Patents by Inventor Elma Fernandes
Elma Fernandes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20100158918Abstract: The invention provides polypeptides, designated herein as SECP polypeptides, as well as polynucleotides encoding SECP polypeptides, and antibodies that immunospecifically-bind to SECP polypeptide or polynucleotide, or derivatives, variants, mutants, or fragments thereof. The invention additionally provides methods in which the SECP polypeptide, polynucleotide, and antibody are used in the detection, prevention, and treatment of a broad range of pathological states.Type: ApplicationFiled: March 1, 2010Publication date: June 24, 2010Inventors: Richard A. Shimkets, Elma Fernandes
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Publication number: 20080171046Abstract: Disclosed herein are novel human nucleic acid sequences which encode polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: May 12, 2004Publication date: July 17, 2008Inventors: Corine Vermet, Elma Fernandes, Richard Shimkets, John Herrmann, Kumud Majumder, John MacDougall, Vishnu Mishra, Peter S. Mezes, Luca Rastelli
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Patent number: 7253266Abstract: The present invention provides FGF-CX, a novel isolated polypeptide, as well as a polynucleotide encoding FGF-CX and antibodies that immunospecifically bind to FGF-CX or any derivative, variant, mutant, or fragment of the FGF-CX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the FGF-CX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as other uses.Type: GrantFiled: June 17, 2002Date of Patent: August 7, 2007Assignee: CuraGen CorporationInventors: Richard A. Shimkets, Michael Jeffers, Sudhirdas K. Prayaga, Ferenc L. Boldog, Meijia Yang, Catherine Burgess, Elma Fernandes, John L. Herrmann, William J. LaRochelle, Henri Lichenstein, Linda Gorman, Mei Zhong, Muralidhara Padigaru, Carol E. A. Pena, John P. Alsobrook, II, Denise M. Lepley, Daniel K. Rieger, William Grosse
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Publication number: 20070166756Abstract: The invention provides polypeptides, designated herein as SECP polypeptides, as well as polynucleotides encoding SECP polypeptides, and antibodies that immunospecifically-bind to SECP polypeptide or polynucleotide, or derivatives, variants, mutants, or fragments thereof. The invention additionally provides methods in which the SECP polypeptide, polynucleotide, and antibody are used in the detection, prevention, and treatment of a broad range of pathological states.Type: ApplicationFiled: March 15, 2007Publication date: July 19, 2007Inventors: Richard Shimkets, Elma Fernandes
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Publication number: 20060257882Abstract: This application is drawn to novel nucleic acid sequences encoding mammalian polypeptides that have sequence similarity to human breast tumor-associated protein 47. The nucleic acid sequence is 1987 nucleotides long and contains an open reading frame from nucleotides 991 to 1447. The novel, encoded polypeptides comprise 152 amino acid residues.Type: ApplicationFiled: April 21, 2005Publication date: November 16, 2006Inventors: Richard Shimkets, Elma Fernandes, John Herrman, Corine Vernet
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Patent number: 7056885Abstract: The present invention provides FGF-CX polypeptides and polynucleotides, and antibodies that immunospecifically bind to FGF-CX or any derivative, variant, mutant, or fragment of the FGF-CX polypeptide, polynucleotide or antibody. The invention additionally provides methods of use for the FGF-CX polypeptide, polynucleotide and antibody.Type: GrantFiled: July 3, 2000Date of Patent: June 6, 2006Assignee: CuraGen CorporationInventors: Michael Jeffers, Richard A. Shimkets, Sudhirdas K. Prayaga, Ferenc L. Boldog, Meijia Yang, Catherine Burgess, Elma Fernandes, John L. Herrmann, William J. LaRochelle, Henri Lichenstein
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Publication number: 20060111561Abstract: Disclosed are novel proteins and nucleic acids encoding same. Also disclosed are vectors, host cells, antibodies and recombinant methods for producing the proteins and polynucleotides, as well as methods for using same.Type: ApplicationFiled: August 31, 2005Publication date: May 25, 2006Inventors: Valerie Gerlach, Elma Fernandes, Richard Shimkets, Meera Patturajan, Vladimir Gusev, Stacie Navara, Velizar Tchernev, David Anderson, Xiaojia Guo, Luca Rastelli, Mei Zhong, Muralidhara Padigaru
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Publication number: 20060094647Abstract: The present invention is based upon methods of treating inflammatory conditions in the intestinal tract of mammals using growth factor related polypeptides. Methods of using fibroblast growth factor-CX (FGF-CX) polynucleotide sequences and the FGF-CX polypeptides encoded by such nucleic acid sequences, or variants, fragments and homologs thereof, are claimed in the invention. Similarly, methods of using FCTRX polynucleotide sequences and the FCTRX polypeptides encoded by such nucleic acid sequences, or variants, fragments and homologs thereof, alone or in combination, are also claimed in the invention. FCTRX collectively refers to any of six variant FCTRX sequences, variously designated FCTR1, FCTR2, FCTR3, FCTR4, FCTR5 and FCTR6.Type: ApplicationFiled: November 6, 2001Publication date: May 4, 2006Inventors: Michael Jeffers, Richard Shimkets, Sudhirdas Prayaga, Ferenc Boldog, Meijia Yang, Catherine Burgess, Elma Fernandes, Beth Rittman, Juliette Shimkets, William LaRochelle, Henri Lichenstein
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Publication number: 20060057664Abstract: The invention provides polypeptides, designated herein as SECP polypeptides, as well as polynucleotides encoding SECP polypeptides, and antibodies that immunospecifically-bind to SECP polypeptide or polynucleotide, or derivatives, variants, mutants, or fragments thereof. The invention additionally provides methods in which the SECP polypeptide, polynucleotide, and antibody are used in the detection, prevention, and treatment of a broad range of pathological states.Type: ApplicationFiled: June 2, 2003Publication date: March 16, 2006Applicant: CuraGen CorporationInventors: Richard Shimkets, Elma Fernandes
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Patent number: 7001766Abstract: This application is drawn to novel nucleic acid sequences encoding mammalian polypeptides that have sequence similarity to human angiopoietin-related proteins. The nucleic acid sequence is 1855 nucleotides long and contains an open reading frame from nucleotides 154-6 to 1369-71. The encoded polypeptides are about 405 amino acid residues in length.Type: GrantFiled: October 23, 2001Date of Patent: February 21, 2006Assignee: CuraGen CorporationInventors: Richard A. Shimkets, Elma Fernandes
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Publication number: 20050208040Abstract: The invention provides polypeptides, designated herein as PROX polypeptides, as well as polynucleotides encoding PROX polypeptides, and antibodies that immunospecifically-bind to PROX polypeptide or polynucleotide, or derivatives, variants, mutants, or fragments thereof. The invention additionally provides methods in which the PROX polypeptide, polynucleotide, and antibody are used in the detection, prevention, and treatment of a broad range of pathological states.Type: ApplicationFiled: January 28, 2005Publication date: September 22, 2005Applicant: CuraGen CorporationInventors: Richard Shimkets, Elma Fernandes
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Publication number: 20050170380Abstract: The present invention provides novel isolated SECX polynucleotides and the membrane-associated or secreted polypeptides encoded by the SECX polynucleotides. Also provided are the antibodies that immunospecifically bind to a SECX polypeptide or any derivative, variant, mutant or fragment of the SECX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the SECX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.Type: ApplicationFiled: October 21, 2004Publication date: August 4, 2005Applicant: CuraGen CorporationInventors: Elma Fernandes, Corine Vernet, Richard Shimkets, David Anderson, Muralidhara Padigaru, Ferenc Boldog, Li Li, Suresh Shenoy, Stacie Casman, Luca Rastelli
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Publication number: 20050153305Abstract: Disclosed herein are novel human nucleic acid sequences which encode polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: May 21, 2004Publication date: July 14, 2005Inventors: Corine Vernet, Catherine Burgess, Elma Fernandes, Raymond Taupier, Kerry Quinn, Kimberly Spytek, Luca Rastelli, John Herrmann
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Publication number: 20050063971Abstract: The present invention provides FGF-CX, a novel isolated polypeptide, as well as a polynucleotide encoding FGF-CX and antibodies that immunospecifically bind to FGF-CX or any derivative, variant, mutant, or fragment of the FGF-CX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the FGF-CX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as other uses.Type: ApplicationFiled: September 23, 2004Publication date: March 24, 2005Inventors: Michael Jeffers, Richard Shimkets, Sudhirdas Prayaga, Ferenc Boldog, Meijia Yang, Catherine Burgess, Elma Fernandes, John Herrmann, William LaRochelle, Henri Lichenstein
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Publication number: 20040162236Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: March 31, 2003Publication date: August 19, 2004Inventors: John Alsobrook, Patricia Bento, Ferenc Boldog, Catherine Burgess, Stacie Casman, Julie Crabtree Bokor, Shlomit R. Edinger, Karen Ellerman, Elma Fernandes, Valerie Gerlach, William Grosse, Erik Gunther, Vladimir Gusev, Melvyn Heyes, Denise Lepley, Li Li, John R. MacDougall, Uriel M. Malyankar, Isabelle Millet, Meera Patturajan, John A. Peyman, Luca Rastelli, Daniel Rieger, Suresh Shenoy, Richard Shimkets, Glennda Smithson, David Stone, Corine Vernet, Edward Voss
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Publication number: 20040147003Abstract: The present invention provides novel isolated NOVX polynucleotides and polypeptides encoded by the NOVX polynucleotides. Also provided are the antibodies that immunospecifically bind to a NOVX polypeptide or any derivative, variant, mutant or fragment of the NOVX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the NOVX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.Type: ApplicationFiled: September 22, 2003Publication date: July 29, 2004Inventors: Richard Shimkets, Henri Lichenstein, Corine Vernet, Elma Fernandes
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Publication number: 20040067505Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: May 1, 2003Publication date: April 8, 2004Inventors: Enrique Alvarez, David Anderson, Ferenc Boldog, Elina Catterton, Shlomit R. Edinger, Elma Fernandes, Valerie Gerlach, Linda Gorman, William Grosse, Xiaojia (Sasha) Guo, Weizhen Ji, Ramesh Kekuda, Li Li, John R. MacDougall, Muralidhara Padigaru, Meera Patturajan, Jeffery D. Peterson, Luca Rastelli, Richard Shimkets, Kimberly Spytek, David J. Stone, Corine A.M. Vernet, Edward Voss, Mei Zhong
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Publication number: 20040010119Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: February 12, 2002Publication date: January 15, 2004Inventors: Xiaojia Guo, Elma Fernandes, Li Li, Ramesh Kekuda, Yi Liu, Mario Leite, Kimberly A. Spytek, Weizhen Ji, Stacie J. Casman, Ference L. Boldog, Meera Patturajan, Corine A. M. Vernet, Robert A. Ballinger, Uriel M. Malyankar, Velizar T. Tchernev, Angela D. Blalock, Vladimir Y. Gusev, Luca Rastelli, Peter D. Mezes, Karen Ellerman, Melvyn Heyes, John L. Herrmann, Richard A. Shimkets, Noelle Ioime, Carol E. A. Pena, Suresh G. Shenoy, Raymond J. Taupier, Valerie Gerlach, Linda Gorman
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Publication number: 20030211485Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: May 29, 2002Publication date: November 13, 2003Inventors: Valerie L. Gerlach, John R. MacDougall, David J. Stone, Glennda Smithson, Muralidhara Padigaru, Catherine Burgess, Corine Vernet, Elma Fernandes, Richard A. Shimkets, Velizar T. Tchernev, Vishnu Mishra, Stacie Casman, Kimberly A. Spytek, Bryan Zerhusen
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Publication number: 20030199103Abstract: This application is drawn to novel amino acid sequences for mammalian polypeptides that have sequence similarity to a protein fragment of human epidermal growth factor. The polypeptides are novel secreted proteins of approximately 708 amino acids.Type: ApplicationFiled: October 15, 2001Publication date: October 23, 2003Applicant: CuraGen CorporationInventors: Richard A. Shimkets, Elma Fernandes, John Herrman, Corine Vernet