Trustees of the University of Pennsylvania
    Inventors: Vladimir R. Muzykantov, Elliot S. Barnathan